Search Results - "Hopmans, Sarah"
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Functional connectivity and quality of life in young adults with cerebral palsy: a feasibility study
Published in BMC neurology (23-10-2020)“…Abstract Background Cerebral Palsy (CP) is a group of disorders that affect the development of movement and posture. CP results from injuries to the immature…”
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GnRH antagonist associates with less adiposity and reduced characteristics of metabolic syndrome and atherosclerosis compared with orchiectomy and GnRH agonist in a preclinical mouse model
Published in Urologic oncology (01-11-2014)“…Abstract Objectives Observational studies relate androgen deprivation therapy (ADT) to metabolic syndrome (MS) and cardiovascular disease, an association…”
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Lovastatin sensitizes lung cancer cells to ionizing radiation: modulation of molecular pathways of radioresistance and tumor suppression
Published in Journal of thoracic oncology (01-03-2011)“…In this study, we investigated the effect of the 3-hydroxy-3-methylgutaryl-CoA reductase inhibitor lovastatin, as a sensitizer of lung cancer cells to ionizing…”
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Endoplasmic reticulum protein ERp46 in renal cell carcinoma
Published in PloS one (03-03-2014)“…An established inverse clinical correlation between serum adiponectin levels and renal cell carcinoma (RCC) aggressiveness exists. We have recently…”
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Inhibition of carbonic anhydrase IX (CA9) sensitizes renal cell carcinoma to ionizing radiation
Published in Oncology reports (01-10-2015)“…While normal kidneys are relatively sensitive to ionizing radiation (IR), renal cell carcinoma (RCC) is considered radioresistant. Carbonic anhydrase IX (CA9),…”
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Protective effect of pharmacological castration on metabolic perturbations and cardiovascular disease in the hyperglycemic male ApoE−/−:Ins2+/Akita mouse model
Published in Prostate cancer and prostatic diseases (01-06-2021)“…Background Unlike in other mouse models of atherogenesis, it has recently been suggested that orchiectomy plays a role in attenuating atherosclerosis and…”
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Correlates of Mental Health in Adolescents and Young Adults with Cerebral Palsy: A Cross-Sectional Analysis of the MyStory Project
Published in Journal of clinical medicine (29-05-2022)“…It is important to gain a better understanding of mental health issues in adolescents and young adults (AYA) with cerebral palsy (CP). In this cross-sectional…”
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Chronic modulation of AMP-Kinase, Akt and mTOR pathways by ionizing radiation in human lung cancer xenografts
Published in Radiation oncology (London, England) (18-05-2012)“…Earlier, we showed that in cancer cells, AMP-activated kinase (AMPK) participates in a signal transduction pathway involving ATM-AMPK-p53/p21cip1 which is…”
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Endoplasmic reticulum protein ERp46 in prostate adenocarcinoma
Published in Oncology letters (01-05-2017)“…Endoplasmic reticulum (ER) protein ERp46 is a member of the protein disulfide isomerase family of oxidoreductases, which facilitates the reduction of…”
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Underactivation of the adiponectin–adiponectin receptor 1 axis in clear cell renal cell carcinoma: implications for progression
Published in Clinical & experimental metastasis (01-02-2014)“…Energy-sensing pathways, normally coordinated by 5′ AMP-activated protein kinase (AMPK), are dysregulated in renal cell carcinoma (RCC). Obesity can accentuate…”
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Protective effect of pharmacological castration on metabolic perturbations and cardiovascular disease in the hyperglycemic male ApoE.sup.-/-:Ins2.sup.+/Akita mouse model
Published in Prostate cancer and prostatic diseases (01-06-2021)“…Background Unlike in other mouse models of atherogenesis, it has recently been suggested that orchiectomy plays a role in accelerating atherosclerosis and…”
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MP37-05 ERP46 MEDIATES PROSTATE CANCER TUMORIGENESIS
Published in The Journal of urology (01-04-2015)Get full text
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Abstract 596: Androgen Deprivation Therapy--Induced Weight Gain and Atherosclerosis in Prostate Cancer: Differences Between Orchiectomy, GnRH Agonist and Antagonist
Published in Arteriosclerosis, thrombosis, and vascular biology (01-05-2014)“…Abstract only Cardiovascular disease (CVD) is one of the most common causes of mortality in prostate cancer patients. In prostate cancer treatment androgen…”
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Abstract 4960: ERp46 (thioredoxin domain-containing protein 5, TXND5) promotes prostate cancer growth in vitro and in vivo
Published in Cancer research (Chicago, Ill.) (01-08-2015)“…Abstract We have recently demonstrated that endoplasmic reticulum protein ERp46, a member of the protein disulfide isomerase family of oxidoreductases, TXND5,…”
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The role of FSH in castration-induced adipogenesis: Highlighting differences between orchiectomy, GNRH agonists, and antagonists
Published in Journal of clinical oncology (20-05-2013)“…Abstract only e16011 Background: Androgen deprivation therapy (ADT) results in weight gain and development of the metabolic syndrome. Inspired by the…”
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MP39-05 INHIBITION OF CARBONIC ANHYDRASE IX CONFERS RADIATION SENSITIVITY TO RENAL CELL CARCINOMA
Published in The Journal of urology (01-04-2015)Get full text
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Psychometric properties of the English language version of the C-BiLLT evaluated in typically developing Canadian children
Published in Journal of pediatric rehabilitation medicine (01-01-2023)“…This study aimed to 1) investigate the convergent and discriminant validity, internal consistency, and test-retest reliability of the Canadian English version…”
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The role of FSH in castration-induced adipogenesis and cardiovascular diseases: Highlighting differences between orchiectomy, GNRH agonists, and antagonists
Published in Journal of clinical oncology (01-02-2014)“…Abstract only 191 Background: Androgen deprivation therapy (ADT) is associated with weight gain and development of the metabolic syndrome (MS). Different modes…”
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Follicle-Stimulating Hormone Exacerbates Cardiovascular Disease in the Presence of Low or Castrate Testosterone Levels
Published in JACC. Basic to translational science (01-03-2024)“…[Display omitted] •Hypogonadism and PC are common in aging men and associate with cardiovascular disease. ADT to suppress T in PC patients also affects FSH.•We…”
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