Search Results - "Hopkins, Thomas G."
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The RNA-binding protein LARP1 is a post-transcriptional regulator of survival and tumorigenesis in ovarian cancer
Published in Nucleic acids research (18-02-2016)“…RNA-binding proteins (RBPs) are increasingly identified as post-transcriptional drivers of cancer progression. The RBP LARP1 is an mRNA stability regulator,…”
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Depletion of LAG‐3+ T Cells Translated to Pharmacology and Improvement in Psoriasis Disease Activity: A Phase I Randomized Study of mAb GSK2831781
Published in Clinical pharmacology and therapeutics (01-05-2021)“…Activated T cells drive a range of immune‐mediated inflammatory diseases. LAG‐3 is transiently expressed on recently activated CD4+ and CD8+ T cells. We…”
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Noninterventional statistical comparison of BTS and CHEST guidelines for size and severity in primary pneumothorax
Published in The European respiratory journal (01-06-2015)“…Primary spontaneous pneumothorax (PSP) occurs in apparently healthy young people with an incidence of 12.5 cases per 100000 per year [1]. Attempts to develop…”
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Adrenal venous sampling as a diagnostic procedure for primary hyperaldosteronism: Experience from a tertiary referral centre
Published in Hormones (Athens, Greece) (01-04-2012)“…CONTEXT Adrenal vein sampling (AVS) is recommended in all patients with hyperaldos-teronism to whom surgery would be offered if the results indicated…”
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Dreamm-3: A Phase 3, Open-Label, Randomized Study to Evaluate the Efficacy and Safety of Belantamab Mafodotin (GSK2857916) Monotherapy Compared with Pomalidomide Plus Low-Dose Dexamethasone (Pom/Dex) in Participants with Relapsed/Refractory Multiple Myeloma (RRMM)
Published in Blood (13-11-2019)“…▪ Background: Belantamab mafodotin is a humanized, afucosylated, anti-B-cell maturation antigen (BCMA) monoclonal antibody conjugated to monomethyl auristatin…”
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