Search Results - "Hopkins, Diane"
-
1
Ovarian recurrence risk assessment using machine learning, clinical information, and serum protein levels to predict survival in high grade ovarian cancer
Published in Scientific reports (27-11-2023)“…In ovarian cancer, there is no current method to accurately predict recurrence after a complete response to chemotherapy. Here, we develop a machine learning…”
Get full text
Journal Article -
2
Use of a glycomics array to establish the anti-carbohydrate antibody repertoire in type 1 diabetes
Published in Nature communications (01-11-2022)“…Type 1 diabetes (T1D) is an autoimmune disease, characterized by the presence of autoantibodies to protein and non-protein antigens. Here we report the…”
Get full text
Journal Article -
3
Planning a City through 'Dialogue': Deliberative Policy-making in Action in Western Australia
Published in Urban policy and research (01-09-2010)“…Deliberative policy-making is an alternative method of generating new planning strategies based on the public deliberation of citizens and stakeholders. Four…”
Get full text
Journal Article -
4
Retrospective Validation of a 168-Gene Expression Signature for Glioma Classification on a Single Molecule Counting Platform
Published in Cancers (25-01-2021)“…Gene expression profiling has been shown to be comparable to other molecular methods for glioma classification. We sought to validate a gene-expression based…”
Get full text
Journal Article -
5
Discovery and Validation of Serum Protein Changes in Type 1 Diabetes Patients Using High Throughput Two Dimensional Liquid Chromatography-Mass Spectrometry and Immunoassays
Published in Molecular & cellular proteomics (01-11-2011)“…Type 1 diabetes (T1D) is expected to cause significant changes in the serum proteome; however, few studies have systematically assessed the proteomic profile…”
Get full text
Journal Article -
6
Proteins of TNF-α and IL6 Pathways Are Elevated in Serum of Type-1 Diabetes Patients with Microalbuminuria
Published in Frontiers in immunology (31-01-2018)“…Soluble cytokine receptors may play an important role in development of microalbuminuria (MA) in type-1 diabetes (T1D). In this study, we measured 12 soluble…”
Get full text
Journal Article -
7
Serum Levels of Inflammatory Proteins Are Associated With Peripheral Neuropathy in a Cross-Sectional Type-1 Diabetes Cohort
Published in Frontiers in immunology (31-03-2021)“…Chronic low-grade inflammation is involved in the pathogenesis of type-1 diabetes (T1D) and its complications. In this cross-section study design, we…”
Get full text
Journal Article -
8
Elevated Serum Levels of Soluble TNF Receptors and Adhesion Molecules Are Associated with Diabetic Retinopathy in Patients with Type-1 Diabetes
Published in Mediators of Inflammation (01-01-2015)“…Aims. To examine the association of the serum levels of TNF receptors, adhesion molecules, and inflammatory mediators with diabetic retinopathy (DR) in T1D…”
Get full text
Journal Article -
9
Serum IL-1ra Is Associated with but Has No Genetic Link to Type 1 Diabetes
Published in Endocrines (13-09-2022)“…Interleukin-1 antagonism is a proposed biomarker and potential therapy for the delay and/or treatment of type 1 diabetes (T1D). We evaluated the role of…”
Get full text
Journal Article -
10
Serum protein profile at remission can accurately assess therapeutic outcomes and survival for serous ovarian cancer
Published in PloS one (11-11-2013)“…Biomarkers play critical roles in early detection, diagnosis and monitoring of therapeutic outcome and recurrence of cancer. Previous biomarker research on…”
Get full text
Journal Article -
11
The 3p21.31 genetic locus promotes progression to type 1 diabetes through the CCR2/CCL2 pathway
Published in Journal of translational autoimmunity (Online) (01-01-2021)“…Multiple cross-sectional and longitudinal studies have shown that serum levels of the chemokine ligand 2 (CCL-2) are associated with type 1 diabetes (T1D),…”
Get full text
Journal Article -
12
Chemokine (C-C motif) ligand 2 (CCL2) in sera of patients with type 1 diabetes and diabetic complications
Published in PloS one (12-04-2011)“…Chemokine (C-C motif) ligand 2 (CCL2), commonly known as monocyte chemoattractant protein-1 (MCP-1), has been implicated in the pathogenesis of many diseases…”
Get full text
Journal Article -
13
The risk factors for deep and superficial chest surgical-site infections after coronary artery bypass graft surgery are different
Published in The Journal of thoracic and cardiovascular surgery (01-07-2002)“…Objective: We sought to determine risk factors for deep and superficial chest wound infections after coronary artery bypass graft surgery to develop predictive…”
Get full text
Journal Article -
14
Genetically dependent ERBB3 expression modulates antigen presenting cell function and type 1 diabetes risk
Published in PloS one (26-07-2010)“…Type 1 diabetes (T1D) is an autoimmune disease resulting from the complex interaction between multiple susceptibility genes, environmental factors and the…”
Get full text
Journal Article -
15
Case‐Control Study of Pediatric Cardiothoracic Surgical Site Infections
Published in Infection control and hospital epidemiology (01-01-2008)“…A retrospective case‐control study was performed to determine the risks and outcomes associated with pediatric cardiothoracic surgical site infection…”
Get full text
Journal Article -
16
The High Osmolarity Glycerol Response (HOG) MAP Kinase Pathway Controls Localization of a Yeast Golgi Glycosyltransferase
Published in The Journal of cell biology (16-11-1998)“…The yeast α-1,3-mannosyltransferase (Mnn1p) is localized to the Golgi by independent transmembrane and lumenal domain signals. The lumenal domain is localized…”
Get full text
Journal Article -
17
Association of Early Exposure of Probiotics and Islet Autoimmunity in the TEDDY Study
Published in JAMA pediatrics (01-01-2016)“…Probiotics have been hypothesized to affect immunologic responses to environmental exposures by supporting healthy gut microbiota and could therefore…”
Get more information
Journal Article -
18
A candidate panel of eight urinary proteins shows potential of early diagnosis and risk assessment for diabetic kidney disease in type 1 diabetes
Published in Journal of proteomics (30-05-2024)“…Diabetic kidney disease (DKD) poses a significant health challenge for individuals with diabetes. At its initial stages, DKD often presents asymptomatically,…”
Get full text
Journal Article -
19
The Changing Discourse of City Plans: Rationalities of Planning in Perth, 1955-2010
Published in Planning theory & practice (01-12-2011)“…1 Plans are among the most durable products of planning, and as such offer a revealing window into the worlds of the planners of their time. In this paper we…”
Get full text
Journal Article -
20
Predicting Islet Cell Autoimmunity and Type 1 Diabetes: An 8-Year TEDDY Study Progress Report
Published in Diabetes care (01-06-2019)“…Assessment of the predictive power of The Environmental Determinants of Diabetes in the Young (TEDDY)-identified risk factors for islet autoimmunity (IA), the…”
Get full text
Journal Article