Search Results - "Hopfner, P."

Structural Biochemistry and Interaction Architecture of the DNA Double-Strand Break Repair Mre11 Nuclease and Rad50-ATPase by Hopfner, Karl-Peter, Karcher, Annette, Craig, Lisa, Woo, Tammy T., Carney, James P., Tainer, John A.

“…To clarify functions of the Mre11/Rad50 (MR) complex in DNA double-strand break repair, we report Pyrococcus furiosus Mre11 crystal structures, revealing a…”
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Monolithically Integrated Logic nor Gate Based on GaAs/AlGaAs Three-Terminal Junctions by Muller, C.R., Worschech, L., Hopfner, P., Hofling, S., Forchel, A.

“…Room-temperature operation of a logic NOR gate is demonstrated. The NOR gate is based on three three-terminal junctions (TTJs) monolithically integrated in a…”
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Structural Biology of Rad50 ATPase: ATP-Driven Conformational Control in DNA Double-Strand Break Repair and the ABC-ATPase Superfamily by Hopfner, Karl-Peter, Karcher, Annette, Shin, David S., Craig, Lisa, Arthur, L.Matthew, Carney, James P., Tainer, John A.

“…To clarify the key role of Rad50 in DNA double-strand break repair (DSBR), we biochemically and structurally characterized ATP-bound and ATP-free Rad50…”
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Molecular basis of human ATM kinase inhibition by Stakyte, K., Rotheneder, M., Lammens, K., Bartho, J. D., Grädler, U., Fuchß, T., Pehl, U., Alt, A., van de Logt, E., Hopfner, K. P.

“…Human checkpoint kinase ataxia telangiectasia-mutated (ATM) plays a key role in initiation of the DNA damage response following DNA double-strand breaks. ATM…”
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Elemental topological insulator with tunable Fermi level: strained α-Sn on InSb(001) by Barfuss, A, Dudy, L, Scholz, M R, Roth, H, Höpfner, P, Blumenstein, C, Landolt, G, Dil, J H, Plumb, N C, Radovic, M, Bostwick, A, Rotenberg, E, Fleszar, A, Bihlmayer, G, Wortmann, D, Li, G, Hanke, W, Claessen, R, Schäfer, J

“…We report on the epitaxial fabrication and electronic properties of a topological phase in strained α-Sn on InSb. The topological surface state forms in the…”
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Three-dimensional spin rotations at the Fermi surface of a strongly spin-orbit coupled surface system by Höpfner, P, Schäfer, J, Fleszar, A, Dil, J H, Slomski, B, Meier, F, Loho, C, Blumenstein, C, Patthey, L, Hanke, W, Claessen, R

“…The spin texture of the metallic two-dimensional electron system (sqrt[3]×sqrt[3])-Au/Ge(111) is revealed by fully three-dimensional spin-resolved…”
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Mre11 and Rad50 from Pyrococcus furiosus: Cloning and Biochemical Characterization Reveal an Evolutionarily Conserved Multiprotein Machine by Hopfner, K P, Karcher, A, Shin, D, Fairley, C, Tainer, J A, Carney, J P

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Converting blood coagulation factor IXa into factor Xa: dramatic increase in amidolytic activity identifies important active site determinants by Hopfner, Karl-Peter, Brandstetter, Hans, Karcher, Annette, Kopetzki, Erhard, Huber, Robert, Engh, Richard A., Bode, Wolfram

“…The coagulation factors IXa (fIXa) and Xa (fXa) share extensive structural and functional homology; both cleave natural substrates effectively only with a…”
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Renormalization of bulk magnetic electron states at high binding energies by Hofmann, A, Cui, X Y, Schäfer, J, Meyer, S, Höpfner, P, Blumenstein, C, Paul, M, Patthey, L, Rotenberg, E, Bünemann, J, Gebhard, F, Ohm, T, Weber, W, Claessen, R

“…The quasiparticle dynamics of electrons in a magnetically ordered state is investigated by high-resolution angle-resolved photoemission of Ni(110) at 10 K. The…”
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Valence band and core-level photoemission of Au/Ge(001): Band mapping and bonding sites by Meyer, S., Dudy, L., Schäfer, J., Blumenstein, C., Höpfner, P., Umbach, T. E., Dollinger, A., Cui, X. Y., Patthey, L., Claessen, R.

“…We have used photoemission spectroscopy in order to investigate the electronic states and chemical bonding related to Au induced atomic chains on the Ge(001)…”
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Structural Biochemistry of ATP-Driven Dimerization and DNA-Stimulated Activation of SMC ATPases by Lammens, Alfred, Schele, Alexandra, Hopfner, Karl-Peter

“…Structural maintenance of chromosome (SMC) proteins play a central role in higher-order chromosome structure in all kingdoms of life [1–5]. SMC proteins…”
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The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair by Petrini, John H. J, Tainer, John A, Hopfner, Karl-Peter, Craig, Lisa, Moncalian, Gabriel, Zinkel, Robert A, Usui, Takehiko, Owen, Barbara A. L, Karcher, Annette, Henderson, Brendan, Bodmer, Jean-Luc, McMurray, Cynthia T, Carney, James P

“…The Mre11 complex (Mre11-Rad50-Nbs1) is central to chromosomal maintenance and functions in homologous recombination, telomere maintenance and sister chromatid…”
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The ternary microplasmin-staphylokinase- microplasmin complex is a proteinase-cofactor- substrate complex in action by Parry, Marina A. A, Bode, Wolfram, Fernandez-Catalan, Carlos, Bergner, Andreas, Huber, Robert, Hopfner, Karl-Peter, Schlott, Bernhard, Gührs, Karl-Heinz

“…The serine proteinase plasmin is the key fibrinolytic enzyme that dissolves blood clots and also promotes cell migration and tissue remodeling. Here, we report…”
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Envisioning the fourth dimension of the genetic code: the structural biology of macromolecular recognition and conformational switching in DNA repair by Hopfner, K P, Parikh, S S, Tainer, J A

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Energetics of the thrombin-fibrinogen interaction by Hopfner, Karl Peter, Di Cera, Enrico

“…The kinetic mechanism of thrombin-fibrinogen interaction has been elucidated by steady-state measurements of synthetic substrate hydrolysis by human…”
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DNA double-strand break repair from head to tail by Hopfner, Karl-Peter, Putnam, Christopher D, Tainer, John A

“…DNA double-strand break repair is a complex process that requires multiple enzymatic and structural activities to rejoin or repair the broken DNA ends using…”
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X-Ray Structure of RLI, an Essential Twin Cassette ABC ATPase Involved in Ribosome Biogenesis and HIV Capsid Assembly by Karcher, Annette, Bu¨ttner, Katharina, Märtens, Birgit, Jansen, Ralf-Peter, Hopfner, Karl-Peter

“…The ABC ATPase RNase-L inhibitor (RLI) emerges as a key enzyme in ribosome biogenesis, formation of translation preinitiation complexes, and assembly of HIV…”
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Crystal Structure of a Thermostable Type B DNA Polymerase from Thermococcus gorgonarius by Hopfner, Karl-Peter, Eichinger, Andreas, Engh, Richard A., Laue, Frank, Ankenbauer, Waltraud, Huber, Robert, Angerer, Bernhard

“…Most known archaeal DNA polymerases belong to the type B family, which also includes the DNA replication polymerases of eukaryotes, but maintain high fidelity…”
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Symmetry Conditions for Binding Processes by Di Cera, Enrico, Hopfner, Karl-Peter, Wyman, Jeffries

“…Symmetry conditions are derived for global and local binding processes in biological macromolecules. It is shown that the conditions applying in the case of…”
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Structural Basis for Transcription-coupled Repair: the N Terminus of Mfd Resembles UvrB with Degenerate ATPase Motifs by Assenmacher, Nora, Wenig, Katja, Lammens, Alfred, Hopfner, Karl-Peter

“…The transcription repair coupling factor Mfd removes stalled RNA polymerase from DNA lesions and links transcription to UvrABC-dependent nucleotide excision…”
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