Search Results - "Hoover, Alyssa"

Increased canonical NF-kappaB signaling specifically in macrophages is sufficient to limit tumor progression in syngeneic murine models of ovarian cancer by Hoover, Alyssa A, Hufnagel, Demetra H, Harris, Whitney, Bullock, Kennady, Glass, Evan B, Liu, Esther, Barham, Whitney, Crispens, Marta A, Khabele, Dineo, Giorgio, Todd D, Wilson, Andrew J, Yull, Fiona E

“…New treatment options for ovarian cancer are urgently required. Tumor-associated macrophages (TAMs) are an attractive target for therapy; repolarizing TAMs…”
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Stimulating TAM-mediated anti-tumor immunity with mannose-decorated nanoparticles in ovarian cancer by Glass, Evan B, Hoover, Alyssa A, Bullock, Kennady K, Madden, Matthew Z, Reinfeld, Bradley I, Harris, Whitney, Parker, Dominique, Hufnagel, Demetra H, Crispens, Marta A, Khabele, Dineo, Rathmell, W Kimryn, Rathmell, Jeffrey C, Wilson, Andrew J, Giorgio, Todd D, Yull, Fiona E

“…Current cancer immunotherapies have made tremendous impacts but generally lack high response rates, especially in ovarian cancer. New therapies are needed to…”
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Abstract TMIM-085: BROMODOMAIN INHIBITION IN OVARIAN CANCER AND THE TUMOR MICROENVIRONMENT by Wilson, Andrew J., Hoover, Alyssa, Harris, Whitney, Liu, Esther, Khabele, Dineo, Yull, Fiona E.

“…Abstract BACKGROUND: Ovarian cancer is the most lethal gynecologic malignancy. While women with BRCA deficient tumors show sensitivity to PARP inhibitors…”
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Abstract 4138: Understanding the effects of NF-kappaB signaling on macrophage phenotype to inform therapeutic approaches by Glass, Evan B., Hoover, Alyssa, Harris, Whitney, Mirafzali, Zahra, Giorgio, Todd D., Wilson, Andrew, Yull, Fiona

“…Abstract It is recognized that modulation of macrophage phenotypes within the tumor microenvironment has the potential to achieve anti-tumor outcomes. However,…”
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Abstract 2728: Modulation of NFkappaB signaling influences tumor associated macrophage phenotypes in murine models of breast cancer by Bullock, Kennady K., Parker, Dominique, Glass, Evan B., Hoover, Alyssa, Merkel, Alyssa, Maynard, Richard, Wilson, Andrew, Giorgio, Todd, Rhoades, Julie A., Yull, Fiona E.

“…Abstract Tumor associated macrophages (TAMs) often exist in high densities in breast tumors and are associated with adverse clinical outcomes. TAM…”
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Abstract 626: Bromodomain inhibition in ovarian cancer and the tumor microenvironment to improve PARP inhibitor response by Wilson, Andrew J., Hoover, Alyssa, Harris, Whitney, Liu, Esther, Khabele, Dineo, Yull, Fiona

“…Abstract Background: Ovarian cancer is the most lethal gynecologic malignancy. While women with BRCA-deficient tumors show sensitivity to PARP inhibitors…”
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Alpha-1 Antitrypsin Deficiency in a Young Never Smoker With Novel PiNull Homozygous Mutation: a Case Report by Barjaktarevic, Igor Z, Hong, Andrew W, Hoover, Alyssa, Nelson, Stanley, Isse, Said, Yoon, Se, Brantley, Mark

“…Alpha-1 antitrypsin deficiency is an autosomal codominant disorder caused by gene mutations. PI*Z and PI*S mutations commonly underlie this deficiency, but…”
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Abstract 4711: Modulation of NFκ-B signaling to optimize antitumor characteristics in macrophages by Liu, Esther, Hoover, Alyssa A., Harris, Whitney R., Barham, Whitney, Tikhomirov, Oleg, Khabele, Dineo, Mirafzahli, Zahra, Giorgio, Todd D., Wilson, Andrew J., Yull, Fiona E.

“…Abstract While it is known that nuclear factor κ-B (NF-κB) signaling within macrophages regulates expression of downstream targets that can mediate either pro-…”
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Abstract 6375: Genetic testing station increases access to germline genetic testing by Hamilton, Camille, Swiller, Mariana Niell, Bhansali, Franceska, Hoover, Alyssa, Bottomley, Stephanie, Lewis, Marisa, Russell, Bianca, Martinez, Julian A., Karlan, Beth, Federman, Noah, Chang, Vivian Y.

“…Abstract Despite evidence of clear benefit, genetic testing of pediatric oncology patients for germline variants remains rare due to a variety of factors,…”
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