Search Results - "Hoots, Keith"
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CCR5AS lncRNA variation differentially regulates CCR5, influencing HIV disease outcome
Published in Nature immunology (01-07-2019)“…Multiple genome-wide studies have identified associations between outcome of human immunodeficiency virus (HIV) infection and polymorphisms in and around the…”
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2
IL28B Polymorphism Does Not Determine Outcomes of Hepatitis B Virus or HIV Infection
Published in The Journal of infectious diseases (01-12-2010)“…An IL28B haplotype strongly determines the outcome of natural and interferon-α treated hepatitis C virus (HCV) infection. To assess whether the polymorphism…”
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3
Role of prothrombin complex concentrates in reversing warfarin anticoagulation: A review of the literature
Published in American journal of hematology (01-02-2008)“…Over‐anticoagulation is a common problem with warfarin therapy and can lead to major or life‐threatening bleeding. The goal of urgent warfarin reversal is to…”
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4
Zika virus: a new threat to the safety of the blood supply with worldwide impact and implications
Published in Transfusion (Philadelphia, Pa.) (01-07-2016)Get full text
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5
A Novel Variant Marking HLA-DP Expression Levels Predicts Recovery from Hepatitis B Virus Infection
Published in Journal of Virology (01-06-2012)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Executive summary of the NHLBI State of the Science (SOS) Workshop: Overview and next steps in generating a national blueprint for future research on factor VIII inhibitors
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-07-2019)Get full text
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VWF mutations and new sequence variations identified in healthy controls are more frequent in the African-American population
Published in Blood (01-03-2012)“…Diagnosis and classification of VWD is aided by molecular analysis of the VWF gene. Because VWF polymorphisms have not been fully characterized, we performed…”
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The importance of genetic factors for the development of arthropathy: a longitudinal study of children and adolescents with haemophilia A
Published in Thrombosis and haemostasis (2017)“…Haemophilia A is a congenital bleeding disorder characterised by recurrent haemorrhages into the major joints. Haemophilic arthropathy is a well-established…”
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9
Clinical issues in inhibitors
Published in Haemophilia : the official journal of the World Federation of Hemophilia (01-07-2010)“…Anamestic inhibitors represent the major complication of haemophilia therapy now that clotting factor concentrates are virtually free of pathogen‐transmission…”
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Citation Impact of NHLBI R01 Grants Funded Through the American Recovery and Reinvestment Act as Compared to R01 Grants Funded Through a Standard Payline
Published in Circulation research (27-02-2015)“…RATIONALE:The American Recovery and Reinvestment Act (ARRA) allowed National Heart, Lung, and Blood Institute to fund R01 grants that fared less well on peer…”
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Epistatic interaction between KIR3DS1 and HLA-B delays the progression to AIDS
Published in Nature genetics (01-08-2002)“…Natural killer (NK) cells provide defense in the early stages of the innate immune response against viral infections by producing cytokines and causing…”
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The National Heart, Lung, and Blood Institute Strategic Vision Implementation for Health Equity Research
Published in Ethnicity & disease (21-02-2019)“…The National Heart, Lung, and Blood Institute (NHLBI) provides global leadership for a research, training, and education program to promote the prevention and…”
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Author Correction: CCR5AS lncRNA variation differentially regulates CCR5, influencing HIV disease outcome
Published in Nature immunology (01-11-2019)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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14
On the Value of Portfolio Diversity in Heart, Lung, and Blood Research
Published in Circulation research (14-09-2012)Get full text
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15
Haemostatic efficacy and safety of bolus and continuous infusion of recombinant factor VIIa are comparable in haemophilia patients with inhibitors undergoing major surgery. Results from an open-label, randomized, multicenter trial
Published in Thrombosis and haemostasis (01-10-2007)“…Bolus infusion (BI) recombinant factor VIIa (rFVIIa) administration is safe and effective in the surgical management of haemophilia patients with inhibitors…”
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16
AIDS restriction HLA allotypes target distinct intervals of HIV-1 pathogenesis
Published in Nature medicine (01-12-2005)“…An effective acquired immune response to infectious agents mediated by HLA-restricted T-cell recognition can target different stages of disease pathogenesis…”
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Evidence for the benefits of prophylaxis in the management of hemophilia A
Published in Thrombosis and haemostasis (01-10-2006)“…The optimal treatment of hemophilia has been evolving since the advent of factor VIII concentrates, continues to vary geographically, and remains a source of…”
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18
Large-Scale Candidate Gene Analysis of Spontaneous Clearance of Hepatitis C Virus
Published in The Journal of infectious diseases (01-05-2010)“…Human genetic variation is a determinant of recovery from acute hepatitis C virus (HCV) infection; however, to date, single-nucleotide polymorphisms (SNPs) in…”
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19
Effect of a Single Amino Acid Change in MHC Class I Molecules on the Rate of Progression to AIDS
Published in The New England journal of medicine (31-05-2001)“…A single amino acid substitution in HLA molecules has a substantial effect on the rate of progression from HIV-1 infection to AIDS. HLA class I molecules…”
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Association of DC-SIGN Promoter Polymorphism with Increased Risk for Parenteral, but Not Mucosal, Acquisition of Human Immunodeficiency Virus Type 1 Infection
Published in Journal of Virology (01-12-2004)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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