Search Results - "Hooshdaran, Nima"

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    p53 Activates the Long Noncoding RNA Pvt1b to Inhibit Myc and Suppress Tumorigenesis by Olivero, Christiane E., Martínez-Terroba, Elena, Zimmer, Joshua, Liao, Clara, Tesfaye, Ephrath, Hooshdaran, Nima, Schofield, Jeremy A., Bendor, Jordan, Fang, Dorthy, Simon, Matthew D., Zamudio, Jesse R., Dimitrova, Nadya

    Published in Molecular cell (20-02-2020)
    “…The tumor suppressor p53 transcriptionally activates target genes to suppress cellular proliferation during stress. p53 has also been implicated in the…”
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    Journal Article
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    Temporal Control of the TGF-β Signaling Network by Mouse ESC MicroRNA Targets of Different Affinities by Kelly, Timothy J., Brümmer, Anneke, Hooshdaran, Nima, Tariveranmoshabad, Mito, Zamudio, Jesse R.

    Published in Cell reports (Cambridge) (26-11-2019)
    “…Although microRNAs (miRNAs) function in the control of embryonic stem cell (ESC) pluripotency, a systems-level understanding is still being developed. Through…”
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  4. 4

    Elevated labile iron in castration–resistant prostate cancer is targetable with ferrous iron–activatable antiandrogen therapy by Gonciarz, Ryan L., Sakhamuri, Sasank, Hooshdaran, Nima, Kumar, Garima, Kim, Hyunjung, Evans, Michael J., Renslo, Adam R.

    Published in European journal of medicinal chemistry (05-03-2023)
    “…Clinical responses to second generation androgen signaling inhibitors (e.g., enzalutamide) in metastatic castration-resistant prostate cancer (mCRPC) are…”
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  5. 5

    Ferronostics: Measuring Tumoral Ferrous Iron with PET to Predict Sensitivity to Iron-Targeted Cancer Therapies by Zhao, Ning, Huang, Yangjie, Wang, Yung-Hua, Muir, Ryan K, Chen, Ying-Chu, Wei, Junnian, Hooshdaran, Nima, Viswanath, Pavithra, Seo, Youngho, Ruggero, Davide, Renslo, Adam R, Evans, Michael J

    Published in Journal of Nuclear Medicine (01-07-2021)
    “…Although cancer has been known for decades to harbor an insatiable appetite for iron, only recently has the chemistry emerged to exploit this altered state…”
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  6. 6

    In Vivo Profiling with 18F‑YJH08 Reveals Diverse Tissue Patterns of Antagonist/Glucocorticoid Receptor Interactions by Kim, Hyunjung, Huang, Yangjie, Zhao, Ning, Wang, Yung-hua, Sakhamuri, Sasank, Chopra, Shalini, Hooshdaran, Nima, Sriram, Renuka, Aggarwal, Rahul, Evans, Michael J

    Published in Molecular pharmaceutics (07-02-2022)
    “…Demonstrating target engagement in vivo is an important milestone in drug development, both to establish on target, on tissue interactions but also to identify…”
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  7. 7

    In Vivo Profiling with 18 F-YJH08 Reveals Diverse Tissue Patterns of Antagonist/Glucocorticoid Receptor Interactions by Kim, Hyunjung, Huang, Yangjie, Zhao, Ning, Wang, Yung-Hua, Sakhamuri, Sasank, Chopra, Shalini, Hooshdaran, Nima, Sriram, Renuka, Aggarwal, Rahul, Evans, Michael J

    Published in Molecular pharmaceutics (07-02-2022)
    “…Demonstrating target engagement in vivo is an important milestone in drug development, both to establish on target, on tissue interactions but also to identify…”
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    Journal Article
  8. 8

    Theranostic Targeting of CUB Domain-Containing Protein 1 (CDCP1) in Multiple Subtypes of Bladder Cancer by Chopra, Shalini, Trepka, Kai, Sakhamuri, Sasank, Carretero-González, Alberto, Zhu, Jun, Egusa, Emily, Zhou, Jie, Leung, Kevin, Zhao, Ning, Hooshdaran, Nima, Feng, Felix Y, Wells, James A, Chou, Jonathan, Evans, Michael J

    Published in Clinical cancer research (03-04-2023)
    “…Despite recent approvals for checkpoint inhibitors and antibody-drug conjugates targeting NECTIN4 or TROP2, metastatic bladder cancer remains incurable and new…”
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