Search Results - "Hoos, Michael"

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  1. 1

    Reduced Levels of Cerebrospinal Fluid/Plasma Aβ40 as an Early Biomarker for Cerebral Amyloid Angiopathy in RTg-DI Rats by Zhu, Xiaoyue, Xu, Feng, Hoos, Michael D, Lee, Hedok, Benveniste, Helene, Nostrand, William E Van

    “…The accumulation of fibrillar amyloid β-protein (Aβ) in blood vessels of the brain, the condition known as cerebral amyloid angiopathy (CAA), is a common small…”
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    Journal Article
  2. 2

    A Novel Transgenic Rat Model of Robust Cerebral Microvascular Amyloid with Prominent Vasculopathy by Davis, Judianne, Xu, Feng, Hatfield, Joshua, Lee, Hedok, Hoos, Michael D., Popescu, Dominique, Crooks, Elliot, Kim, Regina, Smith, Steven O., Robinson, John K., Benveniste, Helene, Van Nostrand, William E.

    Published in The American journal of pathology (01-12-2018)
    “…Accumulation of fibrillar amyloid β protein in blood vessels of the brain, a condition known as cerebral amyloid angiopathy (CAA), is a common pathology of…”
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    Journal Article
  3. 3

    Longitudinal Study of Differential Protein Expression in an Alzheimer’s Mouse Model Lacking Inducible Nitric Oxide Synthase by Hoos, Michael D, Richardson, Brenna M, Foster, Matthew W, Everhart, Angela, Thompson, J. Will, Moseley, M. Arthur, Colton, Carol A

    Published in Journal of proteome research (04-10-2013)
    “…Alzheimer’s disease (AD) is a complex neurodegenerative process that involves altered brain immune, neuronal and metabolic functions. Understanding the…”
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    Journal Article
  4. 4

    Fine Mapping of the Amyloid β‑Protein Binding Site on Myelin Basic Protein by Kotarba, AnnMarie E, Aucoin, Darryl, Hoos, Michael D, Smith, Steven O, Van Nostrand, William E

    Published in Biochemistry (Easton) (16-04-2013)
    “…The assembly and deposition of amyloid β-protein (Aβ) in brain is a key pathological feature of Alzheimer’s disease and related disorders. Factors have been…”
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    Journal Article
  5. 5

    The impact of human and mouse differences in NOS2 gene expression on the brain's redox and immune environment by Hoos, Michael D, Vitek, Michael P, Ridnour, Lisa A, Wilson, Joan, Jansen, Marilyn, Everhart, Angela, Wink, David A, Colton, Carol A

    Published in Molecular neurodegeneration (17-11-2014)
    “…Mouse models are used in the study of human disease. Despite well-known homologies, the difference in immune response between mice and humans impacts the…”
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    Journal Article
  6. 6

    N-terminal Domain of Myelin Basic Protein Inhibits Amyloid β-Protein Fibril Assembly by Liao, Mei-Chen, Hoos, Michael D., Aucoin, Darryl, Ahmed, Mahiuddin, Davis, Judianne, Smith, Steven O., Van Nostrand, William E.

    Published in The Journal of biological chemistry (12-11-2010)
    “…Accumulation of amyloid β-protein (Aβ) into brain parenchymal plaques and the cerebral vasculature is a pathological feature of Alzheimer disease and related…”
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    Journal Article
  7. 7

    Myelin Basic Protein Binds to and Inhibits the Fibrillar Assembly of Aβ42 in Vitro by Hoos, Michael D, Ahmed, Mahiuddin, Smith, Steven O, Van Nostrand, William E

    Published in Biochemistry (Easton) (09-06-2009)
    “…The deposition of amyloid β-protein (Aβ) fibrils into plaques within the brain parenchyma and along cerebral blood vessels is a hallmark of Alzheimer’s…”
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    Journal Article
  8. 8

    Inhibition of Familial Cerebral Amyloid Angiopathy Mutant Amyloid β-Protein Fibril Assembly by Myelin Basic Protein by Hoos, Michael D., Ahmed, Mahiuddin, Smith, Steven O., Van Nostrand, William E.

    Published in The Journal of biological chemistry (30-03-2007)
    “…Deposition of fibrillar amyloid β-protein (Aβ) in the brain is a prominent pathological feature of Alzheimer disease and related disorders, including familial…”
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    Journal Article
  9. 9

    Mutation of the Kunitz-type proteinase inhibitor domain in the amyloid β-protein precursor abolishes its anti-thrombotic properties in vivo by Xu, Feng, Davis, Judianne, Hoos, Michael, Van Nostrand, William E

    Published in Thrombosis research (01-07-2017)
    “…Abstract Introduction Kunitz proteinase inhibitor (KPI) domain-containing forms of the amyloid β-protein precursor (AβPP) inhibit cerebral thrombosis. KPI…”
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    Journal Article
  10. 10
  11. 11

    Nitric oxide-mediated regulation of β-amyloid clearance via alterations of MMP-9/TIMP-1 by Ridnour, Lisa A., Dhanapal, Sneha, Hoos, Michael, Wilson, Joan, Lee, Jennifer, Cheng, Robert Y. S., Brueggemann, Ernst E., Hines, Harry B., Wilcock, Donna M., Vitek, Michael P., Wink, David A., Colton, Carol A.

    Published in Journal of neurochemistry (01-12-2012)
    “…Fibrillar amyloid plaques are largely composed of amyloid‐beta (Aβ) peptides that are metabolized into products, including Aβ1‐16, by proteases including…”
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    Journal Article
  12. 12
  13. 13

    N-terminal Domain of Myelin Basic Protein Inhibits Amyloid b-Protein Fibril Assembly by Liao, Mei-Chen, Hoos, Michael D, Aucoin, Darryl, Ahmed, Mahiuddin, Davis, Judianne, Smith, Steven O, Van Nostrand, William E

    Published in The Journal of biological chemistry (01-11-2010)
    “…Accumulation of amyloid b-protein (Ab) into brain parenchymal plaques and the cerebral vasculature is a pathological feature of Alzheimer disease and related…”
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    Journal Article
  14. 14

    Myelin Basic Protein Binds to and Inhibits the Fibrillar Assembly of Ab42 in Vitro by Hoos, Michael D, Ahmed, Mahiuddin, Smith, Steven O, Van Nostrand, William E

    Published in Biochemistry (Easton) (22-04-2009)
    “…The deposition of amyloid *b-protein (A*b) fibrils into plaques within the brain parenchyma and along cerebral blood vessels is a hallmark of Alzheimer's…”
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    Journal Article
  15. 15

    Nitric oxide‐mediated regulation of ‐amyloid clearance via alterations of MMP ‐9/ TIMP ‐1 by Ridnour, Lisa A., Dhanapal, Sneha, Hoos, Michael, Wilson, Joan, Lee, Jennifer, Cheng, Robert Y. S., Brueggemann, Ernst E., Hines, Harry B., Wilcock, Donna M., Vitek, Michael P., Wink, David A., Colton, Carol A.

    Published in Journal of neurochemistry (01-12-2012)
    “…Abstract Fibrillar amyloid plaques are largely composed of amyloid‐beta (Aβ) peptides that are metabolized into products, including Aβ1‐16, by proteases…”
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    Journal Article
  16. 16
  17. 17

    Inhibition of amyloid beta-protein fibrillogenesis by myelin basic protein by Hoos, Michael David

    Published 01-01-2009
    “…Deposition of fibrillar amyloid β-protein (Aβ) in the brain is a prominent pathological feature of Alzheimer disease (AD) and related disorders, including…”
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    Dissertation
  18. 18

    Myelin basic protein binds to and inhibits the fibrillar assembly of Abeta42 in vitro by Hoos, Michael D, Ahmed, Mahiuddin, Smith, Steven O, Van Nostrand, William E

    Published in Biochemistry (Easton) (09-06-2009)
    “…The deposition of amyloid beta-protein (Abeta) fibrils into plaques within the brain parenchyma and along cerebral blood vessels is a hallmark of Alzheimer's…”
    Get full text
    Journal Article
  19. 19

    Inhibition of Familial Cerebral Amyloid Angiopathy Mutant Amyloid β-Protein Fibril Assembly by Myelin Basic Protein by Michael D. Hoos, Mahiuddin Ahmed, Steven O. Smith, William E. Van Nostrand

    Published in The Journal of biological chemistry (30-03-2007)
    “…Deposition of fibrillar amyloid β-protein (Aβ) in the brain is a prominent pathological feature of Alzheimer disease and related disorders, including…”
    Get full text
    Journal Article