Search Results - "Hooper, J D"

Elevated CDCP1 predicts poor patient outcome and mediates ovarian clear cell carcinoma by promoting tumor spheroid formation, cell migration and chemoresistance by He, Y, Wu, A C, Harrington, B S, Davies, C M, Wallace, S J, Adams, M N, Palmer, J S, Roche, D K, Hollier, B G, Westbrook, T F, Hamidi, H, Konecny, G E, Winterhoff, B, Chetty, N P, Crandon, A J, Oliveira, N B, Shannon, C M, Tinker, A V, Gilks, C B, Coward, J I, Lumley, J W, Perrin, L C, Armes, J E, Hooper, J D

“…Hematogenous metastases are rarely present at diagnosis of ovarian clear cell carcinoma (OCC). Instead dissemination of these tumors is characteristically via…”
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EGF inhibits constitutive internalization and palmitoylation-dependent degradation of membrane-spanning procancer CDCP1 promoting its availability on the cell surface by Adams, M N, Harrington, B S, He, Y, Davies, C M, Wallace, S J, Chetty, N P, Crandon, A J, Oliveira, N B, Shannon, C M, Coward, J I, Lumley, J W, Perrin, L C, Armes, J E, Hooper, J D

“…Many cancers are dependent on inappropriate activation of epidermal growth factor receptor (EGFR), and drugs targeting this receptor can improve patient…”
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Stratum basale keratinocyte expression of the cell-surface glycoprotein CDCP1 during epidermogenesis and its role in keratinocyte migration by McGovern, J.A., Heinemann, J.R., Burke, L.J., Dawson, R., Parker, T.J., Upton, Z., Hooper, J.D., Manton, K.J.

“…Summary Background  Epidermogenesis and epidermal wound healing are tightly regulated processes during which keratinocytes must migrate, proliferate and…”
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MUC13 protects colorectal cancer cells from death by activating the NF-κB pathway and is a potential therapeutic target by Sheng, Y H, He, Y, Hasnain, S Z, Wang, R, Tong, H, Clarke, D T, Lourie, R, Oancea, I, Wong, K Y, Lumley, J W, Florin, T H, Sutton, P, Hooper, J D, McMillan, N A, McGuckin, M A

“…MUC13 is a transmembrane mucin glycoprotein that is over produced by many cancers, although its functions are not fully understood. Nuclear factor-κB (NF-κB)…”
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Blocking of CDCP1 cleavage in vivo prevents Akt-dependent survival and inhibits metastatic colonization through PARP1-mediated apoptosis of cancer cells by Casar, B, He, Y, Iconomou, M, Hooper, J D, Quigley, J P, Deryugina, E I

“…The CUB domain-containing protein-1 (CDCP1) is a transmembrane molecule that has recently been implicated in cancer progression. In this study we have…”
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Reynolds stress, mean velocity, and dynamic static pressure measurement by a four-hole pressure probe by Hooper, J.D., Musgrove, A.R.

“…An improved version of the four-hole directional pressure probe, or Cobra probe, is described, in which the frequency response has been extended to 1.5 kHz…”
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Protease-activated receptor-2 promotes osteogenesis in skeletal mesenchymal stem cells at the expense of adipogenesis: Involvement of interleukin-6 by Sanaei, R., Kularathna, P.K., Taghavi, N., Hooper, J.D., Pagel, C.N., Mackie, E.J.

“…Bone marrow mesenchymal stem cells (MSCs) give rise to osteoblasts and adipocytes, with an inverse relationship between the two. The MSCs from…”
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Mapping transmembrane residues of proteinase activated receptor 2 (PAR2) that influence ligand-modulated calcium signaling by Suen, J.Y., Adams, M.N., Lim, J., Madala, P.K., Xu, W., Cotterell, A.J., He, Y., Yau, M.K., Hooper, J.D., Fairlie, D.P.

“…[Display omitted] Proteinase-activated receptor 2 (PAR2) is a G protein-coupled receptor involved in metabolism, inflammation, and cancers. It is activated by…”
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Testisin, a new human serine proteinase expressed by premeiotic testicular germ cells and lost in testicular germ cell tumors by HOOPER, J. D, NICOL, D. L, ANTALIS, T. M, DICKINSON, J. L, EYRE, H. J, SCARMAN, A. L, NORMYLE, J. F, STUTTGEN, M. A, DOUGLAS, M. L, LOVELAND, K. A. L, SUTHERLAND, G. R

“…We have cloned and characterized a cDNA encoding a new human serine proteinase, testisin, that is abundantly expressed only in the testis and is lost in…”
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Type II transmembrane serine proteases. Insights into an emerging class of cell surface proteolytic enzymes by Hooper, J D, Clements, J A, Quigley, J P, Antalis, T M

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Velocity and Reynolds stresses in a precessing jet flow by SCHNEIDER, G. M, HOOPER, J. D, MUSGROVE, A. R, NATHAN, G. J, LUXTON, R. E

“…A novel fluid mixing device, described elsewhere, has been shown to have a dramatic effect on the combustion characteristics of a fuel jet. The main features…”
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Subtractive immunization using highly metastatic human tumor cells identifies SIMA135 CDCP1, a 135 kDa cell surface phosphorylated glycoprotein antigen by HOOPER, John D, ZIJLSTRA, Andries, AIMES, Ronald T, HONGYAN LIANG, CLAASSEN, Gisela F, TARIN, David, TESTA, Jacqueline E, QUIGLEY, James P

“…We have previously used a subtractive immunization (SI) approach to generate monoclonal antibodies (mAbs) against proteins preferentially expressed by the…”
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Tissue-specific Expression Patterns and Fine Mapping of the Human Kallikrein (KLK) Locus on Proximal 19q13.4 by Harvey, Tracey J., Hooper, John D., Myers, Stephen A., Stephenson, Sally-Anne, Ashworth, Linda K., Clements, Judith A.

“…The tissue or glandular kallikreins (KLK) are members of a highly conserved multigene family encoding serine proteases that are central to many biological…”
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Differentiation of species and populations of Aphelenchoides and of Ditylenchus angustus using a fragment of ribosomal DNA by Ibrahim, S.K. (IACR, Harpenden, Hertfordshire, UK.), Perry, R.N, Burrows, P.R, Hooper, D.J

“…The polymerase chain reaction (PCR) was used to amplify a fragment of the ribosomal DNA (rDNA) from species and undescribed populations of Aphelenchoides and…”
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Characterization of a novel gene, STAG1/PMEPA1, upregulated in renal cell carcinoma and other solid tumors by Rae, Fiona K., Hooper, John D., Nicol, David L., Clements, Judith A.

“…Using differential display–polymerase chain reaction, we identified a novel gene sequence, designated solid tumor–associated gene 1 (STAG1), that is…”
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Identification and Characterization of KLK14, a Novel Kallikrein Serine Protease Gene Located on Human Chromosome 19q13.4 and Expressed in Prostate and Skeletal Muscle by Hooper, John D., Bui, Loan T., Rae, Fiona K., Harvey, Tracey J., Myers, Stephen A., Ashworth, Linda K., Clements, Judith A.

“…The kallikreins are a subfamily of serine proteases encoded in human, mouse, and rat by highly conserved tightly clustered multigene families. Here we report…”
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TTYH2, a Human Homologue of the Drosophila melanogaster Gene tweety, Is Located on 17q24 and Upregulated in Renal Cell Carcinoma by Rae, Fiona K, Hooper, John D, Eyre, Helen J, Sutherland, Grant R, Nicol, David L, Clements, Judith A

“…Using differential display PCR, we identified a novel gene upregulated in renal cell carcinoma. Characterization of the full-length cDNA and gene revealed that…”
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Evaluating and upgrading welded steel moment-frame buildings using FEMA-351 by Hooper, John D

“…In July 2000, the SAC Joint Venture (a joint venture of the Structural Engineers Association of California, the Applied Technology Council, and California…”
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Localization of the mosaic transmembrane serine protease corin to heart myocytes by Hooper, John D., Scarman, Anthony L., Clarke, Belinda E., Normyle, John F., Antalis, Toni M.

“…Corin cDNA encodes an unusual mosaic type II transmembrane serine protease, which possesses, in addition to a trypsin‐like serine protease domain, two frizzled…”
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Cloning of the cDNA and Localization of the Gene Encoding Human NRBP, a Ubiquitously Expressed, Multidomain Putative Adapter Protein by Hooper, John D., Baker, Elizabeth, Ogbourne, Steven M., Sutherland, Grant R., Antalis, Toni M.

“…Adapter proteins modulate multiple signaling pathways by regulating the aggregation of other factors into signaling complexes. Here we have identified a novel…”
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