Search Results - "Hoon, D"

Founder affiliations: jobseeker reactions and impact on employee recruitment by start-up ventures by Chung, Seung Hoon D., Parker, Simon C.

“…Many entrepreneurs face challenges in hiring employees, in part because of information asymmetries between start-ups and jobseekers. This paper argues that the…”
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Assessment of DNA methylation status in early stages of breast cancer development by van Hoesel, A Q, Sato, Y, Elashoff, D A, Turner, R R, Giuliano, A E, Shamonki, J M, Kuppen, P J K, van de Velde, C J H, Hoon, D S B

“…Background: Molecular pathways determining the malignant potential of premalignant breast lesions remain unknown. In this study, alterations in DNA methylation…”
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Epigenetic status of LINE-1 predicts clinical outcome in early-stage rectal cancer by Benard, A, van de Velde, C J H, Lessard, L, Putter, H, Takeshima, L, Kuppen, P J K, Hoon, D S B

“…Background: We evaluated the clinical prognostic value of methylation of two non-coding repeat sequences, long interspersed element 1 (LINE-1) and Alu, in…”
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Lentivirus-induced ‘Smart’ dendritic cells: Pharmacodynamics and GMP-compliant production for immunotherapy against TRP2-positive melanoma by Sundarasetty, B S, Chan, L, Darling, D, Giunti, G, Farzaneh, F, Schenck, F, Naundorf, S, Kuehlcke, K, Ruggiero, E, Schmidt, M, von Kalle, C, Rothe, M, Hoon, D S B, Gerasch, L, Figueiredo, C, Koehl, U, Blasczyk, R, Gutzmer, R, Stripecke, R

“…Monocyte-derived conventional dendritic cells (ConvDCs) loaded with melanoma antigens showed modest responses in clinical trials. Efficacy studies were…”
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Functional RET G691S polymorphism in cutaneous malignant melanoma by Narita, N, Tanemura, A, Murali, R, Scolyer, R A, Huang, S, Arigami, T, Yanagita, S, Chong, K K, Thompson, J F, Morton, D L, Hoon, D S

“…RET proto-oncogene encodes a receptor tyrosine kinase whose ligand is glial cell line-derived neurotrophic factor (GDNF), and its polymorphism at G691S…”
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BAG3 protein expression in melanoma metastatic lymph nodes correlates with patients’ survival by Guerriero, L, Chong, K, Franco, R, Rosati, A, De Caro, F, Capunzo, M, Turco, M C, Hoon, D SB

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Transcriptional repression of IFNβ1 by ATF2 confers melanoma resistance to therapy by Lau, E, Sedy, J, Sander, C, Shaw, M A, Feng, Y, Scortegagna, M, Claps, G, Robinson, S, Cheng, P, Srivas, R, Soonthornvacharin, S, Ideker, T, Bosenberg, M, Gonzalez, R, Robinson, W, Chanda, S K, Ware, C, Dummer, R, Hoon, D, Kirkwood, J M, Ronai, Z A

“…The resistance of melanoma to current treatment modalities represents a major obstacle for durable therapeutic response, and thus the elucidation of mechanisms…”
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Unfavourable prognosis associated with K-ras gene mutation in pancreatic cancer surgical margins by Kim, J, Reber, H A, Dry, S M, Elashoff, D, Chen, S L, Umetani, N, Kitago, M, Hines, O J, Kazanjian, K K, Hiramatsu, S, Bilchik, A J, Yong, S, Shoup, M, Hoon, D S B

“…Background: Despite intent to cure surgery with negative resection margins, locoregional recurrence is common in pancreatic cancer. Aims: To determine whether…”
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Transcriptional repression of IFN beta 1 by ATF2 confers melanoma resistance to therapy by Lau, E, Sedy, J, Sander, C, Shaw, M A, Feng, Y, Scortegagna, M, Claps, G, Robinson, S, Cheng, P, Srivas, R, Soonthornvacharin, S, Ideker, T, Bosenberg, M, Gonzalez, R, Robinson, W, Chanda, S K, Ware, C, Dummer, R, Hoon, D, Kirkwood, J M, Ronai, Z A

“…The resistance of melanoma to current treatment modalities represents a major obstacle for durable therapeutic response, and thus the elucidation of mechanisms…”
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Aberrant hypermethylation in primary tumours and sentinel lymph node metastases in paediatric patients with cutaneous melanoma by Huynh, K.T., Takei, Y., Kuo, C., Scolyer, R.A., Murali, R., Chong, K., Takeshima, L., Sim, M-S., Morton, D.L., Turner, R.R., Thompson, J.F., Hoon, D.S.B.

“…Summary Background  Debate on how to manage paediatric patients with cutaneous melanoma continues, particularly in those with sentinel lymph node (SLN)…”
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Molecular analysis of sentinel lymph nodes and search for molecular signatures of the metastatic potential of breast cancer by Hoon, D S, Bernet, L, Cano, R, Viale, G

“…Molecular assays are a new and invaluable tool in the assessment of axillary lymph node status and metastatic potential of breast cancer. Many protocols for…”
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Limitations of specific reverse-transcriptase polymerase chain reaction markers in the detection of metastases in the lymph nodes and blood of breast cancer patients by Bostick, P J, Chatterjee, S, Chi, D D, Huynh, K T, Giuliano, A E, Cote, R, Hoon, D S

“…This study was performed to evaluate the potential of specific mRNA markers to detect micrometastases by reverse-transcriptase polymerase chain reaction…”
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Immunity against breast cancer by TERT DNA vaccine primed with chemokine CCL21 by Yamano, T, Kaneda, Y, Hiramatsu, S H, Huang, S, Tran, A N, Giuliano, A E, Hoon, D S B

“…Human telomerase reverse transcriptase (TERT) has been considered a potential tumor-associated antigen for active-specific immunotherapy. However, effective…”
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EMR versus gastrectomy for intramucosal gastric cancer: comparison of long-term outcomes by Choi, Kwi-Sook, MD, PhD, Jung, Hwoon-Yong, MD, PhD, AGAF, Choi, Kee Don, MD, PhD, Lee, Gin Hyug, MD, PhD, Song, Ho June, MD, PhD, Kim, Do Hoon, MD, Lee, Jeong Hoon, MD, Kim, Mi-Young, MD, Kim, Byung Sik, MD, PhD, Oh, Sung Tae, MD, PhD, Yook, Jeong Hwan, MD, PhD, Jang, Se Jin, MD, PhD, Yun, Sung-Cheol, PhD, Kim, Seon Ok, Kim, Jin-Ho, MD, PhD

“…Background Limited data exist regarding the long-term outcomes of EMR compared with gastrectomy. Objective To compare the long-term outcomes after EMR and…”
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Prognostic Significance of Occult Metastases Detected by Sentinel Lymphadenectomy and Reverse Transcriptase–Polymerase Chain Reaction in Early-Stage Melanoma Patients by BOSTICK, P. J, MORTON, D. L, TURNER, R. R, HUYNH, K. T, WANG, H.-J, ELASHOFF, R, ESSNER, R, HOON, D. S. B

“…Detection of micrometastases in the regional tumor-draining lymph nodes is critical for accurate staging and prognosis in melanoma patients. We hypothesized…”
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Detection of occult metastatic breast Cancer cells in blood by a multimolecular marker assay: Correlation with clinical stage of disease by TABACK, Bret, CHAN, Arden D, KUO, Christine T, BOSTICK, Peter J, WANG, He-Jing, GIULIANO, Armando E, HOON, Dave S. B

“…Currently, molecular markers offer the unique opportunity to identify occult metastasis in early stage cancer patients not otherwise detected with conventional…”
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Molecular Staging of Early Colon Cancer on the Basis of Sentinel Node Analysis: A Multicenter Phase II Trial by BILCHIK, Anton J, SAHA, Sukamal, WIESE, David, STONECYPHER, James A, WOOD, Thomas F, SOSTRIN, Stuart, TURNER, Roderick R, WANG, He-Jing, MORTON, Donald L, HOON, Dave S. B

“…Approximately 30% of patients with American Joint Committee on Cancer stage I or II colorectal cancer (CRC) develop systemic disease. We hypothesized that…”
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Molecular markers in blood as surrogate prognostic indicators of melanoma recurrence by HOON, D. S. B, BOSTICK, P, KUO, C, OKAMOTO, T, WANG, H.-J, ELASHOFF, R, MORTON, D. L

“…Improvement is needed in the ability to evaluate the prognosis of melanoma patients who are clinically disease-free but likely to develop recurrent metastatic…”
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Do hepatic-sided tumors require more extensive resection than peritoneal-sided tumors in patients with T2 gallbladder cancer? Results of a retrospective multicenter study by Lee, Woohyung, MD, Jeong, Chi-Young, MD, PhD, Jang, Jae Yool, MD, Kim, Young Hoon, MD, PhD, Roh, Young Hoon, MD, PhD, Kim, Kwan Woo, MD, PhD, Kang, Sung Hwa, MD, Yoon, Myung Hee, MD, PhD, Seo, Hyung Il, MD, PhD, Yun, Sung Pil, MD, Park, Jeong-Ik, MD, PhD, Jung, Bo-Hyun, MD, Shin, Dong Hoon, MD, PhD, Choi, Young Il, MD, Moon, Hyung Hwan, MD, Chu, Chong Woo, MD, PhD, Ryu, Je Ho, MD, Yang, Kwangho, MD, Park, Young Mok, MD, Hong, Soon-Chan, MD, PhD

“…Background Tumor location is a prognostic factor for survival in patients with T2 gallbladder cancer. However, the optimal extent of resection according to…”
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RNA melanoma vaccine: induction of antitumor immunity by human glycoprotein 100 mRNA immunization by Zhou, W Z, Hoon, D S, Huang, S K, Fujii, S, Hashimoto, K, Morishita, R, Kaneda, Y

“…An RNA melanoma vaccine was investigated to induce protective immunity in a mouse-melanoma model. LacZ mRNA was synthesized in vitro by pSFV3 expression vector…”
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