Search Results - "Hookway, Edward S."

Inhibition of histone H3K27 demethylases selectively modulates inflammatory phenotypes of natural killer cells by Cribbs, Adam, Hookway, Edward S., Wells, Graham, Lindow, Morten, Obad, Susanna, Oerum, Henrik, Prinjha, Rab K., Athanasou, Nick, Sowman, Aneka, Philpott, Martin, Penn, Henry, Soderstrom, Kalle, Feldmann, Marc, Oppermann, Udo

“…Natural killer (NK) cells are innate lymphocytes, important in immune surveillance and elimination of stressed, transformed, or virus-infected cells. They…”
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Synovial chondromatosis and soft tissue chondroma: extraosseous cartilaginous tumor defined by FN1 gene rearrangement by Amary, Fernanda, Perez-Casanova, Luis, Ye, Hongtao, Cottone, Lucia, Strobl, Anna-Christina, Cool, Paul, Miranda, Elena, Berisha, Fitim, Aston, William, Rocha, Maia, O’Donnell, Paul, Pillay, Nischalan, Tirabosco, Roberto, Baumhoer, Daniel, Hookway, Edward S., Flanagan, Adrienne M.

“…A fusion between fibronectin 1 ( FN1 ) and activin receptor 2A ( ACVR2A ) has been reported previously in isolated cases of the synovial chondromatosis. To…”
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Structural analysis of human KDM5B guides histone demethylase inhibitor development by Johansson, Catrine, Velupillai, Srikannathasan, Tumber, Anthony, Szykowska, Aleksandra, Hookway, Edward S, Nowak, Radoslaw P, Strain-Damerell, Claire, Gileadi, Carina, Philpott, Martin, Burgess-Brown, Nicola, Wu, Na, Kopec, Jola, Nuzzi, Andrea, Steuber, Holger, Egner, Ursula, Badock, Volker, Munro, Shonagh, LaThangue, Nicholas B, Westaway, Sue, Brown, Jack, Athanasou, Nick, Prinjha, Rab, Brennan, Paul E, Oppermann, Udo

“…X-ray crystallographic analyses of KDM5B provide a view of the enzyme's iron( II )- and 2-oxoglutarate-containing catalytic core, and structures of KDM5B…”
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Linker Histone H1.2 Directs Genome-wide Chromatin Association of the Retinoblastoma Tumor Suppressor Protein and Facilitates Its Function by Munro, Shonagh, Hookway, Edward S., Floderer, Melanie, Carr, Simon M., Konietzny, Rebecca, Kessler, Benedikt M., Oppermann, Udo, La Thangue, Nicholas B.

“…The retinoblastoma tumor suppressor protein pRb is a master regulator of cellular proliferation, principally through interaction with E2F and regulation of E2F…”
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Inhibition of Histone H3K27 Demethylases Inactivates Brachyury (TBXT) and Promotes Chordoma Cell Death by Cottone, Lucia, Cribbs, Adam P, Khandelwal, Garima, Wells, Graham, Ligammari, Lorena, Philpott, Martin, Tumber, Anthony, Lombard, Patrick, Hookway, Edward S, Szommer, Tamas, Johansson, Catrine, Brennan, Paul E, Pillay, Nischalan, Jenner, Richard G, Oppermann, Udo, Flanagan, Adrienne M

“…Expression of the transcription factor brachyury (TBXT) is normally restricted to the embryo, and its silencing is epigenetically regulated. TBXT promotes…”
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Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells by Tumber, Anthony, Nuzzi, Andrea, Hookway, Edward S, Hatch, Stephanie B, Velupillai, Srikannathasan, Johansson, Catrine, Kawamura, Akane, Savitsky, Pavel, Yapp, Clarence, Szykowska, Aleksandra, Wu, Na, Bountra, Chas, Strain-Damerell, Claire, Burgess-Brown, Nicola A, Ruda, Gian Filippo, Fedorov, Oleg, Munro, Shonagh, England, Katherine S, Nowak, Radoslaw P, Schofield, Christopher J, La Thangue, Nicholas B, Pawlyn, Charlotte, Davies, Faith, Morgan, Gareth, Athanasou, Nick, Müller, Susanne, Oppermann, Udo, Brennan, Paul E

“…Methylation of lysine residues on histone tail is a dynamic epigenetic modification that plays a key role in chromatin structure and gene regulation. Members…”
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Sclerostin expression in bone tumours and tumour-like lesions by Inagaki, Yusuke, Hookway, Edward S, Kashima, Takeshi G, Munemoto, Mitsuru, Tanaka, Yasuhito, Hassan, Andrew Bassim, Oppermann, Udo, Athanasou, Nick A

“…Aims To assess the immunophenotypic and mRNA expression of sclerostin in human skeletal tissues and in a wide range of benign and malignant bone tumours and…”
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Synovial chondromatosis and soft tissue chondroma: extra-osseous cartilaginous tumours defined by FN1 gene rearrangement by Amary, Fernanda, Perez-Casanova, Luis, Ye, Hongtao, Cottone, Lucia, Strobl, Anna, Cool, Paul, Miranda, Elena, Berisha, Fitim, Aston, William, Rocha, Maia, O’Donnell, Paul, Pillay, Nischalan, Tirabosco, Roberto, Baumhoer, Daniel, Hookway, Edward S, Flanagan, Adrienne M

“…A fusion between fibronectin 1 ( FN1 ) and activin receptor 2A ( ACVR2A ) has been reported previously in isolated cases of the synovial chondromatosis. To…”
Get full text