Search Results - "Hooker, Jonathan"

Liver fat imaging-a clinical overview of ultrasound, CT, and MR imaging by Zhang, Yingzhen N, Fowler, Kathryn J, Hamilton, Gavin, Cui, Jennifer Y, Sy, Ethan Z, Balanay, Michelle, Hooker, Jonathan C, Szeverenyi, Nikolaus, Sirlin, Claude B

“…Hepatic steatosis is a frequently encountered imaging finding that may indicate chronic liver disease, the most common of which is non-alcoholic fatty liver…”
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2017 Version of LI-RADS for CT and MR Imaging: An Update by Elsayes, Khaled M, Hooker, Jonathan C, Agrons, Michelle M, Kielar, Ania Z, Tang, An, Fowler, Kathryn J, Chernyak, Victoria, Bashir, Mustafa R, Kono, Yuko, Do, Richard K, Mitchell, Donald G, Kamaya, Aya, Hecht, Elizabeth M, Sirlin, Claude B

“…The Liver Imaging Reporting and Data System (LI-RADS) is a reporting system created for the standardized interpretation of liver imaging findings in patients…”
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Sitagliptin vs. placebo for non-alcoholic fatty liver disease: A randomized controlled trial by Cui, Jeffrey, Philo, Len, Nguyen, Phirum, Hofflich, Heather, Hernandez, Carolyn, Bettencourt, Ricki, Richards, Lisa, Salotti, Joanie, Bhatt, Archana, Hooker, Jonathan, Haufe, William, Hooker, Catherine, Brenner, David A, Sirlin, Claude B, Loomba, Rohit

“…Graphical abstract…”
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Accuracy of MR imaging-estimated proton density fat fraction for classification of dichotomized histologic steatosis grades in nonalcoholic fatty liver disease by Tang, An, Desai, Ajinkya, Hamilton, Gavin, Wolfson, Tanya, Gamst, Anthony, Lam, Jessica, Clark, Lisa, Hooker, Jonathan, Chavez, Tanya, Ang, Brandon D, Middleton, Michael S, Peterson, Michael, Loomba, Rohit, Sirlin, Claude B

“…To evaluate the diagnostic performance of previously proposed high-specificity magnetic resonance (MR) imaging-estimated proton density fat fraction (PDFF)…”
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LI-RADS Version 2018 Ancillary Features at MRI by Cerny, Milena, Chernyak, Victoria, Olivié, Damien, Billiard, Jean-Sébastien, Murphy-Lavallée, Jessica, Kielar, Ania Z, Elsayes, Khaled M, Bourque, Laurence, Hooker, Jonathan C, Sirlin, Claude B, Tang, An

“…The Liver Imaging Reporting and Data System (LI-RADS) standardizes performance of liver imaging in patients at risk for hepatocellular carcinoma (HCC) as well…”
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Ezetimibe for the treatment of nonalcoholic steatohepatitis: Assessment by novel magnetic resonance imaging and magnetic resonance elastography in a randomized trial (MOZART trial) by Loomba, Rohit, Sirlin, Claude B., Ang, Brandon, Bettencourt, Ricki, Jain, Rashmi, Salotti, Joanie, Soaft, Linda, Hooker, Jonathan, Kono, Yuko, Bhatt, Archana, Hernandez, Laura, Nguyen, Phirum, Noureddin, Mazen, Haufe, William, Hooker, Catherine, Yin, Meng, Ehman, Richard, Lin, Grace Y., Valasek, Mark A., Brenner, David A., Richards, Lisa

“…Ezetimibe inhibits intestinal cholesterol absorption and lowers low‐density lipoprotein cholesterol. Uncontrolled studies have suggested that it reduces liver…”
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Magnetic resonance imaging and liver histology as biomarkers of hepatic steatosis in children with nonalcoholic fatty liver disease by Schwimmer, Jeffrey B., Middleton, Michael S., Behling, Cynthia, Newton, Kimberly P., Awai, Hannah I., Paiz, Melissa N., Lam, Jessica, Hooker, Jonathan C., Hamilton, Gavin, Fontanesi, John, Sirlin, Claude B.

“…Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in children. In order to advance the field of NAFLD, noninvasive imaging…”
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Novel 3D Magnetic Resonance Elastography for the Noninvasive Diagnosis of Advanced Fibrosis in NAFLD: A Prospective Study by Loomba, Rohit, Cui, Jeffrey, Wolfson, Tanya, Haufe, William, Hooker, Jonathan, Szeverenyi, Nikolaus, Ang, Brandon, Bhatt, Archana, Wang, Kang, Aryafar, Hamed, Behling, Cindy, Valasek, Mark A, Lin, Grace Y, Gamst, Anthony, Brenner, David A, Yin, Meng, Glaser, Kevin J, Ehman, Richard L, Sirlin, Claude B

“…Recent studies show two-dimensional (2D)-magnetic resonance elastography (MRE) is accurate in diagnosing advanced fibrosis (stages 3 and 4) in nonalcoholic…”
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How bariatric surgery affects liver volume and fat density in NAFLD patients by Luo, Ran B., Suzuki, Toshiaki, Hooker, Jonathan C., Covarrubias, Yesenia, Schlein, Alexandra, Liu, Shanglei, Schwimmer, Jeffrey B., Reeder, Scott B., Funk, Luke M., Greenberg, Jacob A., Campos, Guilherme M., Sandler, Bryan J., Horgan, Santiago, Sirlin, Claude B., Jacobsen, Garth R.

“…Introduction Nonalcoholic fatty liver disease (NAFLD) is an epidemic in the obese population. Bariatric surgery is known to reverse multiple metabolic…”
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MR elastography in nonalcoholic fatty liver disease: inter-center and inter-analysis-method measurement reproducibility and accuracy at 3T by Tang, An, Dzyubak, Bogdan, Yin, Meng, Schlein, Alexandra, Henderson, Walter C., Hooker, Jonathan C., Delgado, Timoteo I., Middleton, Michael S., Zheng, Lin, Wolfson, Tanya, Gamst, Anthony, Loomba, Rohit, Ehman, Richard L., Sirlin, Claude B.

“…Objectives To assess reproducibility and fibrosis classification accuracy of magnetic resonance elastography (MRE)–determined liver stiffness measured manually…”
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Magnetic resonance elastography measured shear stiffness as a biomarker of fibrosis in pediatric nonalcoholic fatty liver disease by Schwimmer, Jeffrey B., Behling, Cynthia, Angeles, Jorge Eduardo, Paiz, Melissa, Durelle, Janis, Africa, Jonathan, Newton, Kimberly P., Brunt, Elizabeth M., Lavine, Joel E., Abrams, Stephanie H., Masand, Prakash, Krishnamurthy, Rajesh, Wong, Kelvin, Ehman, Richard L., Yin, Meng, Glaser, Kevin J., Dzyubak, Bogdan, Wolfson, Tanya, Gamst, Anthony C., Hooker, Jonathan, Haufe, William, Schlein, Alexandra, Hamilton, Gavin, Middleton, Michael S., Sirlin, Claude B.

“…Magnetic resonance elastography (MRE) is a promising technique for noninvasive assessment of fibrosis, a major determinant of outcome in nonalcoholic fatty…”
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Normal range for MR elastography measured liver stiffness in children without liver disease by Sawh, Mary Catherine, Newton, Kimberly P., Goyal, Nidhi P., Angeles, Jorge Eduardo, Harlow, Kathryn, Bross, Craig, Schlein, Alexandra N., Hooker, Jonathan C., Sy, Ethan Z., Glaser, Kevin J., Yin, Meng, Ehman, Richard L., Sirlin, Claude B., Schwimmer, Jeffrey B.

“…Background Magnetic resonance elastography (MRE) can determine the presence and stage of liver fibrosis. Data on normative MRE values, while reported in…”
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Association of noninvasive quantitative decline in liver fat content on MRI with histologic response in nonalcoholic steatohepatitis by Patel, Janki, Bettencourt, Ricki, Cui, Jeffrey, Salotti, Joanie, Hooker, Jonathan, Bhatt, Archana, Hernandez, Carolyn, Nguyen, Phirum, Aryafar, Hamed, Valasek, Mark, Haufe, William, Hooker, Catherine, Richards, Lisa, Sirlin, Claude B., Loomba, Rohit

“…Background: Magnetic resonance imaging-estimated proton-density-fat-fraction (MRI-PDFF) has been shown to be a noninvasive, accurate and reproducible…”
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Optimization of region‐of‐interest sampling strategies for hepatic MRI proton density fat fraction quantification by Hong, Cheng William, Wolfson, Tanya, Sy, Ethan Z., Schlein, Alexandra N., Hooker, Jonathan C., Fazeli Dehkordy, Soudabeh, Hamilton, Gavin, Reeder, Scott B., Loomba, Rohit, Sirlin, Claude B.

“…BACKGROUND Clinical trials utilizing proton density fat fraction (PDFF) as an imaging biomarker for hepatic steatosis have used a laborious region‐of‐interest…”
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Magnetic resonance elastography biomarkers for detection of histologic alterations in nonalcoholic fatty liver disease in the absence of fibrosis by Qu, Yali, Middleton, Michael S., Loomba, Rohit, Glaser, Kevin J., Chen, Jun, Hooker, Jonathan C., Wolfson, Tanya, Covarrubias, Yesenia, Valasek, Mark A., Fowler, Kathryn J., Zhang, Yingzhen N., Sy, Ethan, Gamst, Anthony C., Wang, Kang, Mamidipalli, Adrija, Schwimmer, Jeffrey B., Song, Bin, Reeder, Scott B., Yin, Meng, Ehman, Richard L., Sirlin, Claude B.

“…Objectives To investigate associations between histology and hepatic mechanical properties measured using multiparametric magnetic resonance elastography (MRE)…”
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Shared genetic effects between hepatic steatosis and fibrosis: A prospective twin study by Cui, Jeffrey, Chen, Chi‐Hua, Lo, Min‐Tzu, Schork, Nicholas, Bettencourt, Ricki, Gonzalez, Monica P., Bhatt, Archana, Hooker, Jonathan, Shaffer, Katherine, Nelson, Karen E., Long, Michelle T., Brenner, David A., Sirlin, Claude B., Loomba, Rohit, for the Genetics of NAFLD in Twins Consortium

“…Nonalcoholic fatty liver disease is associated with metabolic risk factors including hypertension and dyslipidemia and may progress to liver fibrosis. Studies…”
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Longitudinal evolution of CT and MRI LI-RADS v2014 category 1, 2, 3, and 4 observations by Hong, Cheng William, Park, Charlie C., Mamidipalli, Adrija, Hooker, Jonathan C., Fazeli Dehkordy, Soudabeh, Igarashi, Saya, Alhumayed, Mohanad, Kono, Yuko, Loomba, Rohit, Wolfson, Tanya, Gamst, Anthony, Murphy, Paul, Sirlin, Claude B.

“…Objectives This study assesses the risk of progression of Liver Imaging Reporting and Data System (LI-RADS) categories, and the effects of inter-exam changes…”
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MRI proton density fat fraction is robust across the biologically plausible range of triglyceride spectra in adults with nonalcoholic steatohepatitis by Hong, Cheng William, Mamidipalli, Adrija, Hooker, Jonathan C., Hamilton, Gavin, Wolfson, Tanya, Chen, Dennis H., Fazeli Dehkordy, Soudabeh, Middleton, Michael S., Reeder, Scott B., Loomba, Rohit, Sirlin, Claude B.

“…Background Proton density fat fraction (PDFF) estimation requires spectral modeling of the hepatic triglyceride (TG) signal. Deviations in the TG spectrum may…”
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Hepatic steatosis and reduction in steatosis following bariatric weight loss surgery differs between segments and lobes by Fazeli Dehkordy, Soudabeh, Fowler, Kathryn J., Mamidipalli, Adrija, Wolfson, Tanya, Hong, Cheng William, Covarrubias, Yesenia, Hooker, Jonathan C., Sy, Ethan Z., Schlein, Alexandra N., Cui, Jennifer Y., Gamst, Anthony C., Hamilton, Gavin, Reeder, Scott B., Sirlin, Claude B.

“…Objectives The purpose of this study was to (1) evaluate proton density fat fraction (PDFF) distribution across liver segments at baseline and (2) compare…”
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Weight Loss Decreases Magnetic Resonance Elastography Estimated Liver Stiffness in Nonalcoholic Fatty Liver Disease by Patel, Niraj S, Hooker, Jonathan, Gonzalez, Monica, Bhatt, Archana, Nguyen, Phirum, Ramirez, Kimberly, Richards, Lisa, Rizo, Emily, Hernandez, Carolyn, Kisseleva, Tatiana, Schnabl, Bernd, Brenner, David, Sirlin, Claude B, Loomba, Rohit

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