Search Results - "Hook, M"
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An HSV-2 nucleoside-modified mRNA genital herpes vaccine containing glycoproteins gC, gD, and gE protects mice against HSV-1 genital lesions and latent infection
Published in PLoS pathogens (01-07-2020)“…HSV-1 causes 50% of first-time genital herpes infections in resource-rich countries and affects 190 million people worldwide. A prophylactic herpes vaccine is…”
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2
Just add sugar for carbohydrate induced self-assembly of curcumin
Published in Nature communications (04-02-2019)“…In nature, self-assembly processes based on amphiphilic molecules play an integral part in the design of structures of higher order such as cells. Among them,…”
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3
Fire-derived organic matter retains ammonia through covalent bond formation
Published in Nature communications (08-02-2019)“…Fire-derived organic matter, often referred to as pyrogenic organic matter (PyOM), is present in the Earth’s soil, sediment, atmosphere, and water. We…”
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Cytomegalovirus miRNAs Target Secretory Pathway Genes to Facilitate Formation of the Virion Assembly Compartment and Reduce Cytokine Secretion
Published in Cell host & microbe (12-03-2014)“…Herpesviruses, including human cytomegalovirus (HCMV), encode multiple microRNAs (miRNA) whose targets are just being uncovered. Moreover, miRNA function…”
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The Gemini–North Multi‐Object Spectrograph: Performance in Imaging, Long‐Slit, and Multi‐Object Spectroscopic Modes
Published in Publications of the Astronomical Society of the Pacific (01-05-2004)“…Results of the commissioning of the first Gemini Multi‐Object Spectrograph (GMOS) are described. GMOS and the Gemini–North telescope act as a complete system…”
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The host galaxies of Type Ia supernovae discovered by the Palomar Transient Factory
Published in Monthly notices of the Royal Astronomical Society (21-02-2014)“…We present spectroscopic observations of the host galaxies of 82 low-redshift Type Ia supernovae (SNe Ia) discovered by the Palomar Transient Factory. We…”
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MicroRNA dysregulation following spinal cord contusion: implications for neural plasticity and repair
Published in Neuroscience (14-07-2011)“…Abstract Spinal cord injury (SCI) is medically and socioeconomically debilitating. Currently, there is a paucity of effective therapies that promote…”
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Sexually transmitted infections: Prevalence and clinical outcomes among pregnant women in Western Sydney
Published in International journal of gynecology and obstetrics (01-07-2024)“…Objective We report the prevalence, characteristics and clinical outcomes of women with sexually transmitted infections (STIs) in pregnancy in the Western…”
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Exploring the spectral diversity of low-redshift Type Ia supernovae using the Palomar Transient Factory
Published in Monthly notices of the Royal Astronomical Society (11-11-2014)“…We present an investigation of the optical spectra of 264 low-redshift (z < 0.2) Type Ia supernovae (SNe Ia) discovered by the Palomar Transient Factory, an…”
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The dependence of Type Ia Supernovae luminosities on their host galaxies
Published in Monthly notices of the Royal Astronomical Society (01-08-2010)“…Precision cosmology with Type Ia supernovae (SNe Ia) makes use of the fact that SN Ia luminosities depend on their light-curve shapes and colours. Using…”
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SiFTO: An Empirical Method for Fitting SN Ia Light Curves
Published in The Astrophysical journal (01-07-2008)“…We present SiFTO, a new empirical method for modeling Type Ia supernova (SN Ia) light curves by manipulating a spectral template. We make use of high-redshift…”
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An HSV-2 Trivalent Vaccine Is Immunogenic in Rhesus Macaques and Highly Efficacious in Guinea Pigs
Published in PLoS pathogens (01-01-2017)“…A genital herpes vaccine is urgently needed to prevent pain and suffering, reduce the incidence of neonatal herpes, and decrease the risk of HIV acquisition…”
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Human Cytomegalovirus MicroRNAs miR-US5-1 and miR-UL112-3p Block Proinflammatory Cytokine Production in Response to NF-κB-Activating Factors through Direct Downregulation of IKKα and IKKβ
Published in mBio (07-03-2017)“…Emerging evidence indicates that human cytomegalovirus (HCMV) manipulates host cell signaling pathways using both proteins and noncoding RNAs. Several studies…”
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Encapsulated Rose Bengal Enhances the Photodynamic Treatment of Triple-Negative Breast Cancer Cells
Published in Molecules (Basel, Switzerland) (01-01-2024)“…Among breast cancer subtypes, triple-negative breast cancer stands out as the most aggressive, with patients facing a 40% mortality rate within the initial…”
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Constraining the radio jet proper motion of the high-redshift quasar J2134−0419 at z = 4.3
Published in Monthly notices of the Royal Astronomical Society (11-06-2018)“…Abstract To date, PMN J2134–0419 (at a redshift z = 4.33) is the second most distant quasar known with a milliarcsecond-scale morphology permitting direct…”
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The type Ia supernova SNLS-03D3bb from a super-Chandrasekhar-mass white dwarf star
Published in Nature (21-09-2006)“…The accelerating expansion of the Universe, and the need for dark energy, were inferred from observations of type Ia supernovae. There is a consensus that type…”
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Near-infrared observations of Type Ia supernovae: the best known standard candle for cosmology
Published in Monthly notices of the Royal Astronomical Society (11-09-2012)“…Abstract We present an analysis of the Hubble diagram for 12 normal Type Ia supernovae (SNe Ia) observed in the near-infrared (NIR) J and H bands. We select…”
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Vaccine-induced antibodies to herpes simplex virus glycoprotein D epitopes involved in virus entry and cell-to-cell spread correlate with protection against genital disease in guinea pigs
Published in PLoS pathogens (01-05-2018)“…Herpes simplex virus type 2 (HSV-2) glycoprotein D (gD2) subunit antigen is included in many preclinical candidate vaccines. The rationale for including gD2 is…”
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Evaluation of the effects of specific opioid receptor agonists in a rodent model of spinal cord injury
Published in Spinal cord (01-10-2016)“…Objective: The current study aimed to evaluate the contribution(s) of specific opioid receptor systems to the analgesic and detrimental effects of morphine,…”
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Survival from high-grade localised extremity osteosarcoma: combined results and prognostic factors from three European Osteosarcoma Intergroup randomised controlled trials
Published in Annals of oncology (01-06-2012)“…Neoadjuvant chemotherapy improves outcome in osteosarcoma. Determination of optimum regimens for survival, toxicity and prognostic factors requires randomised…”
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