Search Results - "Hook, Jaime"
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A role for TMEM63 in the lung
Published in The Journal of clinical investigation (01-03-2024)“…Surfactants are essential for breathing. Although major progress has been made in the past half century toward an understanding of surfactant secretion…”
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The pathogenesis of influenza in intact alveoli: virion endocytosis and its effects on the lung's air-blood barrier
Published in Frontiers in immunology (2024)“…Lung infection by influenza A virus (IAV) is a major cause of global mortality from lung injury, a disease defined by widespread dysfunction of the lung's…”
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Disruption of staphylococcal aggregation protects against lethal lung injury
Published in The Journal of clinical investigation (01-03-2018)“…Infection by Staphylococcus aureus strain USA300 causes tissue injury, multiorgan failure, and high mortality. However, the mechanisms by which the bacteria…”
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Alveolar Responses to Influenza Lung Infection Determined by Confocal Imaging of Live Lungs
Published in The FASEB journal (01-05-2022)“…One‐third of patients with severe lung infection by influenza A virus (IAV) develop secondary lung infection by inhaled S. aureus(SA), leading to mortality in…”
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Generation and persistence of human tissue-resident memory T cells in lung transplantation
Published in Science immunology (08-03-2019)“…Tissue-resident memory T cells (T ) maintain immunity in diverse sites as determined in mouse models, whereas their establishment and role in human tissues…”
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Rescue of alveolar wall liquid secretion blocks fatal lung injury due to influenza-staphylococcal coinfection
Published in The Journal of clinical investigation (01-10-2023)“…Secondary lung infection by inhaled Staphylococcus aureus (SA) is a common and lethal event for individuals infected with influenza A virus (IAV). How IAV…”
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A shift in lung macrophage composition is associated with COVID-19 severity and recovery
Published in Science translational medicine (14-09-2022)“…Although it has been more than 2 years since the start of the coronavirus disease 2019 (COVID-19) pandemic, COVID-19 continues to be a worldwide health crisis…”
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Geographic disparities in donor lung supply and lung transplant waitlist outcomes: A cohort study
Published in American journal of transplantation (01-06-2018)“…Despite the Final Rule mandate for equitable organ allocation in the United States, geographic disparities exist in donor lung allocation, with the majority of…”
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Selecting lung transplant candidates: where do current guidelines fall short?
Published in Expert review of respiratory medicine (01-02-2012)“…In 2010, 1770 lung transplant procedures were performed in the USA, yet 2469 new candidates were added to the waiting list the same year. The shortage of…”
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Low-Burden Strategies to Promote Smoking Cessation Treatment Among Patients With Serious Mental Illness
Published in Psychiatric services (Washington, D.C.) (01-08-2018)“…Patients with serious mental illness have high smoking prevalence and early mortality. Inadequate implementation of evidence-based smoking cessation treatment…”
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Socioeconomic barriers to lung transplantation: balancing access and equity
Published in American journal of respiratory and critical care medicine (15-11-2012)Get full text
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New Insights into the Alveolar Epithelium as a Driver of Acute Respiratory Distress Syndrome
Published in Biomolecules (Basel, Switzerland) (01-09-2022)“…The alveolar epithelium serves as a barrier between the body and the external environment. To maintain efficient gas exchange, the alveolar epithelium has…”
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Regulatory T Cells Promote Macrophage Efferocytosis during Inflammation Resolution
Published in Immunity (Cambridge, Mass.) (16-10-2018)“…Regulatory T (Treg) cell responses and apoptotic cell clearance (efferocytosis) represent critical arms of the inflammation resolution response. We sought to…”
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Molecular states during acute COVID-19 reveal distinct etiologies of long-term sequelae
Published in Nature medicine (2023)“…Post-acute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection are debilitating, clinically heterogeneous and of unknown…”
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Downregulation of exhausted cytotoxic T cells in gene expression networks of multisystem inflammatory syndrome in children
Published in Nature communications (11-08-2021)“…Multisystem inflammatory syndrome in children (MIS-C) presents with fever, inflammation and pathology of multiple organs in individuals under 21 years of age…”
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Low-Burden Strategies to Promote Smoking Cessation Treatment in Patients with Serious Mental Illness
Published in Psychiatric services (Washington, D.C.) (01-06-2018)“…Patients with serious mental illness have high smoking prevalence and early mortality. Inadequate implementation of evidence-based smoking cessation treatment…”
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Sampling the host response to SARS-CoV-2 in hospitals under siege
Published in Nature medicine (01-08-2020)Get full text
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A Potential Role for Regulatory T Cells in Apoptotic Cell Clearance by Macrophages in a Murine Model of Acute Lung Injury
Published in The FASEB journal (01-04-2015)“…Abstract only A key step in inflammation resolution is the clearance of apoptotic cells, or efferocytosis. Murine models of acute lung injury (ALI) have…”
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Author Correction: Sampling the host response to SARS-CoV-2 in hospitals under siege
Published in Nature medicine (01-03-2021)“…A Correction to this paper has been published: https://doi.org/10.1038/s41591-021-01247-3…”
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