Search Results - "Hooijberg, J.H"

Folates and antifolates in the treatment of cancer; role of folic acid supplementation on efficacy of folate and non-folate drugs by Peters, G.J., Hooijberg, J.H., Kaspers, G.J.L., Jansen, G.

“…Folates are essential nutrients for the cell for DNA synthesis. From a nutritional perspective, a high folate status may have a beneficial/protective effect…”
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Modulation by (iso)flavonoids of the ATPase activity of the multidrug resistance protein by Hooijberg, J.H, Broxterman, H.J, Heijn, M, Fles, D.L.A, Lankelma, J, Pinedo, H.M

“…The multidrug resistance protein (MRP) is an ATP-dependent transport protein for organic anions, as well as neutral or positively charged anticancer agents. In…”
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Dendritic cells require multidrug resistance protein 1 (ABCC1) transporter activity for differentation by Ven, R., van de, Jong, M.C.M., de, Reurs, A.W, Schoonderwoerd, A.J, Jansen, G, Hooijberg, J.H, Scheffer, G.L, Gruijl, T.D, Scheper, R.J

“…Dendritic cells (DC) express the ATP-binding cassette (ABC) transporters P-glycoprotein (ABCB1) and multidrug resistance protein 1 (MRP1; ABCC1). Functionally,…”
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The effect of glutathione on the ATPase activity of MRP1 in its natural membranes by Hooijberg, J.H, Pinedo, H.M, Vrasdonk, C, Priebe, W, Lankelma, J, Broxterman, H.J

“…The transport mechanism by which the multidrug resistance protein 1 (MRP1) effluxes cytotoxic agents out of cells is still not completely understood. However,…”
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Multidrug-Resistant Tumor Cells Remain Sensitive to a Recombinant Interleukin-4-Pseudomonas Exotoxin, Except When Overexpressing the Multidrug Resistance Protein MRP1 by DE JONG, Mariska C, SCHEFFER, George L, SCHEPER, Rik J, BROXTERMAN, Henk J, HOOIJBERG, Jan H, SLOOTSTRA, Jerry W, MELOEN, Rob H, KREITMAN, Robert J, HUSAIN, Syed R, JOSHI, Bharat H, PURI, Raj K

“…Tumor cells may become resistant to conventional anticancer drugs through the occurrence of transmembrane transporter proteins such as P-glycoprotein (ABCB1),…”
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