Search Results - "Hooi, Michelle Yu Sung"
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Racemisation and human cataract. d-Ser, d-Asp/Asn and d-Thr are higher in the lifelong proteins of cataract lenses than in age-matched normal lenses
Published in AGE (01-06-2011)“…Astract Several amino acids were found to undergo progressive age-dependent racemisation in the lifelong proteins of normal human lenses. The two most highly…”
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Racemization of two proteins over our lifespan: deamidation of asparagine 76 in γS crystallin is greater in cataract than in normal lenses across the age range
Published in Investigative ophthalmology & visual science (14-06-2012)“…Long-lived proteins are widespread in man, yet little is known about the processes that affect their function over time, or their role in age-related diseases…”
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Journal Article -
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Age‐dependent deamidation of glutamine residues in human γS crystallin: Deamidation and unstructured regions
Published in Protein science (01-07-2012)“…Human aging is associated with the deterioration of long‐lived proteins. Gradual cumulative modifications to the life‐long proteins of the lens may ultimately…”
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Journal Article -
4
Age-dependent deamidation of glutamine residues in human [gamma]S crystallin: Deamidation and unstructured regions
Published in Protein science (01-07-2012)“…Human aging is associated with the deterioration of long-lived proteins. Gradual cumulative modifications to the life-long proteins of the lens may ultimately…”
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Journal Article