Search Results - "Hoogi, Shiran"

A TIGIT-based chimeric co-stimulatory switch receptor improves T-cell anti-tumor function by Hoogi, Shiran, Eisenberg, Vasyl, Mayer, Shimrit, Shamul, Astar, Barliya, Tilda, Cohen, Cyrille J.

“…BackgroundTumors can employ different mechanisms to evade immune surveillance and function. Overexpression of co-inhibitory ligands that bind to checkpoint…”
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Targeting Multiple Tumors Using T-Cells Engineered to Express a Natural Cytotoxicity Receptor 2-Based Chimeric Receptor by Eisenberg, Vasyl, Shamalov, Katerina, Meir, Shimrit, Hoogi, Shiran, Sarkar, Rhitajit, Pinker, Shirel, Markel, Gal, Porgador, Angel, Cohen, Cyrille J

“…Recent developments in cancer treatment are demonstrating the increasing and powerful potential of immunotherapeutic strategies. In this regard, the adoptive…”
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Genetically engineering glycolysis in T cells increases their antitumor function by Toledano Zur, Raphaëlle, Atar, Orna, Barliya, Tilda, Hoogi, Shiran, Abramovich, Ifat, Gottlieb, Eyal, Ron-Harel, Noga, Cohen, Cyrille J

“…BackgroundT cells play a central role in the antitumor response. However, they often face numerous hurdles in the tumor microenvironment, including the…”
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T-cells “à la CAR-T(e)” – Genetically engineering T-cell response against cancer by Eisenberg, Vasyl, Hoogi, Shiran, Shamul, Astar, Barliya, Tilda, Cohen, Cyrille J.

“…The last decade will be remembered as the dawn of the immunotherapy era during which we have witnessed the approval by regulatory agencies of genetically…”
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Targeting Tumor-Associated Sialic Acids Using Chimeric Switch Receptors Based on Siglec-9 Enhances the Antitumor Efficacy of Engineered T Cells by Eisenberg, Vasyl, Hoogi, Shiran, Katzman, Erel, Ben Haim, Nimrod, Zur-Toledano, Raphaelle, Radman, Maria, Reboh, Yishai, Zadok, Oranit, Kamer, Iris, Bar, Jair, Sagi, Irit, Hendel, Ayal, Cohen, Cyrille J

“…Cancer exploits different mechanisms to escape T-cell immunosurveillance, including overexpression of checkpoint ligands, secretion of immunosuppressive…”
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