Search Results - "Hoogenboom, L."

Development and Application of a Liquid Chromatography–Tandem Mass Spectrometry Method for the Analysis of 20 Perfluoroalkyl Substances in Fruit and Vegetables at Sub-Parts-per-Trillion Levels by Kause, Ruben, van Leeuwen, Stefan, Krätschmer, Kerstin, van Dooren, Bob, Keppels, Rens, Makarem, Helgah, Hoogenboom, L. Ron A. P., de Pagter-de Witte, Leontien, Berendsen, Bjorn J. A.

“…In response to the European Food Safety Authority’s establishment of a tolerable weekly intake (TWI) for the sum of PFOA, PFNA, PFHxS, and PFOS, a method was…”
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Urine Testing for Designer Steroids by Liquid Chromatography with Androgen Bioassay Detection and Electrospray Quadrupole Time-of-Flight Mass Spectrometry Identification by Nielen, Michel W. F, Bovee, Toine F. H, van Engelen, Marcel C, Rutgers, Paula, Hamers, Astrid R. M, van Rhijn, J. (Hans) A, Hoogenboom, L. (Ron) A. P

“…New anabolic steroids show up occasionally in sports doping and in veterinary control. The discovery of these designer steroids is facilitated by findings of…”
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Current Insights into Monitoring, Bioaccumulation, and Potential Health Effects of Microplastics Present in the Food Chain by van Raamsdonk, Leonard W D, van der Zande, Meike, Koelmans, Albert A, Hoogenboom, Ron L A P, Peters, Ruud J B, Groot, Maria J, Peijnenburg, Ad A C M, Weesepoel, Yannick J A

“…Microplastics (MPs) are considered an emerging issue as environmental pollutants and a potential health threat. This review will focus on recently published…”
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First Report on the Occurrence of Tetrodotoxins in Bivalve Mollusks in The Netherlands by Gerssen, Arjen, Bovee, Toine H F, Klijnstra, Mirjam D, Poelman, Marnix, Portier, Liza, Hoogenboom, Ron L A P

“…Tetrodotoxin (TTX) is traditionally associated with seafood from tropical regions, but recently TTX was detected in bivalve mollusks in more temperate European…”
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Perfluoroalkyl substances (PFASs) decrease the expression of recombination-activating genes (RAG1 and RAG2) in human B lymphoma Namalwa cells by Janssen, Aafke W. F., Louisse, Jochem, Rijkers, Deborah, Pinckaers, Nicole E. T., Hoekstra, Sjoerdtje A., Hoogenboom, Ron L. A. P., Peijnenburg, Ad A. C. M., Beekmann, Karsten

“…Per- and polyfluoroalkyl substances (PFASs) are omnipresent and have been shown to induce a wide range of adverse effects, including hepatotoxicity,…”
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Exposure assessment of cattle via roughages to plants producing compounds of concern by van Raamsdonk, L.W.D., Ozinga, W.A., Hoogenboom, L.A.P., Mulder, P.P.J., Mol, J.G.J., Groot, M.J., van der Fels-Klerx, H.J., de Nijs, M.

“…•Animals are unintentionally exposed to a wide range of wild plants.•Over twenty percent of the plants consumed by cattle contain compounds of…”
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Levels of polychlorinated dibenzo-p-dioxins, dibenzofurans (PCDD/Fs) and dioxin-like PCBs in free range eggs from Vietnam, including potential health risks by Hoang, Thu T., Traag, Wim A., Murk, AlberTinka J., Hoogenboom, Ron L.A.P.

“…•Eggs from areas contaminated by Agent Orange showed very high dioxin levels.•TCDD was the most important congener in these eggs.•Consumption of these eggs…”
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Tailored Microarray Platform for the Detection of Marine Toxins by Bovee, T. F. H, Hendriksen, P. J. M, Portier, L, Wang, S, Elliott, C. T, van Egmond, H. P, Nielen, M. W. F, Peijnenburg, A. A. C. M, Hoogenboom, L. A. P

“…Currently, there are no fast in vitro broad spectrum screening bioassays for the detection of marine toxins. The aim of this study was to develop such an…”
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A Strategy to Replace the Mouse Bioassay for Detecting and Identifying Lipophilic Marine Biotoxins by Combining the Neuro-2a Bioassay and LC-MS/MS Analysis by Bodero, Marcia, Gerssen, Arjen, Portier, Liza, Klijnstra, Mirjam D, Hoogenboom, Ron L A P, Guzmán, Leonardo, Hendriksen, Peter J M, Bovee, Toine F H

“…Marine biotoxins in fish and shellfish can cause several symptoms in consumers, such as diarrhea, amnesia, or even death by paralysis. Monitoring programs are…”
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A congener-specific modelling approach for the transfer of polychlorinated dibenzo-p-dioxins and dibenzofurans and dioxin-like polychlorinated biphenyls from feed to eggs of laying hens by Notenboom, Sylvia, Punt, Ans, Hoogenveen, Rudolf, Zeilmaker, Marco J., Hoogenboom, Ron L. A. P., Bokkers, Bas G. H.

“…Calibration of a kinetic model for the transfer of PCDD/Fs and dl-PCBs from feed to the hen's body and eggs was thus far restricted to the total TEQ…”
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Residues of dioxins (PCDD/Fs) and PCBs in eggs, fat and livers of laying hens following consumption of contaminated feed by Traag, W.A., Kan, C.A., van der Weg, G., Onstenk, C., Hoogenboom, L.A.P.

“…Laying hens were fed with feed from the Belgian dioxin incident diluted ten-fold with non-contaminated feed, resulting in concentrations of 61 ng TEQ kg −1…”
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Sildenafil and analogous phosphodiesterase type 5 (PDE-5) inhibitors in herbal food supplements sampled on the Dutch market by Reeuwijk, N.M, Venhuis, B.J, de Kaste, D, Hoogenboom, L.A.P, Rietjens, I.M.C.M, Martena, M.J

“…Herbal food supplements, claiming to enhance sexual potency, may contain deliberately added active pharmacological ingredients (APIs) that can be used for the…”
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Screening for Modulatory Effects on Steroidogenesis Using the Human H295R Adrenocortical Cell Line: A Metabolomics Approach by Rijk, Jeroen C. W, Peijnenburg, Ad A. C. M, Blokland, Marco H, Lommen, Arjen, Hoogenboom, Ron L. A. P, Bovee, Toine F. H

“…The recently OECD validated H295R steroidogenesis assay provides an in vitro alternative to evaluate the potential interference of exogenous compounds with…”
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Carry-over of pyrrolizidine alkaloids from feed to milk in dairy cows by Hoogenboom, L.A.P, Mulder, P.P.J, Zeilmaker, M.J, van den Top, H.J, Remmelink, G.J, Brandon, E.F.A, Klijnstra, M, Meijer, G.A.L, Schothorst, R, Van Egmond, H.P

“…Pyrrolizidine alkaloids are toxins present in many plants belonging to the families of Asteraceae, Boraginaceae and Fabaceae. Particularly notorious are…”
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A novel source for dioxins present in recycled fat from gelatin production by Hoogenboom, L.A.P., Van Eijkeren, J.C.H., Zeilmaker, M.J., Mengelers, M.J.B., Herbes, R., Immerzeel, J., Traag, W.A.

“…Within a survey on dioxins in animal fat used as feed ingredient, a sample originating from pigs offal was shown to contain 50 ng Toxic Equivalents (TEQ)…”
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Effect of Flock Size on Dioxin Levels in Eggs from Chickens Kept Outside by Kijlstra, A, Traag, W.A, Hoogenboom, L.A.P

“…To decrease dioxin uptake by the general population the European Union (EU) has set limits to the dioxin content of many foodstuffs including eggs. Eggs from…”
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Transfer of pyrrolizidine alkaloids from various herbs to eggs and meat in laying hens by Mulder, Patrick P. J., de Witte, Susannah L., Stoopen, Geert M., van der Meulen, Jan, van Wikselaar, Piet G., Gruys, Erik, Groot, Maria J., Hoogenboom, Ron L. A. P.

“…To investigate the potential transfer of pyrrolizidine alkaloids (PAs), laying hens were fed for 14 days with diets containing 0.5% of dried common ragwort,…”
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Quantitative in vitro-to-in vivo extrapolation (QIVIVE) of estrogenic and anti-androgenic potencies of BPA and BADGE analogues by Punt, Ans, Aartse, Aafke, Bovee, Toine F. H., Gerssen, Arjen, van Leeuwen, Stefan P. J., Hoogenboom, Ron L. A. P., Peijnenburg, Ad A. C. M.

“…The goal of the present study was to obtain an in vivo relevant prioritization method for the endocrine potencies of different polycarbonate monomers, by…”
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Identification of phosphodiesterase type-5 (PDE-5) inhibitors in herbal supplements using a tiered approach and associated consumer risk by Akuamoa, Felicia, Bovee, Toine F. H., van Dam, Ruud, Maro, Lilian, Wesseling, Sebastiaan, Vervoort, Jacques, Rietjens, Ivonne M. C. M., Hoogenboom, Ron L. A. P.

“…The use of herbal supplements for improved sexual performance is a common practice amongst the youth and some senior citizens in Ghana. These products are…”
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Polychlorinated dibenzo-p-dioxins, dibenzofurans and biphenyls in fish from the Netherlands: concentrations, profiles and comparison with DR CALUX® bioassay results by van Leeuwen, S. P. J, Leonards, P. E. G, Traag, W. A, Hoogenboom, L. A. P, de Boer, J

“…Fish from Dutch markets were analysed for concentrations of polychlorinated dibenzo-p-dioxins/dibenzofurans (PCDD/Fs) and dioxin-like polychlorinated biphenyls…”
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