Search Results - "Hoogeland, Bas S.J."

Role of XIAP in inhibiting cisplatin-induced caspase activation in non-small cell lung cancer cells: A small molecule Smac mimic sensitizes for chemotherapy-induced apoptosis by enhancing caspase-3 activation by Checinska, Agnieszka, Hoogeland, Bas S.J., Rodriguez, Jose A., Giaccone, Giuseppe, Kruyt, Frank A.E.

“…X-linked IAP (XIAP) suppresses apoptosis by binding to initiator caspase-9 and effector caspases-3 and -7. Smac/DIABLO that is released from mitochondria…”
Get full text

TUCAN/CARDINAL/CARD8 and apoptosis resistance in non-small cell lung cancer cells by Checinska, Agnieszka, Giaccone, Giuseppe, Hoogeland, Bas S J, Ferreira, Carlos G, Rodriguez, Jose A, Kruyt, Frank A E

“…Activation of caspase-9 in response to treatment with cytotoxic drugs is inhibited in NSCLC cells, which may contribute to the clinical resistance to…”
Get full text