Search Results - "Hoogd, Sjoerd"
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Postoperative breakthrough pain in paediatric cardiac surgery not reduced by increased morphine concentrations
Published in Pediatric research (01-12-2021)“…Background Morphine is commonly used for postoperative analgesia in children. Here we studied the pharmacodynamics of morphine in children after cardiac…”
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2
Randomized Controlled Trial on the Influence of Intraoperative Remifentanil versus Fentanyl on Acute and Chronic Pain after Cardiac Surgery
Published in Pain practice (01-04-2018)“…Background Remifentanil has been associated with increased acute and potentially chronic postoperative pain. The objective of this prospective randomized…”
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3
Obesity and drug pharmacology: a review of the influence of obesity on pharmacokinetic and pharmacodynamic parameters
Published in Expert opinion on drug metabolism & toxicology (04-03-2018)“…The rising prevalence of obesity confronts clinicians with dosing problems in the (extreme) overweight population. Obesity has a great impact on key organs…”
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OPRM1 and COMT polymorphisms: implications on postoperative acute, chronic and experimental pain after cardiac surgery
Published in Pharmacogenomics (01-02-2020)“…Investigate the potential role of (mu-opioid receptor) and (catechol-O-methyltransferase enzyme) polymorphisms in postoperative acute, chronic and experimental…”
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Severe pancytopenia and aspergillosis caused by thioguanine in a thiopurine S-methyltransferase deficient patient: a case report
Published in European journal of gastroenterology & hepatology (01-12-2019)“…Azathioprine and mercaptopurine are widely used in the treatment of inflammatory bowel disease. However, its use is limited by adverse drug event related to…”
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Influence of Morbid Obesity on the Pharmacokinetics of Morphine, Morphine-3-Glucuronide, and Morphine-6-Glucuronide
Published in Clinical pharmacokinetics (01-12-2017)“…Introduction Obesity is associated with many pathophysiological changes that may result in altered drug metabolism. The aim of this study is to investigate the…”
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Is Intraoperative Remifentanil Associated With Acute or Chronic Postoperative Pain After Prolonged Surgery? An Update of the Literature
Published in The Clinical journal of pain (01-08-2016)“…OBJECTIVE:Remifentanil is an ultra-short-acting opioid that is used commonly during both short-term and prolonged surgery. This review investigated…”
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Short- and long-term impact of remifentanil on thermal detection and pain thresholds after cardiac surgery: A randomised controlled trial
Published in European journal of anaesthesiology (01-01-2019)“…BACKGROUNDThe clinical relevance of the suggested hyperalgesic effects of remifentanil is still unclear, especially in the long term. OBJECTIVEThe current…”
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Differences in body mass index z-scores and weight status in a Dutch pediatric psychiatric population with and without use of second-generation antipsychotics
Published in Journal of child and adolescent psychopharmacology (01-04-2012)“…Weight gain and metabolic adverse effects of second-generation antipsychotics (SGAs) have become a major concern, particularly in youth. However, the specific…”
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Remifentanil versus fentanyl during cardiac surgery on the incidence of chronic thoracic pain (REFLECT): study protocol for a randomized controlled trial
Published in Trials (27-11-2014)“…Chronic thoracic pain after cardiac surgery is prevalent (11 to 56%) and may affect patients' physical and mental health status. Despite its favorable…”
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