Search Results - "Hooff, Gero P"

Regulation of the brain isoprenoids farnesyl- and geranylgeranylpyrophosphate is altered in male Alzheimer patients by Eckert, Gunter P, Hooff, Gero P, Strandjord, Dana M, Igbavboa, Urule, Volmer, Dietrich A, Müller, Walter E, Wood, W. Gibson

“…Abstract Post-translational modification of small GTPases by farnesyl- (FPP) and geranylgeranylpyrophosphate (GGPP) has generated much attention due to their…”
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Analytical investigations of toxic p-phenylenediamine (PPD) levels in clinical urine samples with special focus on MALDI-MS/MS by Hooff, Gero P, van Huizen, Nick A, Meesters, Roland J W, Zijlstra, Eduard E, Abdelraheem, Mohamed, Abdelraheem, Waleed, Hamdouk, Mohamed, Lindemans, Jan, Luider, Theo M

“…Para-phenylenediamine (PPD) is a common chromophoric ingredient in oxidative hair-dyes. In some African countries like Sudan, Egypt and Morocco but also in…”
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Modulation of Cholesterol, Farnesylpyrophosphate, and Geranylgeranylpyrophosphate in Neuroblastoma SH-SY5Y-APP695 Cells: Impact on Amyloid Beta-Protein Production by Hooff, Gero P, Peters, Imke, Wood, W. Gibson, Müller, Walter E, Eckert, Gunter P

“…There is keen interest in the role of the isoprenoids farnesylpyrophosphate (FPP) and geranylgeranylpyrophosphate (GGPP) in protein prenylation and cell…”
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State-of-the-art dried blood spot analysis: an overview of recent advances and future trends by Meesters, Roland Jw, Hooff, Gero P

“…Dried blood spots have become a popular method in a variety of micro blood-sampling techniques in the life sciences sector, consequently competing with the…”
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Characterization of β-Lactamase Enzyme Activity in Bacterial Lysates using MALDI-Mass Spectrometry by Hooff, Gero P, van Kampen, Jeroen J. A, Meesters, Roland J. W, van Belkum, Alex, Goessens, Wil H. F, Luider, Theo M

“…Plasmid-encoded β-lactamases are a major reason for antibiotic resistance in Gram negative bacteria. These enzymes hydrolyze the β-lactam ring structure of…”
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Dried matrix on paper disks: the next generation DBS microsampling technique for managing the hematocrit effect in DBS analysis by Meesters, Roland Jw, Zhang, Jamie, van Huizen, Nick A, Hooff, Gero P, Gruters, Rob A, Luider, Theo M

“…The hematocrit effect is a hurdle for successful introduction of the dried blood spot (DBS) in a regulated environment. Recently, attempts were taken to…”
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Brain Isoprenoids Farnesyl Pyrophosphate and Geranylgeranyl Pyrophosphate are Increased in Aged Mice by Hooff, Gero P., Wood, W. Gibson, Kim, Ji-Hyun, Igbavboa, Urule, Ong, Wei-Yi, Muller, Walter E., Eckert, Gunter P.

“…The mevalonate/isoprenoids/cholesterol pathway has a fundamental role in the brain. Increasing age could be associated with specific changes in mevalonate…”
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Isoprenoids, small GTPases and Alzheimer's disease by Hooff, Gero P., Wood, W. Gibson, Müller, Walter E., Eckert, Gunter P.

“…The mevalonate pathway is a crucial metabolic pathway for most eukaryotic cells. Cholesterol is a highly recognized product of this pathway but growing…”
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rapid and sensitive assay for determining human brain levels of farnesyl-(FPP) and geranylgeranylpyrophosphate (GGPP) and transferase activities using UHPLC-MS/MS by Hooff, Gero P, Patel, Nina, Wood, W. Gibson, Müller, Walter E, Eckert, Gunter P, Volmer, Dietrich A

“…The isoprenoids farnesyl-(FPP) and geranylgeranylpyrophosphate (FPP and GGPP) are two major lipid intermediates in the mevalonate pathway. They participate in…”
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Dried blood spot UHPLC-MS/MS analysis of oseltamivir and oseltamivircarboxylate—a validated assay for the clinic by Hooff, Gero P., Meesters, Roland J. W., van Kampen, Jeroen J. A., van Huizen, Nick A., Koch, Birgit, Al Hadithy, Asmar F. Y., van Gelder, Teun, Osterhaus, Albert D. M. E., Gruters, Rob A., Luider, Theo M.

“…The neuraminidase inhibitor oseltamivir (Tamiflu®) is currently the first-line therapy for patients with influenza virus infection. Common analysis of the…”
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Isoprenoid quantitation in human brain tissue: a validated HPLC-fluorescence detection method for endogenous farnesyl- (FPP) and geranylgeranylpyrophosphate (GGPP) by Hooff, Gero P, Volmer, Dietrich A, Wood, W. Gibson, Müller, Walter E, Eckert, Gunter P

“…Farnesyl- and geranylgeranylpyrophosphate (FPP and GGPP) are isoprenoid intermediates in the mevalonate pathway. They play a crucial role in cell survival,…”
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Incurred sample reanalysis comparison of dried blood spots and plasma samples on the measurement of lopinavir in clinical samples by Meesters, Roland J W, Hooff, Gero P, Gruters, Rob, van Kampen, Jeroen J A, Luider, Theo M

“…Undoubtedly, incurred sample reanalysis (ISR) will become an integral part of regulated bioanalysis of dried blood spot (DBS) samples. In this article, we…”
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Brain Isoprenoids Farnesyl Pyrophosphate and Geranylgeranyl Pyrophosphate are Increased in Aged Mice by Hooff, Gero P., Wood, W. Gibson, Kim, Ji-Hyun, Igbavboa, Urule, Ong, Wei-Yi, Muller, Walter E., Eckert, Gunter P.

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Analytical Investigations of Toxic p-Phenylenediamine by Hooff, Gero P, van Huizen, Nick A, Meesters, Roland J. W, Zijlstra, Eduard E, Abdelraheem, Mohamed, Abdelraheem, Waleed, Hamdouk, Mohamed, Lindemans, Jan, Luider, Theo M

“…Para-phenylenediamine (PPD) is a common chromophoric ingredient in oxidative hair-dyes. In some African countries like Sudan, Egypt and Morocco but also in…”
Get full text

A rapid and sensitive assay for determining human brain levels of farnesyl- and transferase activities using UHPLC-MS/MS by Hooff, Gero P, Patel, Nina, Wood, W. Gibson, Muller, Walter E, Eckert, Gunter P, Volmer, Dietrich A

“…The isoprenoids farnesyl-(FPP) and geranylgeranyl-pyrophosphate (FPP and GGPP) are two major lipid inter-mediates in the mevalonate pathway. They participate…”
Get full text