Search Results - "Hooda, Yogesh"
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A Slam-dependent hemophore contributes to heme acquisition in the bacterial pathogen Acinetobacter baumannii
Published in Nature communications (01-11-2021)“…Nutrient acquisition systems are often crucial for pathogen growth and survival during infection, and represent attractive therapeutic targets. Here, we study…”
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Molecular mechanism of azithromycin resistance among typhoidal Salmonella strains in Bangladesh identified through passive pediatric surveillance
Published in PLoS neglected tropical diseases (15-11-2019)“…With the rise in fluoroquinolone-resistant Salmonella Typhi and the recent emergence of ceftriaxone resistance, azithromycin is one of the last oral drugs…”
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3
Reconstitution of surface lipoprotein translocation through the Slam translocon
Published in eLife (27-04-2022)“…Surface lipoproteins (SLPs) are peripherally attached to the outer leaflet of the outer membrane in many Gram-negative bacteria, playing significant roles in…”
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Tracking the Emergence of Azithromycin Resistance in Multiple Genotypes of Typhoidal Salmonella
Published in mBio (16-02-2021)“…The rising prevalence of antimicrobial resistance in serovars Typhi and Paratyphi A, causative agents of typhoid and paratyphoid, have led to fears of…”
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Paratype: a genotyping tool for Salmonella Paratyphi A reveals its global genomic diversity
Published in Nature communications (23-12-2022)“…Salmonella Paratyphi A, the primary etiology of paratyphoid, is estimated to cause 3.4 million infections annually, worldwide. With rising antimicrobial…”
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Actinobacillus utilizes a binding protein–dependent ABC transporter to acquire the active form of vitamin B6
Published in The Journal of biological chemistry (01-09-2021)“…Bacteria require high-efficiency uptake systems to survive and proliferate in nutrient-limiting environments, such as those found in host organisms. ABC…”
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Old tools, new applications: Use of environmental bacteriophages for typhoid surveillance and evaluating vaccine impact
Published in PLoS neglected tropical diseases (01-02-2024)“…Typhoid-conjugate vaccines (TCVs) provide an opportunity to reduce the burden of typhoid fever, caused by Salmonella Typhi, in endemic areas. As policymakers…”
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Large‐scale survey and database of high affinity ligands for peptide recognition modules
Published in Molecular systems biology (01-12-2020)“…Many proteins involved in signal transduction contain peptide recognition modules (PRMs) that recognize short linear motifs (SLiMs) within their interaction…”
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Trends in antimicrobial resistance amongst Salmonella Paratyphi A isolates in Bangladesh: 1999-2021
Published in PLoS neglected tropical diseases (01-11-2023)“…Typhoid and paratyphoid remain common bloodstream infections in areas with suboptimal water and sanitation infrastructure. Paratyphoid, caused by Salmonella…”
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10
Identification of a Large Family of Slam-Dependent Surface Lipoproteins in Gram-Negative Bacteria
Published in Frontiers in cellular and infection microbiology (31-05-2017)“…The surfaces of many Gram-negative bacteria are decorated with soluble proteins anchored to the outer membrane via an acylated N-terminus; these proteins are…”
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Mass azithromycin administration: considerations in an increasingly resistant world
Published in BMJ global health (01-06-2020)“…[...]in this essay, we advocate for utmost discretion moving forward and list key considerations that should be taken into account while designing and…”
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New waves, new variants, old inequity: a continuing COVID-19 crisis
Published in BMJ global health (01-08-2021)“…[...]more concerningly, our plight is not unique - low-income and middle-income countries now contribute to a higher proportion of global COVID-19 cases but…”
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COVID-19 rise in Bangladesh correlates with increasing detection of B.1.351 variant
Published in BMJ global health (01-05-2021)“…The variant still shows strong response to antibody treatment and is effectively neutralised by antibodies generated on vaccination by mRNA-based vaccines.4…”
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14
Active Transport of Phosphorylated Carbohydrates Promotes Intestinal Colonization and Transmission of a Bacterial Pathogen
Published in PLoS pathogens (01-08-2015)“…Efficient acquisition of extracellular nutrients is essential for bacterial pathogenesis, however the identities and mechanisms for transport of many of these…”
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15
Code sharing and artificial intelligence can help decolonise public health modelling
Published in BMJ (Online) (09-01-2024)Get more information
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16
A sequence and structure based method to predict putative substrates, functions and regulatory networks of endo proteases
Published in PloS one (27-05-2009)“…Proteases play a central role in cellular homeostasis and are responsible for the spatio-temporal regulation of function. Many putative proteases have been…”
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Substrate-driven assembly of a translocon for multipass membrane proteins
Published in Nature (London) (03-11-2022)“…Most membrane proteins are synthesized on endoplasmic reticulum (ER)-bound ribosomes docked at the translocon, a heterogeneous ensemble of transmembrane…”
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Translocation of lipoproteins to the surface of gram negative bacteria
Published in Current opinion in structural biology (01-08-2018)“…[Display omitted] •Surface lipoproteins or SLPs have been reported in many Gram-negative bacteria.•Different families of SLPs utilize different translocons to…”
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Overcoming colonialism in pathogen genomics
Published in The Lancet. Digital health (01-07-2024)“…Historical legacies of colonialism affect the distribution and control of scientific knowledge today, including within the pathogen genomics field, which…”
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Global landscape of cell envelope protein complexes in Escherichia coli
Published in Nature biotechnology (01-01-2018)“…A survey of cell envelope proteins and their interacting partners in E. coli by mass spectrometry reveals insights into essential bacterial processes…”
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