Search Results - "Hood, D. W."

Lex2B, a Phase-Variable Glycosyltransferase, Adds either a Glucose or a Galactose to Haemophilus influenzae Lipopolysaccharide by Deadman, M.E, Hermant, P, Engskog, M, Makepeace, K, Moxon, E.R, Schweda, E.K.H, Hood, D.W

“…Nontypeable Haemophilus influenzae is a commensal that frequently causes otitis media and respiratory tract infections. The lex2 locus encodes a…”
Get full text

Experimentally revised repertoire of putative contingency loci in Neisseria meningitidis strain MC58: evidence for a novel mechanism of phase variation by Martin, P., Van De Ven, T., Mouchel, N., Jeffries, A. C., Hood, D. W., Moxon, E. R.

“…Summary Analysis of the genome sequence of Neisseria meningitidis strain MC58 revealed 65 genes associated with simple sequence repeats. Experimental evidence…”
Get full text

Repeat‐associated phase variable genes in the complete genome sequence of Neisseria meningitidis strain MC58 by Saunders, Nigel J., Jeffries, Alex C., Peden, John F., Hood, Derek W., Tettelin, Herve, Rappuoli, Rino, Moxon, E. Richard

“…Phase variation, mediated through variation in the length of simple sequence repeats, is recognized as an important mechanism for controlling the expression of…”
Get full text

DNA Repeats Identify Novel Virulence Genes in Haemophilus influenzae by Hood, Derek W., Deadman, Mary E., Jennings, Michael P., Bisercic, Marina, Fleischmann, Robert D., Venter, J. Craig, Moxon, E. Richard

“…The whole genome sequence (1.83 Mbp) of Haemophilus influenzae strain Rd was searched to identify tandem oligonucleotide repeat sequences. Loss or gain of one…”
Get full text

Panel 7 – Pathogenesis of otitis media – a review of the literature between 2015 and 2019 by Thornton, R.B., Hakansson, A., Hood, D.W., Nokso-Koivisto, J., Preciado, D., Riesbeck, K., Richmond, P.C., Su, Y.C., Swords, W.E., Brockman, K.L.

“…To perform a comprehensive review of the literature from July 2015 to June 2019 on the pathogenesis of otitis media. Bacteria, viruses and the role of the…”
Get full text

Signature Tagged Mutagenesis of Haemophilus influenzae identifies genes required for in vivo survival by Herbert, M.A., Hayes, S., Deadman, M.E., Tang, C.M., Hood, D.W., Moxon, E.R.

“…The pathogenic bacterium Haemophilus influenzae causes meningitis, epiglottitis, pneumonia, otitis media and other infections. To further understand the…”
Get full text

Genetic basis for expression of the major globotetraose-containing lipopolysaccharide from H. influenzae strain Rd (RM118) by Hood, D W, Cox, A D, Wakarchuk, W W, Schur, M, Schweda, E K, Walsh, S L, Deadman, M E, Martin, A, Moxon, E R, Richards, J C

“…A genetic basis for the biosynthetic assembly of the globotetraose containing lipopolysaccharide (LPS) of Haemophilus influenzae strain RM118 (Rd) was…”
Get full text

The utility of complete genome sequences in the study of pathogenic bacteria by Hood, D W

“…The availability of complete genome sequences is a revolution in the study of microorganisms. A fully annotated genome sequence provides an interactive tool…”
Get more information

Identification of Vaccine Candidates against Serogroup B Meningococcus by Whole-Genome Sequencing by Pizza, Mariagrazia, Scarlato, Vincenzo, Masignani, Vega, Giuliani, Marzia Monica, Aricò, Beatrice, Comanducci, Maurizio, Jennings, Gary T., Baldi, Lucia, Bartolini, Erika, Capecchi, Barbara, Galeotti, Cesira L., Luzzi, Enrico, Manetti, Roberto, Marchetti, Elisa, Mora, Marirosa, Nuti, Sandra, Ratti, Giulio, Santini, Laura, Savino, Silvana, Scarselli, Maria, Storni, Elisa, Zuo, Peijun, Broeker, Michael, Hundt, Erika, Knapp, Bernard, Blair, Eric, Mason, Tanya, Tettelin, Hervé, Hood, Derek W., Jeffries, Alex C., Saunders, Nigel J., Granoff, Dan M., Venter, J. Craig, Moxon, E. Richard, Grandi, Guido, Rappuoli, Rino

“…Neisseria meningitidis is a major cause of bacterial septicemia and meningitis. Sequence variation of surface-exposed proteins and cross-reactivity of the…”
Get full text

Functional genomics of pathogenic bacteria by Moxon, E. R., Hood, D. W., Saunders, N. J., Schweda, E. K. H., Richards, J. C.

“…lipopolysaccharide and its candidacy as a vaccine…”
Get full text

Complete Genome Sequence of Neisseria meningitidis Serogroup B Strain MC58 by Tettelin, Hervé, Saunders, Nigel J., Heidelberg, John, Jeffries, Alex C., Nelson, Karen E., Eisen, Jonathan A., Ketchum, Karen A., Hood, Derek W., Peden, John F., Dodson, Robert J., Nelson, William C., Gwinn, Michelle L., DeBoy, Robert, Peterson, Jeremy D., Hickey, Erin K., Haft, Daniel H., Salzberg, Steven L., White, Owen, Fleischmann, Robert D., Dougherty, Brian A., Mason, Tanya, Ciecko, Anne, Parksey, Debbie S., Blair, Eric, Cittone, Henry, Clark, Emily B., Cotton, Matthew D., Utterback, Terry R., Khouri, Hoda, Qin, Haiying, Vamathevan, Jessica, Gill, John, Scarlato, Vincenzo, Masignani, Vega, Pizza, Mariagrazia, Grandi, Guido, Sun, Li, Smith, Hamilton O., Fraser, Claire M., Moxon, E. Richard, Rappuoli, Rino, Venter, J. Craig

“…The 2,272,351-base pair genome of Neisseria meningitidis strain MC58 (serogroup B), a causative agent of meningitis and septicemia, contains 2158 predicted…”
Get full text

Simple sequence repeats in Haemophilus influenzae by Power, Peter M., Sweetman, W.A., Gallacher, N.J., Woodhall, M.R., Kumar, G.A., Moxon, E.R., Hood, D.W.

“…Simple sequence repeat (SSRs) of DNA are subject to high rates of mutation and are important mediators of adaptation in Haemophilus influenzae. Previous…”
Get full text

Recombination within Natural Populations of Pathogenic Bacteria: Short-Term Empirical Estimates and Long-Term Phylogenetic Consequences by Feil, Edward J., Holmes, Edward C., Bessen, Debra E., Chan, Man-Suen, Nicholas P. J. Day, Enright, Mark C., Goldstein, Richard, Hood, Derek W., Kalia, Awdhesh, Moore, Catrin E., Zhou, Jiaji, Spratt, Brian G.

“…The identification of clones within bacterial populations is often taken as evidence for a low rate of recombination, but the validity of this inference is…”
Get full text

Molecular genetic analysis of proline and tryptophan biosynthesis in Streptomyces coelicolor A3(2): interaction between primary and secondary metabolism--a review by Hood, D W, Heidstra, R, Swoboda, U K, Hodgson, D A

“…We studied the control of proline metabolism and tryptophan biosynthesis in Streptomyces coelicolor A3(2), because proline is involved in secondary metabolism…”
Get more information

Host-Derived Sialic Acid Is Incorporated into Haemophilus influenzae Lipopolysaccharide and Is a Major Virulence Factor in Experimental Otitis Media by Bouchet, Valérie, Hood, Derek W., Li, Jianjun, Brisson, Jean-Robert, Randle, Gaynor A., Martin, Adèle, Li, Zhong, Goldstein, Richard, Elke K. H. Schweda, Pelton, Stephen I., Richards, James C., Moxon, E. Richard

“…Otitis media, a common and often recurrent bacterial infection of childhood, is a major reason for physician visits and the prescription of antimicrobials…”
Get full text

expression of the trpD, trpC and trpBA genes of Streptomyces coelicolor A3(2) is regulated by growth rate and growth phase but not by feedback repression by Hu, D.S.J, Hood, D.W, Heidstra, R, Hodgson, D.A

“…Transformation of tryptophan auxotrophs of Streptomyces coelicolor A3(2) and subsequent analysis have allowed the identification of four tryptophan…”
Get full text

Haemophilus influenzae lipopolysaccharide by Hood, D W, Richards, J C, Moxon, E R

Get more information

Involvement of genes of genome maintenance in the regulation of phase variation frequencies in Neisseria meningitidis by Martin, Patricia, Sun, Li, Hood, Derek W, Moxon, E. Richard

“…Molecular Infectious Diseases Group, University of Oxford, Department of Paediatrics, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital,…”
Get full text

Haemophilus influence: the impact of whole genome sequencing on microbiology by Tang, Christoph M., Hood, Derek W., Richard Moxon, E.

“…The publication of the Haemophilus influenzae genome sequence in 1995 was a landmark in microbiological research. It has changed our understanding of the…”
Get full text

Phosphorylation of the Lipid A Region of Meningococcal Lipopolysaccharide: Identification of a Family of Transferases That Add Phosphoethanolamine to Lipopolysaccharide by Cox, Andrew D, Wright, J Claire, Li, Jianjun, Hood, Derek W, Moxon, E Richard, Richards, James C

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text