Search Results - "Honrubia, Jose M"
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Role of Severe Acute Respiratory Syndrome Coronavirus Viroporins E, 3a, and 8a in Replication and Pathogenesis
Published in mBio (22-05-2018)“…Viroporins are viral proteins with ion channel (IC) activity that play an important role in several processes, including virus replication and pathogenesis…”
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SARS-CoV-2-Mediated Lung Edema and Replication Are Diminished by Cystic Fibrosis Transmembrane Conductance Regulator Modulators
Published in mBio (28-02-2023)“…Coronaviruses (CoVs) of genera α, β, γ, and δ encode proteins that have a PDZ-binding motif (PBM) consisting of the last four residues of the envelope (E)…”
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Correction for Castaño-Rodriguez et al., "Role of Severe Acute Respiratory Syndrome Coronavirus Viroporins E, 3a, and 8a in Replication and Pathogenesis"
Published in mBio (19-12-2023)Get full text
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Interaction between SARS-CoV PBM and Cellular PDZ Domains Leading to Virus Virulence
Published in Viruses (29-07-2024)“…The interaction between SARS-CoV PDZ-binding motifs (PBMs) and cellular PDZs is responsible for virus virulence. The PBM sequence present in the 3a and…”
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Genetically Engineered Live-Attenuated Middle East Respiratory Syndrome Coronavirus Viruses Confer Full Protection against Lethal Infection
Published in mBio (02-03-2021)“…There are no approved vaccines against the life-threatening Middle East respiratory syndrome coronavirus (MERS-CoV). Attenuated vaccines have proven their…”
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Nature of viruses and pandemics: Coronaviruses
Published in Current research in immunology (01-01-2022)“…Coronaviruses (CoVs) have the largest genome among RNA viruses and store large amounts of information without genome integration as they replicate in the cell…”
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