Search Results - "Honobe‐Tabuchi, Akiko"
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Development of pemphigus vegetans and exacerbation of pemphigus foliaceus after secukinumab loading in a patient with complicated generalized pustular psoriasis and pyoderma gangrenosum
Published in Journal of dermatology (01-02-2023)“…In dermatology, biologics that block signaling pathways of TNF‐α, IL‐4/IL13, IL‐17s, and IL‐23 are widely used for the treatment of several inflammatory skin…”
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Case of bullous pemphigoid refractory to corticosteroids by antiepileptic drug‐induced CYP3A4
Published in Journal of dermatology (01-02-2023)“…The most common treatment option for patients with bullous pemphigoid is systemic corticosteroids. CYP3A4, a drug‐metabolizing enzyme in the liver, metabolizes…”
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Unusual enthesitis in a patient with Behçet’s syndrome
Published in Clinical rheumatology (01-06-2023)Get full text
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4
CD106 in tumor-specific exhausted CD8+ T cells mediates immunosuppression by inhibiting TCR signaling
Published in Cancer research (Chicago, Ill.) (02-07-2024)“…T cell exhaustion is a major contributor to immunosuppression in the tumor microenvironment (TME). Blockade of key regulators of T cell exhaustion, such as…”
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Somatic mutations in tumor-infiltrating lymphocytes impact on antitumor immunity
Published in Proceedings of the National Academy of Sciences - PNAS (27-08-2024)“…Immune checkpoint inhibitors (ICIs) exert clinical efficacy against various types of cancers by reinvigorating exhausted CD8 T cells that can expand and…”
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Mixed Response to Cancer Immunotherapy is Driven by Intratumor Heterogeneity and Differential Interlesion Immune Infiltration
Published in Cancer research communications (28-07-2022)“…Some patients experience mixed response to immunotherapy, whose biological mechanisms and clinical impact have been obscure. We obtained two tumor samples from…”
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Unusual enthesitis in a patient with Behçet's syndrome
Published in Clinical rheumatology (01-06-2023)Get full text
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