Search Results - "Honkanen, Robert A."

Improved MRI methods to quantify retinal and choroidal blood flow applied to a model of glaucoma by Jiang, Zhao, Chernoff, Diane, Galenchik-Chan, Andre, Tomorri, David, Honkanen, Robert A, Duong, Timothy Q, Muir, Eric R

“…Blood flow (BF) of the retinal and choroidal vasculatures can be quantitatively imaged using MRI. This study sought to improve methods of data acquisition and…”
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Animal models of dry eye disease: Useful, varied and evolving (Review) by Huang, Wei, Tourmouzis, Konstantinos, Perry, Henry, Honkanen, Robert A, Rigas, Basil

“…Dry eye disease (DED), which is a prevalent disease that still lacks successful treatment options, remains a major challenge in ophthalmology. Multiple animal…”
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The Antiangiogenic Effect and Ocular Pharmacology of Novel Modified Nonsteroidal Anti-Inflammatory Drugs in the Treatment of Oxygen-Induced Retinopathy by Huang, Wei, Huang, Liqun, Wen, Ziyi, Honkanen, Robert A, Rigas, Basil

“…To evaluate the hypothesis that 3 novel compounds, OXT-328, Q-922, and CL-717 show efficacy in the treatment of oxygen-induced retinopathy (OIR) and whether or…”
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Phosphosulindac is efficacious in an improved concanavalin A-based rabbit model of chronic dry eye disease by Honkanen, Robert A., Huang, Liqun, Xie, Gang, Rigas, Basil

“…Dry eye disease (DED) currently has no satisfactory treatment partly because of the lack of informative animal models. We evaluated the anti-inflammatory…”
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Phospho-Sulindac (OXT-328) Inhibits Dry Eye Disease in Rabbits: A Dose-, Formulation- and Structure-Dependent Effect by Huang, Wei, Wen, Ziyi, Saglam, Muhammet S, Huang, Liqun, Honkanen, Robert A, Rigas, Basil

“…Inflammation of the ocular surface is central to dry eye disease (DED). The anti-inflammatory agent phospho-sulindac (PS) at a high dose was efficacious…”
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Telemedicine at a University Ophthalmology Practice During the Beginning of the COVID-19 Pandemic by Oganov, Anthony C, Chou, Timothy Y, Hanson, Paris M, Abazari, Azin, Kung, Preston, Weissbart, Sarah B, Lenoci, Jacqueline N, Honkanen, Robert A

“…The aim of the research was to evaluate the use of teleophthalmology at a university practice during the COVID-19 pandemic, specifically examining precision,…”
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Heterozygous Triplication of Upstream Regulatory Sequences Leads to Dysregulation of Matrix Metalloproteinase 19 in Patients with Cavitary Optic Disc Anomaly by Hazlewood, Ralph J., Roos, Benjamin R., Solivan-Timpe, Frances, Honkanen, Robert A., Jampol, Lee M., Gieser, Stephen C., Meyer, Kacie J., Mullins, Robert F., Kuehn, Markus H., Scheetz, Todd E., Kwon, Young H., Alward, Wallace L.M., Stone, Edwin M., Fingert, John H.

“…ABSTRACT Patients with a congenital optic nerve disease, cavitary optic disc anomaly (CODA), are born with profound excavation of the optic nerve resembling…”
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A family with Axenfeld–Rieger syndrome and Peters Anomaly caused by a point mutation (Phe112Ser) in the FOXC1 gene by Honkanen, Robert A, Nishimura, Darryl Y, Swiderski, Ruth E, Bennett, Steven R, Hong, Sungpyo, Kwon, Young H, Stone, Edwin M, Sheffield, Val C, Alward, Wallace L.M

“…Mutations of the forkhead transcription factor gene FOXC1 result in anterior segment anomalies. No description of the spectrum of defects resulting from a…”
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Long-term results of eyes with penetrating keratoplasty and glaucoma drainage tube implant by Kwon, Y H, Taylor, J M, Hong, S, Honkanen, R A, Zimmerman, M B, Alward, W L, Sutphin, J E

“…To present long-term results of eyes with penetrating keratoplasty (PK) and glaucoma tube implant. Retrospective, noncomparative, interventional case series…”
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Familial Cavitary Optic Disk Anomalies: Identification of a Novel Genetic Locus by Fingert, John H, Honkanen, Robert A, Shankar, Suma P, Affatigato, Louisa M, Ehlinger, Mary A, Moore, Michael D, Jampol, Lee M, Sheffield, Val C, Stone, Edwin M, Alward, Wallace L.M

“…Purpose To identify the chromosomal location of the gene involved in the pathogenesis of cavitary optic disk anomalies in a large pedigree with autosomal…”
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Familial Cavitary Optic Disk Anomalies: Clinical Features of a Large Family with Examples of Progressive Optic Nerve Head Cupping by Honkanen, Robert A, Jampol, Lee M, Fingert, John H, Moore, Michael D, Taylor, Christine M, Stone, Edwin M, Alward, Wallace L.M

“…Purpose To describe a multigenerational family with autosomal dominant inheritance of cavitary optic nerve head (ONH) anomalies and abnormal ONH vasculature…”
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Ischemic central retinal vein occlusion and neovascular glaucoma as a result of optic nerve head drusen by Honkanen, Robert A, Baba, Fadi El, Sibony, Patrick, Prabhu, Sujata P

“…The purpose of this study was to report a case of ischemic central retinal vein occlusion (CRVO) caused by optic nerve head drusen. Case report and review of…”
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Regulation of the functional expression of hexose transporter GLUT-1 by glucose in murine fibroblasts: role of lysosomal degradation by Ortiz, Phillip A, Honkanen, Robert A, Klingman, David E, Haspel, Howard C

“…The nature of the membrane compartments involved in the regulation by glucose of hexose transport is not well defined. The effect of inhibitors of lysosomal…”
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Correlation of automated visual field parameters and peripapillary nerve fiber layer thickness as measured by scanning laser polarimetry by Kwon, Y H, Hong, S, Honkanen, R A, Alward, W L

“…To correlate Humphrey visual field mean sensitivity and peripapillary nerve fiber layer thickness as measured by scanning laser polarimetry. The authors…”
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Vitreous amino acid concentrations in patients with glaucoma undergoing vitrectomy by Honkanen, Robert A, Baruah, Sankar, Zimmerman, M Bridget, Khanna, Cheryl L, Weaver, Yaffa K, Narkiewicz, Joanna, Waziri, Rafiq, Gehrs, Karen M, Weingeist, Thomas A, Boldt, H Culver, Folk, James C, Russell, Stephen R, Kwon, Young H

“…To measure vitreous concentrations of glutamate and other amino acids in patients with glaucoma undergoing vitrectomy. Undiluted vitreous samples were…”
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Barbiturates Inhibit Hexose Transport in Cultured Mammalian Cells and Human Erythrocytes and Interact Directly with Purified GLUT-1 by Honkanen, Robert A, McBath, Heather, Kushmerick, Christopher, Callender, Gordon E, Scarlata, Suzanne F, Fenstermacher, Joseph D, Haspel, Howard C

“…Barbiturates reduce cerebral blood flow, metabolism, and Glc transfer across the blood-brain barrier. The effect of barbiturates on hexose transport in…”
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Glucose deprivation induces the selective accumulation of hexose transporter protein GLUT-1 in the plasma membrane of normal rat kidney cells by Haspel, H C, Mynarcik, D C, Ortiz, P A, Honkanen, R A, Rosenfeld, M G

“…Antibody to the carboxyl-terminal of hexose transporter protein GLUT-1 was used to localize this carrier in normal rat kidney (NRK) cells during D-glucose…”
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