Search Results - "Hong, Yuning"

A red emitting mitochondria-targeted AIE probe as an indicator for membrane potential and mouse sperm activity by Zhao, Na, Chen, Sijie, Hong, Yuning, Tang, Ben Zhong

“…In this work, a red emission AIE active mitochondrial probe is developed. It is the first non-self-quenching mitochondria specific probe with membrane…”
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Aggregation-Induced Emission: The Whole Is More Brilliant than the Parts by Mei, Ju, Hong, Yuning, Lam, Jacky W. Y., Qin, Anjun, Tang, Youhong, Tang, Ben Zhong

“…“United we stand, divided we fall.”–Aesop.Aggregation‐induced emission (AIE) refers to a photophysical phenomenon shown by a group of luminogenic materials…”
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Barbituric Acid Based Fluorogens: Synthesis, Aggregation-Induced Emission, and Protein Fibril Detection by Ding, Siyang, Yao, Bicheng, Schobben, Louis, Hong, Yuning

“…Fluorescent dyes, especially those emitting in the long wavelength region, are excellent candidates in the area of bioassay and bioimaging. In this work, we…”
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A Ratiometric Fluorescent Probe Based on ESIPT and AIE Processes for Alkaline Phosphatase Activity Assay and Visualization in Living Cells by Song, Zhegang, Kwok, Ryan T. K, Zhao, Engui, He, Zikai, Hong, Yuning, Lam, Jacky W. Y, Liu, Bin, Tang, Ben Zhong

“…Alkaline phosphatase (ALP) activity is regarded as an important biomarker in medical diagnosis. A ratiometric fluorescent probe is developed based on a…”
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A Molecular Chameleon for Mapping Subcellular Polarity in an Unfolded Proteome Environment by Owyong, Tze Cin, Subedi, Pramod, Deng, Jieru, Hinde, Elizabeth, Paxman, Jason J., White, Jonathan M., Chen, Weisan, Heras, Begoña, Wong, Wallace W. H., Hong, Yuning

“…Environmental polarity is an important factor that drives biomolecular interactions to regulate cell function. Herein, a general method of using the…”
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Cytophilic Fluorescent Bioprobes for Long-Term Cell Tracking by Yu, Yong, Feng, Chao, Hong, Yuning, Liu, Jianzhao, Chen, Sijie, Ng, Ka Ming, Luo, Kathy Qian, Tang, Ben Zhong

“…Molecules of siloles are almost non‐fluorescent but their nanoaggregates are highly emissive, exhibiting aggregation‐induced emission (AIE). The AIE‐active…”
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Monitoring Early-Stage Protein Aggregation by an Aggregation-Induced Emission Fluorogen by Kumar, Manjeet, Hong, Yuning, Thorn, David C, Ecroyd, Heath, Carver, John A

“…Highly ordered protein aggregates, termed amyloid fibrils, are associated with a broad range of diseases, many of which are neurodegenerative, for example,…”
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Click chemistry in the design of AIEgens for biosensing and bioimaging by Giel, Marie‐Claire, Hong, Yuning

“…The development of rapid, selective, and sensitive fluorescent sensors is essential for visualizing and quantifying biological molecules and processes in…”
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Full-Range Intracellular pH Sensing by an Aggregation-Induced Emission-Active Two-Channel Ratiometric Fluorogen by Chen, Sijie, Hong, Yuning, Liu, Yang, Liu, Jianzhao, Leung, Chris W. T, Li, Min, Kwok, Ryan T. K, Zhao, Engui, Lam, Jacky W. Y, Yu, Yong, Tang, Ben Zhong

“…Intracellular pH (pHi) is an important parameter associated with cellular behaviors and pathological conditions. Sensing pHi and monitoring its changes in live…”
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Real-Time, Quantitative Lighting-up Detection of Telomerase in Urines of Bladder Cancer Patients by AIEgens by Lou, Xiaoding, Zhuang, Yuan, Zuo, Xiaolei, Jia, Yongmei, Hong, Yuning, Min, Xuehong, Zhang, Zhenyu, Xu, Xuemei, Liu, Nannan, Xia, Fan, Tang, Ben Zhong

“…As a biomarker for early cancer diagnosis, telomerase are one of the promising targets for cancer therapeutics. Inspired by the fluorescent emission principle…”
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A thiol probe for measuring unfolded protein load and proteostasis in cells by Chen, Moore Z., Moily, Nagaraj S., Bridgford, Jessica L., Wood, Rebecca J., Radwan, Mona, Smith, Trevor A., Song, Zhegang, Tang, Ben Zhong, Tilley, Leann, Xu, Xiaohong, Reid, Gavin E., Pouladi, Mahmoud A., Hong, Yuning, Hatters, Danny M.

“…When proteostasis becomes unbalanced, unfolded proteins can accumulate and aggregate. Here we report that the dye, tetraphenylethene maleimide (TPE-MI) can be…”
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Origin of the Conformational Heterogeneity of Cardiolipin-Bound Cytochrome c by Hong, Yuning, Muenzner, Julia, Grimm, Sebastian K, Pletneva, Ekaterina V

“…Interactions of cytochrome c (cyt c) with cardiolipin (CL) partially unfold the protein, activating its peroxidase function, a critical event in the execution…”
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Modest Declines in Proteome Quality Impair Hematopoietic Stem Cell Self-Renewal by Hidalgo San Jose, Lorena, Sunshine, Mary Jean, Dillingham, Christopher H., Chua, Bernadette A., Kruta, Miriama, Hong, Yuning, Hatters, Danny M., Signer, Robert A.J.

“…Low protein synthesis is a feature of somatic stem cells that promotes regeneration in multiple tissues. Modest increases in protein synthesis impair stem cell…”
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Quantitation, Visualization, and Monitoring of Conformational Transitions of Human Serum Albumin by a Tetraphenylethene Derivative with Aggregation-Induced Emission Characteristics by Hong, Yuning, Feng, Chao, Yu, Yong, Liu, Jianzhao, Lam, Jacky Wing Yip, Luo, Kathy Qian, Tang, Ben Zhong

“…Human serum albumin (HSA) is a major protein component of blood plasma, and its assay is of obvious value to biological research. We, herein, present a readily…”
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Becoming a Peroxidase: Cardiolipin-Induced Unfolding of Cytochrome c by Muenzner, Julia, Toffey, Jason R, Hong, Yuning, Pletneva, Ekaterina V

“…Interactions of cytochrome c (cyt c) with a unique mitochondrial glycerophospholipid cardiolipin (CL) are relevant for the protein’s function in oxidative…”
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Deregulated protein homeostasis constrains fetal hematopoietic stem cell pool expansion in Fanconi anemia by Kovuru, Narasaiah, Mochizuki-Kashio, Makiko, Menna, Theresa, Jeffrey, Greer, Hong, Yuning, me Yoon, Young, Zhang, Zhe, Kurre, Peter

“…Demand-adjusted and cell type specific rates of protein synthesis represent an important safeguard for fate and function of long-term hematopoietic stem cells…”
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Notch-induced endoplasmic reticulum-associated degradation governs mouse thymocyte β-selection by Liu, Xia, Yu, Jingjing, Xu, Longyong, Umphred-Wilson, Katharine, Peng, Fanglue, Ding, Yao, Barton, Brendan M, Lv, Xiangdong, Zhao, Michael Y, Sun, Shengyi, Hong, Yuning, Qi, Ling, Adoro, Stanley, Chen, Xi

“…Signals from the pre-T cell receptor and Notch coordinately instruct β-selection of CD4 CD8 double negative (DN) thymocytes to generate αβ T cells in the…”
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Respiratory syncytial virus co-opts host mitochondrial function to favour infectious virus production by Hu, MengJie, Schulze, Keith E, Ghildyal, Reena, Henstridge, Darren C, Kolanowski, Jacek L, New, Elizabeth J, Hong, Yuning, Hsu, Alan C, Hansbro, Philip M, Wark, Peter Ab, Bogoyevitch, Marie A, Jans, David A

“…Although respiratory syncytial virus (RSV) is responsible for more human deaths each year than influenza, its pathogenic mechanisms are poorly understood. Here…”
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Hyperbranched Conjugated Polysiloles: Synthesis, Structure, Aggregation-Enhanced Emission, Multicolor Fluorescent Photopatterning, and Superamplified Detection of Explosives by Liu, Jianzhao, Zhong, Yongchun, Lam, Jacky W. Y, Lu, Ping, Hong, Yuning, Yu, Yong, Yue, Yanan, Faisal, Mahtab, Sung, Herman H. Y, Williams, Ian D, Wong, Kam Sing, Tang, Ben Zhong

“…Hyperbranched poly(2,5-silole)s [hb-P1(m), m = 1, 6] are synthesized for the first time in this work. 1,1-Dialkyl-2,5-bis(4-ethynylphenyl)-3,4-diphenylsiloles…”
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Enhancement of Aggregation-Induced Emission in Dye-Encapsulating Polymeric Micelles for Bioimaging by Wu, Wen-Chung, Chen, Ching-Yi, Tian, Yanqing, Jang, Sei-Hum, Hong, Yuning, Liu, Yang, Hu, Rongrong, Tang, Ben Zhong, Lee, Yi-Ting, Chen, Chin-Ti, Chen, Wen-Chang, Jen, Alex K.-Y.

“…Three amphiphilic block copolymers are employed to form polymeric micelles and function as nanocarriers to disperse hydrophobic aggregation‐induced emission…”
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