Search Results - "Hong, Yu Ah"
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Resveratrol Ameliorates Contrast Induced Nephropathy Through the Activation of SIRT1-PGC-1α-Foxo1 Signaling in Mice
Published in Kidney & blood pressure research (01-01-2017)“…Background/Aims: SIRT1 activation promotes the resistance of renal tubular cells to oxidative stress, and resveratrol is known as a SIRT1 activator. Methods:…”
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Clinical outcomes of infection-related hospitalization in incident peritoneal dialysis patients
Published in Kidney research and clinical practice (01-12-2020)“…Infection is the second leading cause of death in patients undergoing long-term dialysis. Peritoneal dialysis (PD) is associated with an increased risk of…”
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The Role of Sirtuins in Kidney Diseases
Published in International journal of molecular sciences (12-09-2020)“…Sirtuins (SIRTs) are class III histone deacetylases (HDACs) that play important roles in aging and a wide range of cellular functions. Sirtuins are crucial to…”
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Are older adults safe and suitable candidate donors or recipients for kidney transplantation?
Published in Kidney research and clinical practice (01-05-2022)“…KCI Citation Count: 0…”
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5
Catalytic Antioxidants in the Kidney
Published in Antioxidants (18-01-2021)“…Reactive oxygen species and reactive nitrogen species are highly implicated in kidney injuries that include acute kidney injury, chronic kidney disease,…”
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Assessment of tubular reabsorption of phosphate as a surrogate marker for phosphate regulation in chronic kidney disease
Published in Clinical and experimental nephrology (01-04-2015)“…Background/Aims Fibroblast growth factor 23 (FGF23) and soluble α-Klotho are emerging potential biomarkers of phosphorus and vitamin D metabolism which change…”
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Xanthine oxidoreductase inhibition ameliorates high glucose-induced glomerular endothelial injury by activating AMPK through the purine salvage pathway
Published in Scientific reports (15-05-2024)“…Xanthine oxidoreductase (XOR) contributes to reactive oxygen species production. We investigated the cytoprotective mechanisms of XOR inhibition against high…”
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Inhibition of Xanthine Oxidase Protects against Diabetic Kidney Disease through the Amelioration of Oxidative Stress via VEGF/VEGFR Axis and NOX-FoxO3a-eNOS Signaling Pathway
Published in International journal of molecular sciences (01-02-2023)“…Xanthine oxidase (XO) is an important source of reactive oxygen species. This study investigated whether XO inhibition exerts renoprotective effects by…”
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Adiponectin receptor agonist ameliorates cardiac lipotoxicity via enhancing ceramide metabolism in type 2 diabetic mice
Published in Cell death & disease (30-03-2022)“…Accumulation of lipids and their metabolites induces lipotoxicity in diabetic cardiomyopathy. Lowering ceramide concentration could reduce the impact of…”
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Trends and outcome of statin therapy in dialysis patients with atherosclerotic cardiovascular diseases: A population-based cohort study
Published in PloS one (02-06-2023)“…Although statins are an effective strategy for the secondary prevention of atherosclerotic cardiovascular disease (ASCVD) in the general population, the…”
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Fenofibrate improves renal lipotoxicity through activation of AMPK-PGC-1α in db/db mice
Published in PloS one (06-05-2014)“…Peroxisome proliferator-activated receptor (PPAR)-α, a lipid-sensing transcriptional factor, serves an important role in lipotoxicity. We evaluated whether…”
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Inhibition of lymphatic proliferation by the selective VEGFR-3 inhibitor SAR131675 ameliorates diabetic nephropathy in db/db mice
Published in Cell death & disease (04-03-2019)“…Recent studies have demonstrated that chronic inflammation-induced lymphangiogenesis plays a crucial role in the progression of various renal diseases,…”
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Clinical significance of neutrophil-to-lymphocyte ratio on the risk of abdominal aortic calcification and decreased bone mineral density in patients with end-stage kidney disease
Published in PloS one (25-10-2023)“…Inflammation plays a major role in the pathogenesis of chronic kidney disease (CKD), but the relationship between systemic inflammation and CKD-mineral bone…”
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Radiocontrast-induced nephropathy is attenuated by autophagy through regulation of apoptosis and inflammation
Published in Human & experimental toxicology (01-07-2016)“…Radiocontrast-induced nephropathy (RCN) is the third most common cause of acute renal failure among inpatients. Although the number of patients undergoing…”
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Trends in epidemiologic characteristics of end-stage renal disease from 2019 Korean Renal Data System (KORDS)
Published in Kidney research and clinical practice (01-03-2021)“…The Korean Society of Nephrology (KSN) has maintained a nationwide end-stage renal disease (ESRD) registry data from Korean Renal Data System (KORDS) since…”
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Importance of dialysis specialists in early mortality in elderly hemodialysis patients: a multicenter retrospective cohort study
Published in Scientific reports (22-01-2024)“…The early mortality rate in elderly patients undergoing hemodialysis is more than twice that in young patients, requiring more specialized healthcare. We…”
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Cilastatin Preconditioning Attenuates Renal Ischemia-Reperfusion Injury via Hypoxia Inducible Factor-1α Activation
Published in International journal of molecular sciences (19-05-2020)“…Cilastatin is a specific inhibitor of renal dehydrodipeptidase-1. We investigated whether cilastatin preconditioning attenuates renal ischemia-reperfusion (IR)…”
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Association between physical activity and risk of renal function decline and mortality in community-dwelling older adults: a nationwide population-based cohort study
Published in BMC geriatrics (17-12-2022)“…Physical activity (PA) is an important risk factor associated with health outcomes. However, the relationship between PA and kidney function decline in older…”
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The Effect of Strict Volume Control Assessed by Repeated Bioimpedance Spectroscopy on Cardiac Function in Peritoneal Dialysis Patients
Published in Scientific reports (27-11-2019)“…Adequate fluid management plays an important role in decreasing cardiovascular risk in peritoneal dialysis (PD) patients. We evaluated whether strict volume…”
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