Search Results - "Hong, Yean Ju"

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  1. 1

    Altered Mitochondrial Function and Accelerated Aging Phenotype in Neural Stem Cells Derived from Dnm1l Knockout Embryonic Stem Cells by Na, Seung-Bin, Seo, Bong-Jong, Hong, Tae-Kyung, Oh, Seung-Yeon, Hong, Yean-Ju, Song, Jae-Hoon, Uhm, Sang-Jun, Hong, Kwonho, Do, Jeong-Tae

    “…Mitochondria are crucial for cellular energy metabolism and are involved in signaling, aging, and cell death. They undergo dynamic changes through fusion and…”
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    Journal Article
  2. 2

    Distinct Enhancer Activity of Oct4 in Naive and Primed Mouse Pluripotency by Choi, Hyun Woo, Joo, Jin Young, Hong, Yean Ju, Kim, Jong Soo, Song, Hyuk, Lee, Jeong Woong, Wu, Guangming, Schöler, Hans R., Do, Jeong Tae

    Published in Stem cell reports (08-11-2016)
    “…Naive and primed pluripotent stem cells (PSCs) and germ cells express the Oct4 gene. The Oct4 gene contains two cis-regulatory elements, the distal enhancer…”
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  3. 3

    DJ-1 Can Replace FGF-2 for Long-Term Culture of Human Pluripotent Stem Cells in Defined Media and Feeder-Free Condition by Kim, Julee, Baek, Sangki, Hong, Yean Ju, de Paula, Michelle Novais, Jahan Prima, Musharrat, Oh, Yeon-Mok, Cha, Sun-Shin, Do, Jeong Tae, Jang, Yeon Jin, Choe, Han

    “…Conventional human pluripotent stem cell (hPSC) cultures require high concentrations of expensive human fibroblast growth factor 2 (hFGF-2) for hPSC…”
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  4. 4

    Developmental Potency and Metabolic Traits of Extended Pluripotency Are Faithfully Transferred to Somatic Cells via Cell Fusion-Induced Reprogramming by Song, Jae-Hoon, Choi, Joonhyuk, Hong, Yean-Ju, La, Hyeonwoo, Hong, Tae-Kyung, Hong, Kwonho, Do, Jeong-Tae

    Published in Cells (Basel, Switzerland) (01-10-2022)
    “…As a novel cell type from eight-cell-stage embryos, extended pluripotent stem cells (EPSCs) are known for diverse differentiation potency in both…”
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  5. 5

    Acceleration of Mesenchymal-to-Epithelial Transition (MET) during Direct Reprogramming Using Natural Compounds by Seo, Ji-Hye, Jang, Si Won, Jeon, Young-Joo, Eun, So Young, Hong, Yean Ju, Do, Jeong Tae, Chae, Jung-il, Choi, Hyun Woo

    Published in Journal of microbiology and biotechnology (31-10-2022)
    “…Induced pluripotent stem cells (iPSCs) can be generated from somatic cells using Oct4, Sox2, Klf4, and c-Myc (OSKM). Small molecules can enhance reprogramming…”
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    Journal Article
  6. 6

    Neural Lineage Differentiation From Pluripotent Stem Cells to Mimic Human Brain Tissues by Hong, Yean Ju, Do, Jeong Tae

    “…Recent advances in induced pluripotent stem cell (iPSC) research have turned limitations of prior and current research into possibilities. iPSCs can…”
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  7. 7

    Cellular Reprogramming Using Protein and Cell-Penetrating Peptides by Seo, Bong Jong, Hong, Yean Ju, Do, Jeong Tae

    “…Recently, stem cells have been suggested as invaluable tools for cell therapy because of their self-renewal and multilineage differentiation potential. Thus,…”
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  8. 8

    Mitochondrial and metabolic remodeling during reprogramming and differentiation of the reprogrammed cells by Choi, Hyun Woo, Kim, Jin Hoi, Chung, Mi Kyung, Hong, Yean Ju, Jang, Hyun Sik, Seo, Bong Jong, Jung, Taek Hee, Kim, Jong Soo, Chung, Hyung Min, Byun, Sung June, Han, Sung Gu, Seo, Han Geuk, Do, Jeong Tae

    Published in Stem cells and development (01-06-2015)
    “…Reprogramming is one of the most essential areas of research in stem cell biology. Despite this importance, the mechanism and correlates of reprogramming…”
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  9. 9

    Comparative analysis of the mitochondrial morphology, energy metabolism, and gene expression signatures in three types of blastocyst-derived stem cells by Choi, Joonhyuk, Seo, Bong Jong, La, Hyeonwoo, Yoon, Sang Hoon, Hong, Yean Ju, Lee, Ji-Heon, Chung, Hyung-Min, Hong, Kwonho, Do, Jeong Tae

    Published in Redox biology (01-02-2020)
    “…Pre-implantation mouse blastocyst-derived stem cells, namely embryonic stem cells (ESCs), trophoblast stem cells (TSCs), and extraembryonic endoderm (XEN)…”
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  10. 10

    In vivo differentiation of induced pluripotent stem cells into neural stem cells by chimera formation by Choi, Hyun Woo, Hong, Yean Ju, Kim, Jong Soo, Song, Hyuk, Cho, Ssang Gu, Bae, Hojae, Kim, Changsung, Byun, Sung June, Do, Jeong Tae

    Published in PloS one (31-01-2017)
    “…Like embryonic stem cells, induced pluripotent stem cells (iPSCs) can differentiate into all three germ layers in an in vitro system. Here, we developed a new…”
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  11. 11

    Integrative analysis of mitochondrial metabolic dynamics in reprogramming human fibroblast cells by Cha, Young, Leblanc, Pierre, Hong, Yean Ju, Kim, Kwang-Soo

    Published in STAR protocols (17-06-2022)
    “…Mitochondrial dynamics play critical roles in both tissue homeostasis and somatic cell reprogramming. Here, we provide integrated guidance for assessing…”
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    Journal Article
  12. 12

    Changes in the Expression of Mitochondrial Morphology-Related Genes during the Differentiation of Murine Embryonic Stem Cells by Do, Jeong-Tae, Song, Hyuk, Hong, Kwonho, Hong, Yean Ju, Han, Min Ji, Seo, Bong Jong, Lee, Jeong Eon, Lee, Jeong-Woong

    Published in Stem cells international (2020)
    “…During embryonic development, cells undergo changes in gene expression, signaling pathway activation/inactivation, metabolism, and intracellular organelle…”
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  13. 13

    Mitochondrial Remodeling in Chicken Induced Pluripotent Stem-Like Cells by Choi, Hyun Woo, Kim, Jong Soo, Choi, Sol, Ju Hong, Yean, Byun, Sung June, Seo, Han Geuk, Do, Jeong Tae

    Published in Stem cells and development (15-03-2016)
    “…Chicken pluripotent stem cells (PSCs), such as embryonic stem cells and blastoderm cells, have been used to study development and differentiation in chicken…”
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  14. 14

    Generation of brain organoids from mouse ESCs via teratoma formation by Lee, Won Ji, Lee, Jeong Eon, Hong, Yean Ju, Yoon, Sang Hoon, Song, Hyuk, Park, Chankyu, Hong, Kwonho, Choi, Youngsok, Do, Jeong Tae

    Published in Stem cell research (01-12-2020)
    “…[Display omitted] •Sox1-GFP transgenic embryonic stem cells (ESCs) can be used for brain organoid formation.•Isolated Sox1-GFP+ cells from teratoma can be used…”
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  15. 15

    Generation of Partially Reprogrammed Cells and Fully Reprogrammed iPS Cells by Plasmid Transfection by Kim, Jong Soo, Choi, Hyun Woo, Hong, Yean Ju, Do, Jeong Tae

    “…Induced pluripotent stem (iPS) cells can be directly generated from somatic cells by overexpression of defined transcription factors. iPS cells can perpetually…”
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  16. 16

    Changes in Parthenogenetic Imprinting Patterns during Reprogramming by Cell Fusion by Jang, Hyun Sik, Hong, Yean Ju, Choi, Hyun Woo, Song, Hyuk, Byun, Sung June, Uhm, Sang Jun, Seo, Han Geuk, Do, Jeong Tae

    Published in PloS one (27-05-2016)
    “…Differentiated somatic cells can be reprogrammed into the pluripotent state by cell-cell fusion. In the pluripotent state, reprogrammed cells may then…”
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  17. 17

    Neural Stem Cells Differentiated From iPS Cells Spontaneously Regain Pluripotency by Choi, Hyun Woo, Kim, Jong Soo, Choi, Sol, Hong, Yean Ju, Kim, Min Jung, Seo, Han Geuk, Do, Jeong Tae

    Published in Stem cells (Dayton, Ohio) (01-10-2014)
    “…Differentiated somatic cells can be reprogrammed into pluripotent stem cells by transduction of exogenous reprogramming factors. After induced pluripotent stem…”
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  18. 18

    Inhibition of neural stem cell aging through the transient induction of reprogramming factors by Han, Min Ji, Lee, Won Ji, Choi, Joonhyuk, Hong, Yean Ju, Uhm, Sang Jun, Choi, Youngsok, Do, Jeong Tae

    Published in Journal of comparative neurology (1911) (01-02-2021)
    “…Adult stem cells age during long‐term in vitro culture, and neural stem cells (NSCs), which can self‐renew and differentiate into neurons and glial cells, also…”
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  19. 19

    A Simple Method for Generating Cerebral Organoids from Human Pluripotent Stem Cells by Hong, Yean Ju, Lee, So Been, Choi, Joonhyuk, Yoon, Sang Hoon, Do, Jeong Tae

    Published in International journal of stem cells (28-02-2022)
    “…In recent years, brain organoid technologies have been the most innovative advance in neural differentiation research. In line with this, we optimized a method…”
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