Search Results - "Hong, Yean Ju"
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1
Altered Mitochondrial Function and Accelerated Aging Phenotype in Neural Stem Cells Derived from Dnm1l Knockout Embryonic Stem Cells
Published in International journal of molecular sciences (01-09-2023)“…Mitochondria are crucial for cellular energy metabolism and are involved in signaling, aging, and cell death. They undergo dynamic changes through fusion and…”
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2
Distinct Enhancer Activity of Oct4 in Naive and Primed Mouse Pluripotency
Published in Stem cell reports (08-11-2016)“…Naive and primed pluripotent stem cells (PSCs) and germ cells express the Oct4 gene. The Oct4 gene contains two cis-regulatory elements, the distal enhancer…”
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3
DJ-1 Can Replace FGF-2 for Long-Term Culture of Human Pluripotent Stem Cells in Defined Media and Feeder-Free Condition
Published in International journal of molecular sciences (31-05-2021)“…Conventional human pluripotent stem cell (hPSC) cultures require high concentrations of expensive human fibroblast growth factor 2 (hFGF-2) for hPSC…”
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4
Developmental Potency and Metabolic Traits of Extended Pluripotency Are Faithfully Transferred to Somatic Cells via Cell Fusion-Induced Reprogramming
Published in Cells (Basel, Switzerland) (01-10-2022)“…As a novel cell type from eight-cell-stage embryos, extended pluripotent stem cells (EPSCs) are known for diverse differentiation potency in both…”
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Acceleration of Mesenchymal-to-Epithelial Transition (MET) during Direct Reprogramming Using Natural Compounds
Published in Journal of microbiology and biotechnology (31-10-2022)“…Induced pluripotent stem cells (iPSCs) can be generated from somatic cells using Oct4, Sox2, Klf4, and c-Myc (OSKM). Small molecules can enhance reprogramming…”
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6
Neural Lineage Differentiation From Pluripotent Stem Cells to Mimic Human Brain Tissues
Published in Frontiers in bioengineering and biotechnology (06-12-2019)“…Recent advances in induced pluripotent stem cell (iPSC) research have turned limitations of prior and current research into possibilities. iPSCs can…”
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7
Cellular Reprogramming Using Protein and Cell-Penetrating Peptides
Published in International journal of molecular sciences (03-03-2017)“…Recently, stem cells have been suggested as invaluable tools for cell therapy because of their self-renewal and multilineage differentiation potential. Thus,…”
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8
Mitochondrial and metabolic remodeling during reprogramming and differentiation of the reprogrammed cells
Published in Stem cells and development (01-06-2015)“…Reprogramming is one of the most essential areas of research in stem cell biology. Despite this importance, the mechanism and correlates of reprogramming…”
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9
Comparative analysis of the mitochondrial morphology, energy metabolism, and gene expression signatures in three types of blastocyst-derived stem cells
Published in Redox biology (01-02-2020)“…Pre-implantation mouse blastocyst-derived stem cells, namely embryonic stem cells (ESCs), trophoblast stem cells (TSCs), and extraembryonic endoderm (XEN)…”
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10
In vivo differentiation of induced pluripotent stem cells into neural stem cells by chimera formation
Published in PloS one (31-01-2017)“…Like embryonic stem cells, induced pluripotent stem cells (iPSCs) can differentiate into all three germ layers in an in vitro system. Here, we developed a new…”
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11
Integrative analysis of mitochondrial metabolic dynamics in reprogramming human fibroblast cells
Published in STAR protocols (17-06-2022)“…Mitochondrial dynamics play critical roles in both tissue homeostasis and somatic cell reprogramming. Here, we provide integrated guidance for assessing…”
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12
Changes in the Expression of Mitochondrial Morphology-Related Genes during the Differentiation of Murine Embryonic Stem Cells
Published in Stem cells international (2020)“…During embryonic development, cells undergo changes in gene expression, signaling pathway activation/inactivation, metabolism, and intracellular organelle…”
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13
Mitochondrial Remodeling in Chicken Induced Pluripotent Stem-Like Cells
Published in Stem cells and development (15-03-2016)“…Chicken pluripotent stem cells (PSCs), such as embryonic stem cells and blastoderm cells, have been used to study development and differentiation in chicken…”
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14
Generation of brain organoids from mouse ESCs via teratoma formation
Published in Stem cell research (01-12-2020)“…[Display omitted] •Sox1-GFP transgenic embryonic stem cells (ESCs) can be used for brain organoid formation.•Isolated Sox1-GFP+ cells from teratoma can be used…”
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15
Generation of Partially Reprogrammed Cells and Fully Reprogrammed iPS Cells by Plasmid Transfection
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2016)“…Induced pluripotent stem (iPS) cells can be directly generated from somatic cells by overexpression of defined transcription factors. iPS cells can perpetually…”
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16
Changes in Parthenogenetic Imprinting Patterns during Reprogramming by Cell Fusion
Published in PloS one (27-05-2016)“…Differentiated somatic cells can be reprogrammed into the pluripotent state by cell-cell fusion. In the pluripotent state, reprogrammed cells may then…”
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Neural Stem Cells Differentiated From iPS Cells Spontaneously Regain Pluripotency
Published in Stem cells (Dayton, Ohio) (01-10-2014)“…Differentiated somatic cells can be reprogrammed into pluripotent stem cells by transduction of exogenous reprogramming factors. After induced pluripotent stem…”
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18
Inhibition of neural stem cell aging through the transient induction of reprogramming factors
Published in Journal of comparative neurology (1911) (01-02-2021)“…Adult stem cells age during long‐term in vitro culture, and neural stem cells (NSCs), which can self‐renew and differentiate into neurons and glial cells, also…”
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A Simple Method for Generating Cerebral Organoids from Human Pluripotent Stem Cells
Published in International journal of stem cells (28-02-2022)“…In recent years, brain organoid technologies have been the most innovative advance in neural differentiation research. In line with this, we optimized a method…”
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Erratum to: Acceleration of Mesenchymal-to-Epithelial Transition (MET) during Direct Reprogramming Using Natural Compounds
Published in Journal of microbiology and biotechnology (28-12-2022)Get full text
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