Search Results - "Hong, Tianpei"

Dapagliflozin promotes beta cell regeneration by inducing pancreatic endocrine cell phenotype conversion in type 2 diabetic mice by Wei, Rui, Cui, Xiaona, Feng, Jin, Gu, Liangbiao, Lang, Shan, Wei, Tianjiao, Yang, Jin, Liu, Junling, Le, Yunyi, Wang, Haining, Yang, Kun, Hong, Tianpei

“…Clinical trials and animal studies have shown that sodium-glucose co-transporter type 2 (SGLT2) inhibitors improve pancreatic beta cell function. Our study…”
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CAPTURE: a multinational, cross-sectional study of cardiovascular disease prevalence in adults with type 2 diabetes across 13 countries by Mosenzon, Ofri, Alguwaihes, Abdullah, Leon, Jose Luis Arenas, Bayram, Fahri, Darmon, Patrice, Davis, Timothy M E, Dieuzeide, Guillermo, Eriksen, Kirsten T, Hong, Tianpei, Kaltoft, Margit S, Lengyel, Csaba, Rhee, Nicolai A, Russo, Giuseppina T, Shirabe, Shinichiro, Urbancova, Katerina, Vencio, Sergio

“…There is a paucity of global data on cardiovascular disease (CVD) prevalence in people with type 2 diabetes (T2D). The primary objective of the CAPTURE study…”
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Coexistence of type 2 diabetes mellitus, arginine vasopressin deficiency, and Marfan syndrome: A case report by Le, Yunyi, Zhang, Jingjing, Hong, Tianpei, Yang, Jin

“…Diabetes mellitus (DM) and arginine vasopressin deficiency (AVP‐D) are characterized by polyuria. Marfan syndrome is an autosomal dominant disorder caused by…”
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Recurrent hypoglycemia induced by clopidogrel: A case report and mini review by Du, Weiguan, Wang, Haining, Liu, Ye, Hong, Tianpei

“…This report describes a patient who developed recurrent hypoglycemia episodes after 23 days of antiplatelet therapy with clopidogrel for left subclavian artery…”
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Exenatide exerts direct protective effects on endothelial cells through the AMPK/Akt/eNOS pathway in a GLP-1 receptor-dependent manner by Wei, Rui, Ma, Shifeng, Wang, Chen, Ke, Jing, Yang, Jin, Li, Weihong, Liu, Ye, Hou, Wenfang, Feng, Xinheng, Wang, Guang, Hong, Tianpei

“…Glucagon-like peptide-1 (GLP-1) may have direct favorable effects on cardiovascular system. The aim of this study was to investigate the effects of the GLP-1…”
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Delineating the transcriptional atlas for impaired insulin secretion: A window into type 2 diabetes pathophysiology by Li, Jian, Yang, Jin, Hong, Tianpei

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Positive feedback regulation between glycolysis and histone lactylation drives oncogenesis in pancreatic ductal adenocarcinoma by Li, Fei, Si, Wenzhe, Xia, Li, Yin, Deshan, Wei, Tianjiao, Tao, Ming, Cui, Xiaona, Yang, Jin, Hong, Tianpei, Wei, Rui

“…Metabolic reprogramming and epigenetic alterations contribute to the aggressiveness of pancreatic ductal adenocarcinoma (PDAC). Lactate-dependent histone…”
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MTA2-mediated inhibition of PTEN leads to pancreatic ductal adenocarcinoma carcinogenicity by Si, Wenzhe, Liu, Xujun, Wei, Rui, Zhang, Yuan, Zhao, Yang, Cui, Liyan, Hong, Tianpei

“…Metastasis-associated protein 2 (MTA2) is a core subunit of the nucleosome remodeling and deacetylating (NuRD) complex and functions by mediating chromatin…”
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γ-aminobutyric acid modulates α-cell hyperplasia but not β-cell regeneration induced by glucagon receptor antagonism in type 1 diabetic mice by Gu, Liangbiao, Cui, Xiaona, Lin, Xiafang, Yang, Jin, Wei, Rui, Hong, Tianpei, Yang, Kun

“…Aims To investigate whether treatment with γ -aminobutyric acid (GABA) alone or in combination with glucagon receptor (GCGR) monoclonal antibody (mAb) exerted…”
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High Vitamin D Level in Female Mice Increases the Number of Live Fetuses by LIU, Guoqiang, YANG, Kun, LE, Yunyi, WEI, Rui, HONG, Tianpei, YANG, Jin

“…Little is known about the impact of high-normal range of 25-hydroxyvitamin D [25(OH)D] on reproductive function. The aim of this study was to investigate the…”
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Synergistic anti-tumor effects of liraglutide with metformin on pancreatic cancer cells by Lu, Ran, Yang, Jin, Wei, Rui, Ke, Jing, Tian, Qing, Yu, Fei, Liu, Junling, Zhang, Jingjing, Hong, Tianpei

“…Either metformin or liraglutide has been reported to have anti-tumor effects on pancreatic cancer cells. However, it is not clear whether their combined…”
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脂肪酸β‐氧化和线粒体融合参与胰高血糖素受体拮抗剂对糖尿病小鼠心脏微血管内皮细胞的保护作用 by Wang, Peng, Wei, Rui, Cui, Xiaona, Jiang, Zongzhe, Yang, Jin, Zu, Lingyun, Hong, Tianpei

“…摘要 介绍:心脏微血管内皮细胞(CMECs)在糖尿病心肌病中的作用尚未完全清楚。我们的目的是研究胰高血糖素受体(GCGR)单克隆抗体(mAb)是否改善了糖尿病心肌病，并阐明CMECs是否以及如何参与这一过程 方法: GCGR…”
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Diabetes, even newly defined by HbA1c testing, is associated with an increased risk of in-hospital death in adults with COVID-19 by Liu, Ye, Lu, Ran, Wang, Junhong, Cheng, Qin, Zhang, Ruitao, Zhang, Shuisheng, Le, Yunyi, Wang, Haining, Xiao, Wenhua, Gao, Hongwei, Zeng, Lin, Hong, Tianpei

“…Diabetes is associated with poor coronavirus disease 2019 (COVID-19) outcomes. However, little is known on the impact of undiagnosed diabetes in the COVID-19…”
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Metformin attenuates fluctuating glucose-induced endothelial dysfunction through enhancing GTPCH1-mediated eNOS recoupling and inhibiting NADPH oxidase by An, Huijie, Wei, Rui, Ke, Jing, Yang, Jin, Liu, Ye, Wang, Xian, Wang, Guang, Hong, Tianpei

“…Abstract Aims The aim of this study was to investigate whether and how metformin ameliorated endothelial dysfunction induced by fluctuating glucose (FG) in…”
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Cardiovascular risk profile and clinical characteristics of diabetic patients: a cross-sectional study in China by Lyu, Fang, Cai, Xiaoling, Lin, Chu, Hong, Tianpei, Zhang, Xiaomei, Lu, Juming, Guo, Xiaohui, Wang, Zhufeng, Xing, Huifang, Zong, Guizhi, Ji, Linong

“…Cardiovascular (CV) disease is the leading cause of morbidity and mortality in adults with type 2 diabetes (T2D). The aim of this study was to determine the CV…”
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Impact of polyethylene glycol loxenatide on cardiovascular outcomes in patients with type 2 diabetes: study protocol for a multicentre, randomised, double-blind, placebo-controlled trial (BALANCE-3) by Xie, Yun, Kuang, Jian, Li, Quanmin, Hong, Tianpei, Ji, Linong, Kong, Yuanyuan, Duan, Yale, Chen, Liming

“…IntroductionRecent cardiovascular outcomes trials have demonstrated that glucagon-like peptide 1 receptor agonist (GLP-1RA) decreases the incidence of major…”
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High baseline FGF21 levels are associated with poor glucose-lowering efficacy of exenatide in patients with type 2 diabetes by Yang, Kun, Wang, Haining, Wei, Rui, Xiao, Wenhua, Tian, Qing, Wang, Chen, Yang, Jin, Hong, Tianpei

“…Aims To investigate the association between fibroblast growth factor 21 (FGF21) levels and glycemic response to exenatide in patients with type 2 diabetes…”
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Identification of key genes and pathways in mild and severe nonalcoholic fatty liver disease by integrative analysis by Feng, Jin, Wei, Tianjiao, Cui, Xiaona, Wei, Rui, Hong, Tianpei

“…The global prevalence of nonalcoholic fatty liver disease (NAFLD) is increasing. The pathogenesis of NAFLD is multifaceted, and the underlying mechanisms are…”
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Regeneration of β cells from cell phenotype conversion among the pancreatic endocrine cells by Wei, Tianjiao, Wei, Rui, Hong, Tianpei

“…In both type 1 and type 2 diabetes, pancreatic islet β cell dysfunction is common pathogenesis and substantial decrease in β cell mass can induce clinical…”
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GLP-1 receptor agonists stimulate ANGPTL8 production through the PI3K/Akt pathway in a GLP-1 receptor-dependent manner by Liu, Junling, Yang, Kun, Xiao, Wenhua, Le, Yunyi, Lang, Shan, Zhang, Jingjing, Wei, Rui, Yang, Jin, Hong, Tianpei

“…•Exenatide treatment increased serum ANGPTL8 level in patients with T2DM.•Upregulation of serum ANGPTL8 level is not associated with BW loss and BG…”
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