Search Results - "Hong, Siting"

H3 relaxin inhibits the collagen synthesis via ROS‐ and P2X7R‐mediated NLRP3 inflammasome activation in cardiac fibroblasts under high glucose by Zhang, Xiaohui, Fu, Yu, Li, Hui, Shen, Li, Chang, Qing, Pan, Liya, Hong, Siting, Yin, Xinhua

“…Excessive production of reactive oxygen species (ROS) and P2X7R activation induced by high glucose increases NLRP3 inflammasome activation, which contributes…”
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IL-10 partly mediates the ability of MSC-derived extracellular vesicles to attenuate myocardial damage in experimental metabolic renovascular hypertension by Jiang, Yamei, Hong, Siting, Zhu, Xiangyang, Zhang, Lei, Tang, Hui, Jordan, Kyra L, Saadiq, Ishran M, Huang, Weijun, Lerman, Amir, Eirin, Alfonso, Lerman, Lilach O

“…Extracellular vesicles (EVs) obtain properties of immunomodulation and tissue repair from their parental mesenchymal stem cells (MSCs), and upon delivery may…”
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H3 Relaxin Protects Against Myocardial Injury in Experimental Diabetic Cardiomyopathy by Inhibiting Myocardial Apoptosis, Fibrosis and Inflammation by Zhang, Xiaohui, Pan, Liya, Yang, Kelaier, Fu, Yu, Liu, Yue, Chi, Jinyu, Zhang, Xin, Hong, Siting, Ma , Xiao, Yin, Xinhua

“…Background/Aims: Apoptosis, fibrosis and NLRP3 inflammasome activation are involved in the development of diabetic cardiomyopathy (DCM). Human recombinant…”
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NLRP3 Inflammasome Is Involved in Calcium-Sensing Receptor-Induced Aortic Remodeling in SHRs by Yin, Xinhua, Zhao, Meng, Shi, Zhiyu, Zhang, Xiaohui, Liu, Wenxiu, Qi, Shuhan, Hong, Siting, Zhang, Xin, Chen, Wenjia

“…Increasing evidence suggests that the NLRP3 (nucleotide oligomerization domain-like receptor family, pyrin domain containing 3) inflammasome participates in…”
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Role of the calcium sensing receptor in cardiomyocyte apoptosis via mitochondrial dynamics in compensatory hypertrophied myocardium of spontaneously hypertensive rat by Hong, Siting, Zhang, Xin, Zhang, Xiaohui, Liu, Wenxiu, Fu, Yu, Liu, Yue, Shi, Zhiyu, Chi, Jinyu, Zhao, Meng, Yin, Xinhua

“…Calcium sensing receptor (CaSR) mediates pathological cardiac hypertrophy. Mitochondria maintain their function through fission and fusion and disruption of…”
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Effects of Elamipretide on Autophagy in Renal Cells of Pigs with Metabolic Syndrome by Hong, Siting, Ghandriz, Ramyar, Siddiqi, Sarosh, Zhu, Xiang-Yang, Saadiq, Ishran M, Jordan, Kyra L, Tang, Hui, Ali, Khaled A, Lerman, Amir, Eirin, Alfonso, Lerman, Lilach O

“…Autophagy eliminates excessive nutrients and maintains homeostasis. Obesity and metabolic syndrome (MetS) dysregulate autophagy, possibly partly due to…”
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Obesity blunts amelioration of cardiac hypertrophy and fibrosis by human mesenchymal stem/stromal cell-derived extracellular vesicles by Hong, Siting, Huang, Weijun, Zhu, Xiangyang, Tang, Hui, Krier, James D, Xing, Li, Lu, Bo, Gandhi, Deep, Jordan, Kyra L, Saadiq, Ishran M, Lerman, Amir, Eirin, Alfonso, Lerman, Lilach O

“…Renovascular hypertension (RVH) can induce cardiac damage that is reversible using adipose tissue-derived mesenchymal stromal/stem cells (A-MSCs). However,…”
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Protective Role of (-)-Epicatechin on Trimethylamine-N-Oxide (TMAO)-Induced Cardiac Hypertrophy via SP1/SIRT1/SUMO1 Signaling Pathway by Hong, Siting, Lu, Jing, Li, Jiaoyan, Luo, Yingchun, Liu, Dongxue, Jin, Yuanyuan, Wang, Zeng, Wang, Yibo, Zhang, Hao, Zhang, Xin, Li, Yang, Zhang, Haoruo, Dong, Zengxiang, Wang, Zhaojun, Lv, Lin, Liang, Zhaoguang

“…(-)-Epicatechin (EPI) is beneficial for cardiovascular health. Trimethylamine N-oxide (TMAO), a gut microbe-derived food metabolite, is strongly associated…”
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Involvement of mitochondrial fission in calcium sensing receptor-mediated vascular smooth muscle cells proliferation during hypertension by Zhang, Xin, Chen, Wenjia, Li, Jiawen, Qi, Shuhan, Hong, Siting, Wang, Ying, Gao, Lei, Shi, Zhiyu, Liu, Yue, Liu, Wenxiu, Chi, Yinyu, Liu, Chunnan, Fu, Yu, Yin, Xinhua

“…Hyperproliferation of vascular smooth muscle cells (VSMC) is a major risk factor for cardiovascular diseases. Proper mitochondrial fission and fusion is…”
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Salt reduction and hypertension in China: a concise state-of-the-art review by Liu, Yue, Li, Huiyan, Hong, Siting, Yin, Xinhua

“…Hypertension (HTN) and its cardiovascular complications such as stroke and heart failure are a serious public health problem around the world. A growing number…”
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Autologous Extracellular Vesicles Attenuate Cardiac Injury in Experimental Atherosclerotic Renovascular Disease More Effectively Than Their Parent Mesenchymal Stem/Stromal Cells by Hong, Siting, Zhu, Xiang-Yang, Jiang, Yamei, Zhang, Lei, Tang, Hui, Jordan, Kyra L, Saadiq, Ishran M, Huang, Weijun, Lerman, Amir, Eirin, Alfonso, Lerman, Lilach O

“…Atherosclerotic renovascular disease (RVD) leads to hypertension, chronic kidney disease (CKD), and heart disease. Intrarenal delivery of mesenchymal stem…”
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Obesity Blunts the Effect of Mesenchymal Stem Cell-Derived Extracellular Vesicles by Huang, Weijun, Hong, Siting, Zhu, Xiangyang, Alsaeedi, Mina H., Tang, Hui, Krier, James D., Gandhi, Deep, Jordan, Kyra L., Saadiq, Ishran M., Jiang, Yamei, Eirin, Alfonso, Lerman, Lilach O.

“…Mesenchymal stem/stromal cell-derived extracellular vesicles (MSC-EVs) are paracrine vectors with therapeutic functions comparable to their parent cells…”
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