Search Results - "Hong, Lixin"
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Role of Hippo signaling in regulating immunity
Published in Cellular & molecular immunology (01-12-2018)“…The Hippo signaling pathway has been established as a key regulator of organ size control, tumor suppression, and tissue regeneration in multiple organisms…”
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2
CD36 facilitates fatty acid uptake by dynamic palmitoylation-regulated endocytosis
Published in Nature communications (21-09-2020)“…Fatty acids (FAs) are essential nutrients, but how they are transported into cells remains unclear. Here, we show that FAs trigger caveolae-dependent CD36…”
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3
TLR4 signalling via Piezo1 engages and enhances the macrophage mediated host response during bacterial infection
Published in Nature communications (10-06-2021)“…TLR4 signaling plays key roles in the innate immune response to microbial infection. Innate immune cells encounter different mechanical cues in both health and…”
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4
Macrophage achieves self-protection against oxidative stress-induced ageing through the Mst-Nrf2 axis
Published in Nature communications (14-02-2019)“…Reactive oxygen species (ROS) production in phagocytes is a major defense mechanism against pathogens. However, the cellular self-protective mechanism against…”
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Effects of Nd on microstructure and mechanical properties of as-cast Mg-12Gd-2Zn-xNd-0.4Zr alloys with stacking faults
Published in International journal of minerals, metallurgy and materials (01-08-2022)“…In order to study the effects of Nd addition on microstructure and mechanical properties of Mg-Gd-Zn-Zr alloys, the microstructure and mechanical properties of…”
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6
Pharmacological targeting of kinases MST1 and MST2 augments tissue repair and regeneration
Published in Science translational medicine (17-08-2016)“…Tissue repair and regenerative medicine address the important medical needs to replace damaged tissue with functional tissue. Most regenerative medicine…”
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Participation of the p38 pathway in Drosophila host defense against pathogenic bacteria and fungi
Published in Proceedings of the National Academy of Sciences - PNAS (30-11-2010)“…The signaling network of innate immunity in Drosophila is constructed by multiple evolutionarily conserved pathways, including the Toll- or Imd-regulated NF-κB…”
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8
Attenuation of TORC1 signaling delays replicative and oncogenic RAS-induced senescence
Published in Cell cycle (Georgetown, Tex.) (15-06-2012)“…Numerous stimuli, including oncogenic signaling, DNA damage or eroded telomeres trigger proliferative arrest, termed cellular senescence. Accumulating evidence…”
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The miR-17-92 Cluster of MicroRNAs Confers Tumorigenicity by Inhibiting Oncogene-Induced Senescence
Published in Cancer research (Chicago, Ill.) (01-11-2010)“…In mammalian cells, activation of oncogenes usually triggers innate tumor-suppressing defense mechanisms, including apoptosis and senescence, which are…”
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10
The Hippo signaling pathway in liver regeneration and tumorigenesis
Published in Acta biochimica et biophysica Sinica (01-01-2015)“…The Hippo signaling pathway is an evolutionarily conserved signaling module that plays critical roles in liver size control and tumorigenesis. The Hippo…”
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SPTAN1/NUMB axis senses cell density to restrain cell growth and oncogenesis through Hippo signaling
Published in The Journal of clinical investigation (15-10-2023)“…The loss of contact inhibition is a key step during carcinogenesis. The Hippo-Yes-associated protein (Hippo/YAP) pathway is an important regulator of cell…”
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A Novel Function of p38-Regulated/Activated Kinase in Endothelial Cell Migration and Tumor Angiogenesis
Published in Molecular and Cellular Biology (01-02-2012)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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13
The transcriptional coactivator TAZ regulates reciprocal differentiation of TH17 cells and Treg cells
Published in Nature immunology (01-07-2017)“…Hippo signaling controls cell and tissue growth. Geng et al . show that Hippo signaling is required for T H 17 cell differentiation but inhibits T reg cell…”
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14
Current Status and Progress of Specific Laboratory Examination Methods of Active Tuberculosis Infection Diagnosis
Published in Nano biomedicine and engineering (30-03-2018)“…Active tuberculosis infection is a major health concern in the world. Each year, millions of people die of tuberculosis, especially in third-world countries…”
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15
Epithelial p38alpha controls immune cell recruitment in the colonic mucosa
Published in PLoS pathogens (03-06-2010)“…Intestinal epithelial cells (IECs) compose the first barrier against microorganisms in the gastrointestinal tract. Although the NF-kappaB pathway in IECs was…”
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The Role of Nd in Corrosion Properties of Mg-12Gd-2Zn-0.4Zr Alloys
Published in Journal of materials engineering and performance (01-08-2021)“…To reveal the effect of Nd addition on corrosion properties of Mg-Gd-Zn-Zr alloys, the corrosion behavior of the as-cast Mg-12Gd-2Zn- x Nd-0.4Zr ( x = 0, 0.5,…”
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17
Diastereo- and Enantioselective Dearomative Reductive Aryl-Fluoroalkenylation of Indoles by Nickel Catalysis
Published in ACS catalysis (03-05-2024)“…Herein, we disclose a nickel-catalyzed dearomative reductive aryl-fluoroalkenylation of indoles by defluorinative coupling with gem-difluoroalkenes. The…”
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18
Glycogen accumulation and phase separation drives liver tumor initiation
Published in Cell (28-10-2021)“…Glucose consumption is generally increased in tumor cells to support tumor growth. Interestingly, we report that glycogen accumulation is a key initiating…”
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Effects of Solution Temperature and Nd Addition on Microstructure and Mechanical Properties of Mg-12Gd-2Zn-xNd-0.4Zr Alloys
Published in Journal of materials engineering and performance (01-09-2024)“…To reveal the influences of solution temperature and Nd addition on microstructures and mechanical properties of Mg-12Gd-2Zn- x Nd-0.4Zr ( x = 0, 0.5, and…”
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20
The transcriptional coactivator TAZ regulates reciprocal differentiation of T H 17 cells and T reg cells
Published in Nature immunology (01-07-2017)“…An imbalance in the lineages of immunosuppressive regulatory T cells (T cells) and the inflammatory T 17 subset of helper T cells leads to the development of…”
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