Search Results - "Hong, Kyeong Man"

Monitoring circulating tumor DNA by analyzing personalized cancer-specific rearrangements to detect recurrence in gastric cancer by Kim, Young-Woo, Kim, Young-Ho, Song, Yura, Kim, Han-Seong, Sim, Hye Won, Poojan, Shiv, Eom, Bang Wool, Kook, Myeong-Cherl, Joo, Jungnam, Hong, Kyeong-Man

“…Circulating tumor DNA (ctDNA) has emerged as a candidate biomarker for cancer screening. However, studies on the usefulness of ctDNA for postoperative…”
Get full text

Oncogene-induced senescence mediated by c-Myc requires USP10 dependent deubiquitination and stabilization of p14ARF by Ko, Aram, Han, Su Yeon, Choi, Chel Hun, Cho, Hanbyoul, Lee, Min-Sik, Kim, Soo-Youl, Song, Joon Seon, Hong, Kyeong-Man, Lee, Han-Woong, Hewitt, Stephen M., Chung, Joon-Yong, Song, Jaewhan

“…Oncogene-induced senescence (OIS) is a critical tumor-suppressor mechanism, which prevents hyper-proliferation and transformation of cells. c-Myc promotes OIS…”
Get full text

CCL3L3-null status is associated with susceptibility to systemic lupus erythematosus by Kim, Young-Ho, Lee, Eunyoung Emily, Sim, Hye-Won, Kang, Eun-Kyung, Won, Yoon-Ho, Lee, Dong-eun, Hong, Kyeong-Man, Song, Yeong-Wook

“…The correlation between copy number variation (CNV) and the susceptibility to systemic lupus erythematosus (SLE) has been reported for various immunity-related…”
Get full text

False-negative errors in next-generation sequencing contribute substantially to inconsistency of mutation databases by Kim, Young-Ho, Song, Yura, Kim, Jong-Kwang, Kim, Tae-Min, Sim, Hye Won, Kim, Hyung-Lae, Jang, Hyonchol, Kim, Young-Woo, Hong, Kyeong-Man

“…More than 11,000 laboratories and companies developed their own next-generation sequencing (NGS) for screening and diagnosis of various diseases including…”
Get full text

Cancer cells undergoing epigenetic transition show short-term resistance and are transformed into cells with medium-term resistance by drug treatment by Poojan, Shiv, Bae, Seung-Hyun, Min, Jae-Woong, Lee, Eun Young, Song, Yura, Kim, Hee Yeon, Sim, Hye Won, Kang, Eun-Kyung, Kim, Young-Ho, Lee, Hae-Ock, Hong, Yourae, Park, Woong-Yang, Jang, Hyonchol, Hong, Kyeong-Man

“…To elucidate the epigenetic mechanisms of drug resistance, epigenetically reprogrammed H460 cancer cells (R-H460) were established by the transient…”
Get full text

Effects of deranged metabolism on epigenetic changes in cancer by Chandra, Vishal, Hong, Kyeong-Man

“…The concept of epigenetics is now providing the mechanisms by which cells transfer their new environmental-change-induced phenotypes to their daughter cells…”
Get full text

CKAP2 (cytoskeleton-associated protein2) is a new prognostic marker in HER2-negative luminal type breast cancer by Sim, Sung Hoon, Bae, Chang-Dae, Kwon, Youngmi, Hwang, Hai-Li, Poojan, Shiv, Hong, Hye-In, Kim, Kyungtae, Kang, Seo-Hee, Kim, Han-Seong, Um, Tae-Hyun, Park, In Hae, Lee, Keun Seok, Jung, So-Youn, Lee, Seeyoun, Kang, Han-Sung, Lee, Eun Sook, Kim, Mi-Kyung, Hong, Kyeong-Man, Ro, Jungsil

“…Recently, we reported cytoskeleton-associated protein2 (CKAP2) as a possible new prognostic breast cancer marker. However, it has not yet been applied in…”
Get full text

Reply to Krupenko et al. Comment on “Lee et al. The Combination of Loss of ALDH1L1 Function and Phenformin Treatment Decreases Tumor Growth in KRAS-Driven Lung Cancer Cancers 2020, 12, 1382” by Lee, Seon-Hyeong, Jeon, Yoon, Kang, Joon-Hee, Jang, Hyonchol, Hong, Kyeong-Man, Hong, Dongwan, Lee, Ho, Kim, Soo-Youl

“…In the Cancers paper, we observed the increase ALDH1L1 protein expression following oncogenesis, as well as a therapeutic effect, by deleting the Aldh1l1 gene…”
Get full text

FAK -Copy-Gain Is a Predictive Marker for Sensitivity to FAK Inhibition in Breast Cancer by Kim, Young-Ho, Kim, Hyun-Kyoung, Kim, Hee Yeon, Gawk, HyeRan, Bae, Seung-Hyun, Sim, Hye Won, Kang, Eun-Kyung, Seoh, Ju-Young, Jang, Hyonchol, Hong, Kyeong-Man

“…Cancers with copy-gain drug-target genes are excellent candidates for targeted therapy. In order to search for new predictive marker genes, we investigated the…”
Get full text

Association of polymorphisms and haplotypes in the insulin-like growth factor 1 receptor (IGF1R) gene with the risk of breast cancer in Korean women by Kang, Han-Sung, Ahn, Sei Hyun, Mishra, Siddhartha Kumar, Hong, Kyeong-Man, Lee, Eun Sook, Shin, Kyung Hwan, Ro, Jungsil, Lee, Keun Seok, Kim, Mi Kyung

“…The insulin-like growth factor (IGF) signaling pathway plays an important role in cancer biology. The IGF 1 receptor (IGF1R) overexpression has been associated…”
Get full text

Chromatin CKAP2, a new proliferation marker, as independent prognostic indicator in breast cancer by Kim, Han-Seong, Koh, Jae-Soo, Choi, Yong-Bock, Ro, Jungsil, Kim, Hyun-Kyoung, Kim, Mi-Kyung, Nam, Byung-Ho, Kim, Kyung-Tae, Chandra, Vishal, Seol, Hye-Sil, Noh, Woo-Chul, Kim, Eun-Kyu, Park, Joobae, Bae, Chang-Dae, Hong, Kyeong-Man

“…The level of proliferation activity is a strong prognostic or predictive indicator in breast cancer, but its optimal measurement is still in debate,…”
Get full text

Mutations in the Tyrosine Kinase Domain of the Epidermal Growth Factor Receptor in Non–Small Cell Lung Cancer by SEI HOON YANG, MECHANIC, Leah E, FUKUOKA, Junya, TRAVIS, William, CAPORASO, Neil E, HARRIS, Curtis C, JIN JEN, PING YANG, LANDI, Maria Teresa, BOWMAN, Elise D, WAMPFLER, Jason, MEERZAMAN, Daoud, KYEONG MAN HONG, MANN, Felicia, DRACHEVA, Tatiana

“…We evaluated somatic genetic alterations in the kinase domain of the EGFR gene in the tumors of 219 non–small cell lung cancer patients of primarily Caucasian…”
Get full text

Transglutaminase 2 as an independent prognostic marker for survival of patients with non-adenocarcinoma subtype of non-small cell lung cancer by Choi, Chang-Min, Jang, Se-Jin, Park, Seong-Yeol, Choi, Yong-Bock, Jeong, Jae-Heon, Kim, Dae-Seok, Kim, Hyun-Kyoung, Park, Kang-Seo, Nam, Byung-Ho, Kim, Hyeong-Ryul, Kim, Soo-Youl, Hong, Kyeong-Man

“…Expression of transglutaminase 2 (TGase 2) is related to invasion and resistance to chemotherapeutic agents in several cancer cells. However, there has been…”
Get full text

Simple and versatile molecular method of copy-number measurement using cloned competitors by Kim, Hyun-Kyoung, Hwang, Hai-Li, Park, Seong-Yeol, Lee, Kwang Man, Park, Won Cheol, Kim, Han-Seong, Um, Tae-Hyun, Hong, Young Jun, Lee, Jin Kyung, Joo, Sun-Young, Seoh, Ju-Young, Song, Yeong-Wook, Kim, Soo-Youl, Kim, Yong-Nyun, Hong, Kyeong-Man

“…Variations and alterations of copy numbers (CNVs and CNAs) carry disease susceptibility and drug responsiveness implications. Although there are many molecular…”
Get full text

Targeted next-generation sequencing at copy-number breakpoints for personalized analysis of rearranged ends in solid tumors by Kim, Hyun-Kyoung, Park, Won Cheol, Lee, Kwang Man, Hwang, Hai-Li, Park, Seong-Yeol, Sorn, Sungbin, Chandra, Vishal, Kim, Kwang Gi, Yoon, Woong-Bae, Bae, Joon Seol, Shin, Hyoung Doo, Shin, Jong-Yeon, Seoh, Ju-Young, Kim, Jong-Il, Hong, Kyeong-Man

“…The concept of the utilization of rearranged ends for development of personalized biomarkers has attracted much attention owing to its clinical applicability…”
Get full text

Ectopic Overexpression of Coiled-Coil Domain Containing 110 Delays G2/M Entry in U2-OS Cells by Lee, Sue Nyoung, Hong, Kyeong-Man, Seong, Yeon Sun, Kwak, Sahng-June

“…Coiled-coil domain containing 110 (CCDC110, KM-HN-1) is a protein containing C-terminal coiled-coil domain (CCD) which was previously discovered as a member of…”
Get full text

Cdk1-Cyclin B1-mediated Phosphorylation of Tumor-associated Microtubule-associated Protein/Cytoskeleton-associated Protein 2 in Mitosis by Hong, Kyung Uk, Kim, Hyun-Jun, Kim, Hyo-Sil, Seong, Yeon-Sun, Hong, Kyeong-Man, Bae, Chang-Dae, Park, Joobae

“…During mitosis, establishment of structurally and functionally sound bipolar spindles is necessary for maintaining the fidelity of chromosome segregation…”
Get full text

Zinc finger protein 143 expression is closely related to tumor malignancy via regulating cell motility in breast cancer by Paek, A Rome, Mun, Ji Young, Hong, Kyeong-Man, Lee, Jongkeun, Hong, Dong Wan, You, Hye Jin

“…We previously reported the involvement of zinc-finger protein 143 (ZNF143) on cancer cell motility in colon cancer cells. Here, ZNF143 was further…”
Get full text

Down-regulation of lipid raft-associated onco-proteins via cholesterol-dependent lipid raft internalization in docosahexaenoic acid-induced apoptosis by Lee, Eun Jeong, Yun, Un-Jung, Koo, Kyung Hee, Sung, Jee Young, Shim, Jaegal, Ye, Sang-Kyu, Hong, Kyeong-Man, Kim, Yong-Nyun

“…Lipid rafts, plasma membrane microdomains, are important for cell survival signaling and cholesterol is a critical lipid component for lipid raft integrity and…”
Get full text

Inactivation of LLC1 gene in nonsmall cell lung cancer by Hong, Kyeong‐Man, Yang, Sei‐Hoon, Chowdhuri, Sinchita Roy, Player, Audrey, Hames, Megan, Fukuoka, Junya, Meerzaman, Daoud, Dracheva, Tatiana, Sun, Zhifu, Yang, Ping, Jen, Jin

“…Serial analysis of gene expression studies led us to identify a previously unknown gene, c20orf85, that is present in the normal lung epithelium but absent or…”
Get full text