Search Results - "Hong, Jason Y."

CRISPR Interference-Based Platform for Multimodal Genetic Screens in Human iPSC-Derived Neurons by Tian, Ruilin, Gachechiladze, Mariam A., Ludwig, Connor H., Laurie, Matthew T., Hong, Jason Y., Nathaniel, Diane, Prabhu, Anika V., Fernandopulle, Michael S., Patel, Rajan, Abshari, Mehrnoosh, Ward, Michael E., Kampmann, Martin

“…CRISPR/Cas9-based functional genomics have transformed our ability to elucidate mammalian cell biology. However, most previous CRISPR-based screens were…”
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Compromised function of the ESCRT pathway promotes endolysosomal escape of tau seeds and propagation of tau aggregation by Chen, John J., Nathaniel, Diane L., Raghavan, Preethi, Nelson, Maxine, Tian, Ruilin, Tse, Eric, Hong, Jason Y., See, Stephanie K., Mok, Sue-Ann, Hein, Marco Y., Southworth, Daniel R., Grinberg, Lea T., Gestwicki, Jason E., Leonetti, Manuel D., Kampmann, Martin

“…Intercellular propagation of protein aggregation is emerging as a key mechanism in the progression of several neurodegenerative diseases, including Alzheimer's…”
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