Search Results - "Hong, Jason S."

Mitochondrial Transfer by Photothermal Nanoblade Restores Metabolite Profile in Mammalian Cells by Wu, Ting-Hsiang, Sagullo, Enrico, Case, Dana, Zheng, Xin, Li, Yanjing, Hong, Jason S., TeSlaa, Tara, Patananan, Alexander N., McCaffery, J. Michael, Niazi, Kayvan, Braas, Daniel, Koehler, Carla M., Graeber, Thomas G., Chiou, Pei-Yu, Teitell, Michael A.

“…mtDNA sequence alterations are challenging to generate but desirable for basic studies and potential correction of mtDNA diseases. Here, we report a new method…”
Get full text

UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells by Zhang, Jin, Khvorostov, Ivan, Hong, Jason S, Oktay, Yavuz, Vergnes, Laurent, Nuebel, Esther, Wahjudi, Paulin N, Setoguchi, Kiyoko, Wang, Geng, Do, Anna, Jung, Hea-Jin, McCaffery, J Michael, Kurland, Irwin J, Reue, Karen, Lee, Wai-Nang P, Koehler, Carla M, Teitell, Michael A

“…It has been assumed, based largely on morphologic evidence, that human pluripotent stem cells (hPSCs) contain underdeveloped, bioenergetically inactive…”
Get full text

Measuring energy metabolism in cultured cells, including human pluripotent stem cells and differentiated cells by Zhang, Jin, Nuebel, Esther, Wisidagama, Dona R R, Setoguchi, Kiyoko, Hong, Jason S, Van Horn, Christine M, Imam, Sarah S, Vergnes, Laurent, Malone, Cindy S, Koehler, Carla M, Teitell, Michael A

“…Measurements of glycolysis and mitochondrial function are required to quantify energy metabolism in a wide variety of cellular contexts. In human pluripotent…”
Get full text

Intracellular Photothermal Delivery for Suspension Cells Using Sharp Nanoscale Tips in Microwells by Man, Tianxing, Zhu, Xiongfeng, Chow, Yu Ting, Dawson, Emma R, Wen, Ximiao, Patananan, Alexander N, Liu, Tingyi Leo, Zhao, Chuanzhen, Wu, Cong, Hong, Jason S, Chung, Pei-Shan, Clemens, Daniel L, Lee, Bai-Yu, Weiss, Paul S, Teitell, Michael A, Chiou, Pei-Yu

“…Efficient intracellular delivery of biomolecules into cells that grow in suspension is of great interest for biomedical research, such as for applications in…”
Get full text

Correcting human mitochondrial mutations with targeted RNA import by Wang, Geng, Shimada, Eriko, Zhang, Jin, Hong, Jason S, Smith, Geoffrey M, Teitell, Michael A, Koehler, Carla M

“…Mutations in the human mitochondrial genome are implicated in neuromuscular diseases, metabolic defects, and aging. An efficient and simple mechanism for…”
Get full text

Rapid, Massively Parallel Single-Cell Drug Response Measurements via Live Cell Interferometry by Reed, Jason, Chun, Jennifer, Zangle, Thomas A., Kalim, Sheraz, Hong, Jason S., Pefley, Sarah E., Zheng, Xin, Gimzewski, James K., Teitell, Michael A.

“…A central question in cancer therapy is how individual cells within a population of tumor cells respond to drugs designed to arrest their growth. However, the…”
Get full text

A Mutation in PNPT1, Encoding Mitochondrial-RNA-Import Protein PNPase, Causes Hereditary Hearing Loss by VON AMELN, Simon, GENG WANG, BORCK, Guntram, HONG, Jason S, GOODYEAR, Richard J, ABIDI, Omar, NÜRNBERG, Peter, HOFMANN, Kay, RICHARDSON, Guy P, HAMMERSCHMIDT, Matthias, MOSER, Tobias, WOLLNIK, Bernd, BOULOUIZ, Redouane, KOEHLER, Carla M, TEITELL, Michael A, BARAKAT, Abdelhamid, KUBISCH, Christian, RUTHERFORD, Mark A, SMITH, Geoffrey M, YUN LI, POGODA, Hans-Martin, NIIRNBERG, Gudrun, STILLER, Barbara, VOLK, Alexander E

“…A subset of nuclear-encoded RNAs has to be imported into mitochondria for the proper replication and transcription of the mitochondrial genome and, hence, for…”
Get full text

AID-Induced Genotoxic Stress Promotes B Cell Differentiation in the Germinal Center via ATM and LKB1 Signaling by Sherman, Mara H., Kuraishy, Ali I., Deshpande, Chetan, Hong, Jason S., Cacalano, Nicholas A., Gatti, Richard A., Manis, John P., Damore, Michael A., Pellegrini, Matteo, Teitell, Michael A.

“…During an immune response, B cells undergo rapid proliferation and activation-induced cytidine deaminase (AID)-dependent remodeling of immunoglobulin (IG)…”
Get full text

Mammalian Polynucleotide Phosphorylase Is an Intermembrane Space RNase That Maintains Mitochondrial Homeostasis by Chen, Hsiao-Wen, Rainey, Robert N., Balatoni, Cynthia E., Dawson, David W., Troke, Joshua J., Wasiak, Sylwia, Hong, Jason S., McBride, Heidi M., Koehler, Carla M., Teitell, Michael A., French, Samuel W.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Expression of sprouty2 inhibits B-cell proliferation and is epigenetically silenced in mouse and human B-cell lymphomas by Frank, Matthew J., Dawson, David W., Bensinger, Steven J., Hong, Jason S., Knosp, Wendy M., Xu, Lizhong, Balatoni, Cynthia E., Allen, Eric L., Shen, Rhine R., Bar-Sagi, Dafna, Martin, Gail R., Teitell, Michael A.

“…B-cell lymphoma is the most common immune system malignancy. TCL1 transgenic mice (TCL1-tg), in which TCL1 is ectopically expressed in mature lymphocytes,…”
Get full text

PNPASE Regulates RNA Import into Mitochondria by Wang, Geng, Chen, Hsiao-Wen, Oktay, Yavuz, Zhang, Jin, Allen, Eric L., Smith, Geoffrey M., Fan, Kelly C., Hong, Jason S., French, Samuel W., McCaffery, J. Michael, Lightowlers, Robert N., Morse, Herbert C., Koehler, Carla M., Teitell, Michael A.

“…RNA import into mammalian mitochondria is considered essential for replication, transcription, and translation of the mitochondrial genome but the pathway(s)…”
Get full text

Restriction landmark genomic scanning (RLGS) spot identification by second generation virtual RLGS in multiple genomes with multiple enzyme combinations by Smiraglia, Dominic J, Kazhiyur-Mannar, Ramakrishnan, Oakes, Christopher C, Wu, Yue-Zhong, Liang, Ping, Ansari, Tahmina, Su, Jian, Rush, Laura J, Smith, Laura T, Yu, Li, Liu, Chunhui, Dai, Zunyan, Chen, Shih-Shih, Wang, Shu-Huei, Costello, Joseph, Ioshikhes, Ilya, Dawson, David W, Hong, Jason S, Teitell, Michael A, Szafranek, Angela, Camoriano, Marta, Song, Fei, Elliott, Rosemary, Held, William, Trasler, Jacquetta M, Plass, Christoph, Wenger, Rephael

“…Restriction landmark genomic scanning (RLGS) is one of the most successfully applied methods for the identification of aberrant CpG island hypermethylation in…”
Get full text

Ampk regulates IgD expression but not energy stress with B cell activation by Waters, Lynnea R., Ahsan, Fasih M., ten Hoeve, Johanna, Hong, Jason S., Kim, Diane N. H., Minasyan, Aspram, Braas, Daniel, Graeber, Thomas G., Zangle, Thomas A., Teitell, Michael A.

“…Ampk is an energy gatekeeper that responds to decreases in ATP by inhibiting energy-consuming anabolic processes and promoting energy-generating catabolic…”
Get full text

UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells by Zhang, Jin, Khvorostov, Ivan, Hong, Jason S, Oktay, Yavuz, Vergnes, Laurent, Nuebel, Esther, Wahjudi, Paulin N, Setoguchi, Kiyoko, Wang, Geng, Do, Anna, Jung, Hea-Jin, McCaffery, J Michael, Kurland, Irwin J, Reue, Karen, Lee, Wai-Nang P, Koehler, Carla M, Teitell, Michael A

Get full text

Epigenetic Silencing of Stk39 in B-Cell Lymphoma Inhibits Apoptosis from Genotoxic Stress by Balatoni, Cynthia E, Dawson, David W, Suh, Jane, Sherman, Mara H, Sanders, Grant, Hong, Jason S, Frank, Matthew J, Malone, Cindy S, Said, Jonathan W, Teitell, Michael A

“…B-cell lymphomas, the most frequent human immune system malignancies, often contain dysregulated TCL1 oncogene expression. TCL1 transgenic (TCL1-tg) mice…”
Get full text

CRTC2 Regulates Plasma Cell Metabolism and Survival to Maintain Humoral Immune Responses by Hong, Jason S

“…The humoral immune response is mediated by antigen activated B cells that have terminally differentiated into antibody secreting cells (ASCs). The ASC pool is…”
Get full text

Mitochondrial Transfer by Photothermal Nanoblade Restores Respiration in Mammalian Cells with Dysfunctional Mitochondria by Patananan, Alexander N., Wu, Ting-Hsiang, Sagullo, Enrico, Case, Dana, Zheng, Xin, Li, Yanjing, Hong, Jason S., TeSlaa, Tara, McCaffery, J. Michael, Niazi, Kayvan, Braas, Daniel, Koehler, Carla M., Graeber, Thomas G., Chiou, Pei-Yu, Teitell, Michael A.

Get full text

Erratum To: UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells by Zhang, Jin, Khvorostov, Ivan, Hong, Jason S, Oktay, Yavuz, Vergnes, Laurent, Nuebel, Esther, Wahjudi, Paulin N, Setoguchi, Kiyoko, Wang, Geng, Do, Anna, Jung, Hea‐Jin, McCaffery, J Michael, Kurland, Irwin J, Reue, Karen, Lee, Wai‐Nang P, Koehler, Carla M, Teitell, Michael A

“…Graphical Abstract…”
Get full text

UCP 2 regulates energy metabolism and differentiation potential of human pluripotent stem cells by Zhang, Jin, Khvorostov, Ivan, Hong, Jason S, Oktay, Yavuz, Vergnes, Laurent, Nuebel, Esther, Wahjudi, Paulin N, Setoguchi, Kiyoko, Wang, Geng, Do, Anna, Jung, Hea‐Jin, McCaffery, J Michael, Kurland, Irwin J, Reue, Karen, Lee, Wai‐Nang P, Koehler, Carla M, Teitell, Michael A

Get full text

UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells: UCP2 regulates hPSC metabolism and differentiation by Zhang, Jin, Khvorostov, Ivan, Hong, Jason S, Oktay, Yavuz, Vergnes, Laurent, Nuebel, Esther, Wahjudi, Paulin N, Setoguchi, Kiyoko, Wang, Geng, Do, Anna, Jung, Hea-Jin, McCaffery, J Michael, Kurland, Irwin J, Reue, Karen, Lee, Wai-Nang P, Koehler, Carla M, Teitell, Michael A

Get full text