Search Results - "Hong, Hyowon"

Actin remodeling confers BRAF inhibitor resistance to melanoma cells through YAP/TAZ activation by Kim, Min Hwan, Kim, Jongshin, Hong, Hyowon, Lee, Si-Hyung, Lee, June-Koo, Jung, Eunji, Kim, Joon

“…The activation of transcriptional coactivators YAP and its paralog TAZ has been shown to promote resistance to anti‐cancer therapies. YAP/TAZ activity is…”
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Myosin heavy chain 10 (MYH10) is required for centriole migration during the biogenesis of primary cilia by Hong, Hyowon, Kim, Jongshin, Kim, Joon

“…The actin cytoskeleton has been implicated in the assembly of cilia, but roles of actin-dependent motor proteins in ciliogenesis remain unclear. Myosin heavy…”
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Export of membrane proteins from the Golgi complex to the primary cilium requires the kinesin motor, KIFC1 by Lee, Si‐Hyung, Too, Kwangsic, Jung, Eun Ji, Hong, Hyowon, Seo, Jimyung, Kim, Joon

“…Microtubule‐based motors contribute to the efficiency and selectivity of Golgi exit and post‐Golgi transport of membrane proteins that are targeted to distinct…”
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Discovery of GSK3β Inhibitors through In Silico Prediction-and-Experiment Cycling Strategy, and Biological Evaluation by Lee, Yuno, Yoon, Sae-Bom, Hong, Hyowon, Kim, Hyun Young, Jung, Daeyoung, Moon, Byoung-San, Park, Woo-Kyu, Lee, Sunkyung, Kwon, Hyukjin, Park, Jihyeong, Cho, Heeyeong

“…Direct inhibitors of glycogen synthase kinase 3β (GSK3β) have been investigated and reported for the past 20 years. In the search for novel scaffold…”
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Extraciliary roles of the ciliopathy protein JBTS17 in mitosis and neurogenesis by Hong, Hyowon, Joo, Kwangsic, Park, Sang Min, Seo, Jimyung, Kim, Min Hwan, Shin, EunBie, Cheong, Hae Il, Lee, Jeong Ho, Kim, Joon

“…Objective JBTS17 is a major gene mutated in ciliopathies such as Joubert syndrome and oral–facial–digital syndrome type VI. Most patients with loss of function…”
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A novel IRAK4/PIM1 inhibitor ameliorates rheumatoid arthritis and lymphoid malignancy by blocking the TLR/MYD88-mediated NF-κB pathway by Yoon, Sae-Bom, Hong, Hyowon, Lim, Hee-Jong, Choi, Ji Hye, Choi, Yoon Pyo, Seo, Seong Wook, Lee, Hyuk Woo, Chae, Chong Hak, Park, Woo-Kyu, Kim, Hyun Young, Jeong, Daeyoung, De, Tran Quang, Myung, Chang-Seon, Cho, Heeyeong

“…Interleukin-1 receptor-associated kinase 4 (IRAK4) is a pivotal enzyme in the Toll-like receptor (TLR)/MYD88 dependent signaling pathway, which is highly…”
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MeCP2 dysfunction prevents proper BMP signaling and neural progenitor expansion in brain organoid by Hong, Hyowon, Yoon, Sae‐Bom, Park, Jung Eun, Lee, Jung In, Kim, Hyun Young, Nam, Hye Jin, Cho, Heeyeong

“…Objectives Sporadic mutations in MeCP2 are a hallmark of Rett syndrome (RTT). Many RTT brain organoid models have exhibited pathogenic phenotypes such as…”
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Real-Time Monitoring of Molecules in Aqueous Solution via a Surface-Functionalized Ag-Anodic Aluminum Oxide Surface-Enhanced Raman Scattering Platform by Gwon, Geunyeol, Jung, Yujin, Hong, Hyowon, Cho, Heeyeong, Kim, Hyunwoo, Kim, Kyoung-Ho, Kim, Nam Hoon

“…Real-time monitoring of molecular species in aqueous solutions is crucial for diverse scientific applications, from biomedical diagnostics to environmental…”
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MK5 Regulates YAP Stability and Is a Molecular Target in YAP-Driven Cancers by Seo, Jimyung, Kim, Min Hwan, Hong, Hyowon, Cho, Hyunsoo, Park, Seongyeol, Kim, Sang Kyum, Kim, Joon

“…Transcriptional regulator YAP is activated in multiple human cancers and plays critical roles in tumor initiation, progression, metastasis, and drug…”
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Actin remodelling factors control ciliogenesis by regulating YAP/TAZ activity and vesicle trafficking by Kim, Jongshin, Jo, Haiin, Hong, Hyowon, Kim, Min Hwan, Kim, Jin Man, Lee, June-Koo, Heo, Won Do, Kim, Joon

“…Primary cilia exert a profound impact on cell signalling and cell cycle progression. Recently, actin cytoskeleton destabilization has been recognized as a…”
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Manufacturing Uniform Cerebral Organoids for Neurological Disease Modeling and Drug Evaluation by Hong, Hyowon, Jun, Yesl, Yoon, Sae-Bom, Park, Seoyoon, Lee, Jaemeun, Jang, Jeong Woon, Nam, Hye Jin, Cho, Heeyeong

“…Human cerebral organoids are promising tools for investigating brain development and the pathogenesis underlying neurological disorders. To use organoids for…”
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MCRS1 associates with cytoplasmic dynein and mediates pericentrosomal material recruitment by Lee, Si-Hyung, Lee, Mi-Sun, Choi, Tae-Ik, Hong, Hyowon, Seo, Jun-Young, Kim, Cheol-Hee, Kim, Joon

“…MCRS1 is involved in multiple cellular activities, including mitotic spindle assembly, mTOR signaling and tumorigenesis. Although MCRS1 has been reported to…”
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Extraciliary roles of the ciliopathy protein JBTS17 in mitosis and neurogenesis by Hong, Hyowon, Joo, Kwangsic, Park, Sang Min, Seo, Jimyung, Kim, Min Hwan, Shin, Eunbie, Cheong, Hae Il, Lee, Jeong Ho, Kim, Joon

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