Search Results - "Hong, Honghai"
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In silico identification of natural products from Traditional Chinese Medicine for cancer immunotherapy
Published in Scientific reports (08-02-2021)“…Advances in immunotherapy have revolutionized treatments in many types of cancer. Traditional Chinese Medicine (TCM), which has a long history of clinical…”
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Multiplexed Lab-on-a-Chip Bioassays for Testing Antibodies against SARS-CoV‑2 and Its Variants in Multiple Individuals
Published in Analytical chemistry (Washington) (08-02-2022)“…Neutralization assays that can measure neutralizing antibodies in serum are vital for large-scale serodiagnosis and vaccine evaluation. Here, we establish…”
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Circulating miR-10a as Predictor of Therapy Response in Rheumatoid Arthritis Patients Treated with Methotrexate
Published in Current pharmaceutical biotechnology (01-01-2018)“…Anti-inflammatory drugs and DMARDs, especially methotrexate, have dramatically improved the outlook of RA patient. However, in some patients the treatment…”
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The HMGB1-RAGE axis modulates the growth of autophagy-deficient hepatic tumors
Published in Cell death & disease (07-05-2020)“…Autophagy is an intracellular lysosomal degradative pathway important for tumor surveillance. Autophagy deficiency can lead to tumorigenesis. Autophagy is also…”
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Systems Pharmacology Approach to Investigate the Mechanism of Kai-Xin-San in Alzheimer's Disease
Published in Frontiers in pharmacology (03-04-2020)“…Alzheimer's disease (AD) is a complex neurodegenerative disease characterized by cognitive dysfunction. Kai-Xin-San (KXS) is a traditional Chinese medicine…”
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Elevated N6-Methyladenosine RNA Levels in Peripheral Blood Immune Cells: A Novel Predictive Biomarker and Therapeutic Target for Colorectal Cancer
Published in Frontiers in immunology (30-09-2021)“…Effective biomarkers for the diagnosis of colorectal cancer (CRC) are essential for improving prognosis. Imbalance in regulation of N6-methyladenosine (m A)…”
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Autophagy, Metabolism, and Alcohol-Related Liver Disease: Novel Modulators and Functions
Published in International journal of molecular sciences (11-10-2019)“…Alcohol-related liver disease (ALD) is caused by over-consumption of alcohol. ALD can develop a spectrum of pathological changes in the liver, including…”
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The dynamics of antibodies to SARS-CoV-2 in a case of SARS-CoV-2 infection
Published in International journal of infectious diseases (01-07-2020)Get full text
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Corrigendum: Systems pharmacology approach to investigate the mechanism of Kai-Xin-San in Alzheimer’s disease
Published in Frontiers in pharmacology (06-10-2023)“…[This corrects the article DOI: 10.3389/fphar.2020.00381.]…”
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Effects of SARS-CoV-2 infection on embryological outcomes in assisted reproductive technology during the Omicron epidemic
Published in Journal of ovarian research (22-11-2023)“…Abstract Background The influence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection on assisted reproductive technology (ART) has…”
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Aberrant Expression Profiles of lncRNAs and Their Associated Nearby Coding Genes in the Hippocampus of the SAMP8 Mouse Model with AD
Published in Molecular therapy. Nucleic acids (05-06-2020)“…The senescence-accelerated mouse prone 8 (SAMP8) mouse model is a useful model for investigating the fundamental mechanisms involved in the age-related…”
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Digital Hybridization Human Papillomavirus Assay with Attomolar Sensitivity without Amplification
Published in ACS nano (24-08-2021)“…Detection of nucleic acid without amplification can avoid problems associated with thermal cycling such as labor-intensiveness and aerosol pollution. Here we…”
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Rapid and visual detection of Mycoplasma genitalium using recombinase polymerase amplification combined with lateral flow strips
Published in Journal of microbiological methods (01-11-2024)“…Mycoplasma genitalium (MG) is an important sexually transmitted pathogen that can cause urethritis in males and pelvic inflammatory disease in females. Due to…”
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Hepatic senescence, the good and the bad
Published in World journal of gastroenterology : WJG (14-09-2019)“…Gradual alterations of cell's physiology and functions due to age or exposure to various stresses lead to the conversion of normal cells to senescent cells…”
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Identification of Circulating miR-125b as a Potential Biomarker of Alzheimer's Disease in APP/PS1 Transgenic Mouse
Published in Journal of Alzheimer's disease (01-01-2017)“…Alzheimer's disease (AD) is the most common form of dementia, characterized by progressive decline in cognitive abilities of the affected individuals…”
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Near-Infrared Radiation-Assisted Drug Delivery Nanoplatform to Realize Blood–Brain Barrier Crossing and Protection for Parkinsonian Therapy
Published in ACS applied materials & interfaces (11-08-2021)“…Mitochondrial dysfunction, which is directly involved in Parkinson’s disease (PD), is characterized by the production of reactive oxygen species (ROS) and…”
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Zebrafish: A Promising Model for Evaluating the Toxicity of Carbon Dot-Based Nanomaterials
Published in ACS applied materials & interfaces (28-10-2020)“…Carbon dots (CDs) exhibit a wide range of desirable properties including excellent photoluminescence, photostability, and water solubility, making them ideally…”
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FAM3L:Feature-Aware Multi-modal Metric Learning for Integrative Survival Analysis of Human Cancers
Published in IEEE transactions on medical imaging (01-09-2023)“…Survival analysis is to estimate the survival time for an individual or a group of patients, which is a valid solution for cancer treatments. Recent studies…”
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Recent Advances of Deep Learning for Computational Histopathology: Principles and Applications
Published in Cancers (25-02-2022)“…With the remarkable success of digital histopathology, we have witnessed a rapid expansion of the use of computational methods for the analysis of digital…”
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Adipose triglyceride lipase promotes the proliferation of colorectal cancer cells via enhancing the lipolytic pathway
Published in Journal of cellular and molecular medicine (01-04-2021)“…Abnormal lipid metabolism is the sign of tumour cells. Previous researches have revealed that the lipolytic pathway may contribute to the progression of…”
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