Search Results - "Hong, Gaobo"
-
1
An unexpected strategy to alleviate hypoxia limitation of photodynamic therapy by biotinylation of photosensitizers
Published in Nature communications (25-04-2022)“…The most common working mechanism of photodynamic therapy is based on high-toxicity singlet oxygen, which is called Type II photodynamic therapy. But it is…”
Get full text
Journal Article -
2
Self-assembly of amphiphilic peptides to construct activatable nanophotosensitizers for theranostic photodynamic therapy
Published in Chinese chemical letters (01-12-2021)“…A variety of nano-engineered photosensitizers have been developed for photodynamic therapy (PDT) of cancer diseases. However, traditional nano-engineering…”
Get full text
Journal Article -
3
Constructing a Local Hydrophobic Cage in Dye-Doped Fluorescent Silica Nanoparticles to Enhance the Photophysical Properties
Published in ACS central science (27-05-2020)“…Aggregation-caused quenching (ACQ) and poor photostability in aqueous media are two common problems for organic fluorescence dyes which cause a dramatic loss…”
Get full text
Journal Article -
4
Integration of TADF Photosensitizer as “Electron Pump” and BSA as “Electron Reservoir” for Boosting Type I Photodynamic Therapy
Published in Journal of the American Chemical Society (12-04-2023)“…Type I photosensitization provides an effective solution to the problem of unsatisfactory photodynamic therapeutic (PDT) effects caused by the tumor hypoxia…”
Get full text
Journal Article -
5
Self-assembly-integrated tumor targeting and electron transfer programming towards boosting tumor type I photodynamic therapy
Published in Chemical science (Cambridge) (17-07-2024)“…Type I photodynamic therapy (PDT) is attracting increasing interest as an effective solution to the poor prognosis of patients with hypoxic tumors. The…”
Get full text
Journal Article -
6
A Dual‐Nanozyme‐Catalyzed Cascade Reactor for Enhanced Photodynamic Oncotherapy against Tumor Hypoxia
Published in Advanced healthcare materials (01-11-2021)“…Tumor hypoxia is a typical characteristic of tumor microenvironment (TME), which seriously compromises the therapeutic effect of photodynamic therapy (PDT)…”
Get full text
Journal Article -
7
A dual-targeted theranostic photosensitizer based on a TADF fluorescein derivative
Published in Journal of controlled release (28-09-2019)“…Specific diagnosis and therapy of cancer is still a challenge in biomedical research. Photodynamic therapy (PDT) has emerged as a novel therapeutic modality…”
Get full text
Journal Article -
8
Jointly Depleting Glutathione Based on Self‐Assembled Nanomicelles for Enhancing Photodynamic Therapy
Published in Chembiochem : a European journal of chemical biology (15-08-2023)“…Photodynamic therapy (PDT) is one common ROS‐generating therapeutic method with high tumor selectivity and low side effects. But the GSH‐upregulation often…”
Get full text
Journal Article -
9
-
10
Liposome-Based Nanoencapsulation of a Mitochondria-Stapling Photosensitizer for Efficient Photodynamic Therapy
Published in ACS applied materials & interfaces (16-03-2022)“…Mitochondria-targeting photodynamic therapy (PDT) can block mitochondrial function and trigger the inherent proapoptotic cascade signal of mitochondria, which…”
Get full text
Journal Article -
11
Oxygen‐Insensitive Delayed Fluorescence Based on Singlet Manifold
Published in Advanced optical materials (01-03-2023)“…Delayed fluorescence molecules have important applications in time‐resolved luminescence imaging (including lifetime imaging) systems. However, existing…”
Get full text
Journal Article -
12
The Second Excited Triplet‐State Facilitates TADF and Triplet–Triplet Annihilation Photon Upconversion via a Thermally Activated Reverse Internal Conversion
Published in Advanced optical materials (01-03-2022)“…Recent years have seen a surge in organic emitters that exhibit thermally activated delayed fluorescence (TADF) behavior owing to their high exciton…”
Get full text
Journal Article -
13
Space-Arranged Intramolecular Modular Assembled Dyad as Superior-Performance “Superoxide Anion Engine” for Boosting Photodynamic Therapy
Published in ACS materials letters (15-05-2024)“…Tumor photodynamic therapy (PDT) has lauded the photosensitizers (PSs), yet their performance in most hypoxic tumors is still far from being satisfactory. In…”
Get full text
Journal Article -
14
Efficient Photodynamic Therapy Nanocarriers with Oxygen Saving and Smart Releasing–Translocating Properties
Published in ACS materials letters (03-07-2023)“…Photodynamic therapy (PDT) is becoming a promising therapeutic technology for treating cancer diseases. However, its efficiency is usually affected by the…”
Get full text
Journal Article -
15
Synthesis of Halogenated Curcumin Derivatives and Its Photodynamic Inactivation Effect on Vibrio parahaemolyticus
Published in Shípĭn kēxué (01-08-2024)“…In order to enhance the photodynamic inactivation (PDI) effect of curcumin, a novel class of halogenated curcumin derivatives X-cur (X = F, Cl or Br) was…”
Get full text
Magazine Article