Search Results - "Hong, Fangxin"

A comparison of meta-analysis methods for detecting differentially expressed genes in microarray experiments by Hong, Fangxin, Breitling, Rainer

“…Motivation: The proliferation of public data repositories creates a need for meta-analysis methods to efficiently evaluate, integrate and validate related…”
Get full text

RankProd 2.0: a refactored bioconductor package for detecting differentially expressed features in molecular profiling datasets by Del Carratore, Francesco, Jankevics, Andris, Eisinga, Rob, Heskes, Tom, Hong, Fangxin, Breitling, Rainer

“…The Rank Product (RP) is a statistical technique widely used to detect differentially expressed features in molecular profiling experiments such as…”
Get full text

Different Plant Hormones Regulate Similar Processes through Largely Nonoverlapping Transcriptional Responses by Nemhauser, Jennifer L., Hong, Fangxin, Chory, Joanne

“…Small-molecule hormones govern every aspect of the biology of plants. Many processes, such as growth, are regulated in similar ways by multiple hormones, and…”
Get full text

RankProd: a bioconductor package for detecting differentially expressed genes in meta-analysis by Hong, Fangxin, Breitling, Rainer, McEntee, Connor W., Wittner, Ben S., Nemhauser, Jennifer L., Chory, Joanne

“…While meta-analysis provides a powerful tool for analyzing microarray experiments by combining data from multiple studies, it presents unique computational…”
Get full text

Addition of Lenalidomide to R-CHOP Improves Outcomes in Newly Diagnosed Diffuse Large B-Cell Lymphoma in a Randomized Phase II US Intergroup Study ECOG-ACRIN E1412 by Nowakowski, Grzegorz S, Hong, Fangxin, Scott, David W, Macon, William R, King, Rebecca L, Habermann, Thomas M, Wagner-Johnston, Nina, Casulo, Carla, Wade, James L, Nagargoje, Gauri G, Reynolds, C M, Cohen, Jonathon B, Khan, Nadia, Amengual, Jennifer E, Richards, Kristy L, Little, R F, Leonard, John P, Friedberg, Jonathan W, Kostakoglu, Lale, Kahl, Brad S, Witzig, Thomas E

“…Lenalidomide combined with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) (R2CHOP) in untreated diffuse large B-cell…”
Get full text

Intrinsic Immunogenicity of Small Cell Lung Carcinoma Revealed by Its Cellular Plasticity by Mahadevan, Navin R, Knelson, Erik H, Wolff, Jacquelyn O, Vajdi, Amir, Saigí, Maria, Campisi, Marco, Hong, Deli, Thai, Tran C, Piel, Brandon, Han, Saemi, Reinhold, Bruce B, Duke-Cohan, Jonathan S, Poitras, Michael J, Taus, Luke J, Lizotte, Patrick H, Portell, Andrew, Quadros, Victor, Santucci, Alison D, Murayama, Takahiko, Cañadas, Israel, Kitajima, Shunsuke, Akitsu, Aoi, Fridrikh, Maya, Watanabe, Hideo, Reardon, Brendan, Gokhale, Prafulla C, Paweletz, Cloud P, Awad, Mark M, Van Allen, Eliezer M, Lako, Ana, Wang, Xi-Tao, Chen, Benjamin, Hong, Fangxin, Sholl, Lynette M, Tolstorukov, Michael Y, Pfaff, Kathleen, Jänne, Pasi A, Gjini, Evisa, Edwards, Robin, Rodig, Scott, Reinherz, Ellis L, Oser, Matthew G, Barbie, David A

“…Small cell lung carcinoma (SCLC) is highly mutated, yet durable response to immune checkpoint blockade (ICB) is rare. SCLC also exhibits cellular plasticity,…”
Get more information

Run-in Phase III Trial Design With Pharmacodynamics Predictive Biomarkers by FANGXIN HONG, SIMON, Richard

“…Developments in biotechnology have stimulated the use of predictive biomarkers to identify patients who are likely to benefit from a targeted therapy. Several…”
Get full text

Electronic Self-Report Assessment for Cancer and Self-Care Support: Results of a Multicenter Randomized Trial by BERRY, Donna L, FANGXIN HONG, AMTMANN, Dagmar, FORD, Rosemary, HALPENNY, Barbara, PARTRIDGE, Ann H, FANN, Jesse R, WOLPIN, Seth, LOBER, William B, BUSH, Nigel E, PARVATHANENI, Upendra, BACK, Anthony L

“…The purpose of this trial was to evaluate the effect of a Web-based, self-report assessment and educational intervention on symptom distress during cancer…”
Get full text

Subset of heat-shock transcription factors required for the early response of Arabidopsis to excess light by Jung, Hou-Sung, Crisp, Peter A., Estavillo, Gonzalo M., Cole, Benjamin, Hong, Fangxin, Mockler, Todd C., Pogson, Barry J., Chory, Joanne

“…Sunlight provides energy for photosynthesis and is essential for nearly all life on earth. However, too much or too little light or rapidly fluctuating light…”
Get full text

Signals from Chloroplasts Converge to Regulate Nuclear Gene Expression by Koussevitzky, Shai, Nott, Ajit, Mockler, Todd C, Hong, Fangxin, Sachetto-Martins, Gilberto, Surpin, Marci, Lim, Jason, Mittler, Ron, Chory, Joanne

“…Plastid-to-nucleus retrograde signaling coordinates nuclear gene expression with chloroplast function and is essential for the photoautotrophic life-style of…”
Get full text

Randomized Phase III Trial of ABVD Versus Stanford V With or Without Radiation Therapy in Locally Extensive and Advanced-Stage Hodgkin Lymphoma: An Intergroup Study Coordinated by the Eastern Cooperative Oncology Group (E2496) by GORDON, Leo I, FANGXIN HONG, ADVANI, Ranjana, KAHL, Brad S, FRIEDBERG, Jonathan W, BLUM, Kristie A, HABERMANN, Thomas M, TUSCANO, Joseph M, HOPPE, Richard T, HORNING, Sandra J, FISHER, Richard I, BARTLETT, Nancy L, CONNORS, Joseph M, GASCOYNE, Randy D, WAGNER, Henry, STIFF, Patrick J, CHESON, Bruce D, GOSPODAROWICZ, Mary

“…Although ABVD (doxorubicin, bleomycin, vinblastine, and dacarbazine) has been established as the standard of care in patients with advanced Hodgkin lymphoma,…”
Get full text

Exploring the impact of a decision support algorithm to improve clinicians' chemotherapy-induced peripheral neuropathy assessment and management practices: a two-phase, longitudinal study by Knoerl, Robert, Mazzola, Emanuele, Hong, Fangxin, Salehi, Elahe, McCleary, Nadine, Ligibel, Jennifer, Reyes, Kaitlen, Berry, Donna L

“…Chemotherapy-induced peripheral neuropathy (CIPN) negatively affects physical function and chemotherapy dosing, yet, clinicians infrequently document CIPN…”
Get full text

Tumor-associated macrophages predict inferior outcomes in classic Hodgkin lymphoma: a correlative study from the E2496 Intergroup trial by Tan, King L., Scott, David W., Hong, Fangxin, Kahl, Brad S., Fisher, Richard I., Bartlett, Nancy L., Advani, Ranjana H., Buckstein, Rena, Rimsza, Lisa M., Connors, Joseph M., Steidl, Christian, Gordon, Leo I., Horning, Sandra J., Gascoyne, Randy D.

“…Increased tumor-associated macrophages (TAMs) are reported to be associated with poor prognosis in classic Hodgkin lymphoma (CHL). We investigated the…”
Get full text

Rapid Synthesis of Auxin via a New Tryptophan-Dependent Pathway Is Required for Shade Avoidance in Plants by Tao, Yi, Ferrer, Jean-Luc, Ljung, Karin, Pojer, Florence, Hong, Fangxin, Long, Jeff A., Li, Lin, Moreno, Javier E., Bowman, Marianne E., Ivans, Lauren J., Cheng, Youfa, Lim, Jason, Zhao, Yunde, Ballaré, Carlos L., Sandberg, Göran, Noel, Joseph P., Chory, Joanne

“…Plants grown at high densities perceive a decrease in the red to far-red (R:FR) ratio of incoming light, resulting from absorption of red light by canopy…”
Get full text

Network discovery pipeline elucidates conserved time-of-day-specific cis-regulatory modules by Michael, Todd P, Mockler, Todd C, Breton, Ghislain, McEntee, Connor, Byer, Amanda, Trout, Jonathan D, Hazen, Samuel P, Shen, Rongkun, Priest, Henry D, Sullivan, Christopher M, Givan, Scott A, Yanovsky, Marcelo, Hong, Fangxin, Kay, Steve A, Chory, Joanne

“…Correct daily phasing of transcription confers an adaptive advantage to almost all organisms, including higher plants. In this study, we describe a…”
Get full text

Gene Expression–Based Model Using Formalin-Fixed Paraffin-Embedded Biopsies Predicts Overall Survival in Advanced-Stage Classical Hodgkin Lymphoma by SCOTT, David W, CHAN, Fong Chun, WOOLCOCK, Bruce W, FARINHA, Pedro, FISHER, Richard I, RIMSZA, Lisa M, BARTLETT, Nancy L, CHESON, Bruce D, SHEPHERD, Lois E, ADVANI, Ranjana H, CONNORS, Joseph M, KAHL, Brad S, FANGXIN HONG, GORDON, Leo I, HORNING, Sandra J, STEIDL, Christian, GASCOYNE, Randy D, ROGIC, Sanja, TAN, King L, MEISSNER, Barbara, BEN-NERIAH, Susana, BOYLE, Merrill, KRIDEL, Robert, TELENIUS, Adele

“…Our aim was to reliably identify patients with advanced-stage classical Hodgkin lymphoma (cHL) at increased risk of death by developing a robust predictor of…”
Get full text

STIMPY mediates cytokinin signaling during shoot meristem establishment in Arabidopsis seedlings by Skylar, Anna, Hong, Fangxin, Chory, Joanne, Weigel, Detlef, Wu, Xuelin

“…The establishment of the primary meristems through proliferation after germination is essential for plant post-embryonic development. Cytokinins have long been…”
Get full text

Plasma Epstein-Barr virus DNA predicts outcome in advanced Hodgkin lymphoma: correlative analysis from a large North American cooperative group trial by Kanakry, Jennifer A., Li, Hailun, Gellert, Lan L., Lemas, M. Victor, Hsieh, Wen-son, Hong, Fangxin, Tan, King L., Gascoyne, Randy D., Gordon, Leo I., Fisher, Richard I., Bartlett, Nancy L., Stiff, Patrick, Cheson, Bruce D., Advani, Ranjana, Miller, Thomas P., Kahl, Brad S., Horning, Sandra J., Ambinder, Richard F.

“…Epstein-Barr virus (EBV) is associated with Hodgkin lymphoma (HL) and can be detected by in situ hybridization (ISH) of viral nucleic acid (EBER) in tumor…”
Get full text

Molecular mechanisms of steroid hormone signaling in plants by Vert, Grégory, Nemhauser, Jennifer L, Geldner, Niko, Hong, Fangxin, Chory, Joanne

“…Brassinosteroids (BRs), the polyhydroxylated steroid hormones of plants, regulate the growth and differentiation of plants throughout their life cycle. Over…”
Get full text

The efficacy and tolerability of adriamycin, bleomycin, vinblastine, dacarbazine and Stanford V in older Hodgkin lymphoma patients: a comprehensive analysis from the North American intergroup trial E2496 by Evens, Andrew M., Hong, Fangxin, Gordon, Leo I., Fisher, Richard I., Bartlett, Nancy L., Connors, Joseph M., Gascoyne, Randy D., Wagner, Henry, Gospodarowicz, Mary, Cheson, Bruce D., Stiff, Patrick J., Advani, Ranjana, Miller, Thomas P., Hoppe, Richard T., Kahl, Brad S., Horning, Sandra J.

“…Summary There is a lack of contemporary prospective data examining the adriamycin, bleomycin, vinblastine, dacarbazine (ABVD) and Stanford V (SV; doxorubicin,…”
Get full text