Search Results - "Hong, A‐Reum"
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JNK suppresses melanogenesis by interfering with CREB-regulated transcription coactivator 3-dependent MITF expression
Published in Theranostics (01-01-2020)“…Melanogenesis is a critical self-defense mechanism against ultraviolet radiation (UVR)-induced skin damage and carcinogenesis; however, dysregulation of…”
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Journal Article -
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NEDD4L limits cAMP signaling through ubiquitination of CREB‐regulated transcription coactivator 3
Published in The FASEB journal (01-07-2018)“…The transcription factor cAMP‐responsive element‐binding protein (CREB) is involved in a variety of physiologic processes. Although its activity appears to be…”
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Journal Article -
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Therapeutic Potential of Rottlerin for Skin Hyperpigmentary Disorders by Inhibiting the Transcriptional Activity of CREB-Regulated Transcription Coactivators
Published in Journal of investigative dermatology (01-11-2019)“…Exposure to UVR stimulates the cAMP signaling pathway, which leads to melanin deposits in skin tissues. Although melanogenesis can be beneficial by protecting…”
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Journal Article