Search Results - "Honeyman, M. C"

Association between rotavirus infection and pancreatic islet autoimmunity in children at risk of developing type 1 diabetes by HONEYMAN, M. C, COULSON, B. S, STONE, N. L, GELLERT, S. A, GOLDWATER, P. N, STEELE, C. E, COUPER, J. J, TAIT, B. D, COLMAN, P. G, HARRISON, L. C

“…Association between rotavirus infection and pancreatic islet autoimmunity in children at risk of developing type 1 diabetes. M C Honeyman , B S Coulson , N L…”
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Congenital rubella, diabetes and HLA by Honeyman, M. C, Harrison, L. C

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Cow's milk and type 1 diabetes: the real debate is about mucosal immune function by HARRISON, L. C, HONEYMAN, M. C

“…Cow's milk and type 1 diabetes: the real debate is about mucosal immune function. L C Harrison and M C Honeyman The Walter and Eliza Hall Institute of Medical…”
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T-cell epitopes in type 1 diabetes autoantigen tyrosine phosphatase IA-2: potential for mimicry with rotavirus and other environmental agents by Honeyman, M C, Stone, N L, Harrison, L C

“…The tyrosine phosphatase IA-2 is a molecular target of pancreatic islet autoimmunity in type 1 diabetes. T-cell epitope peptides in autoantigens have potential…”
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Neural network-based prediction of candidate T-cell epitopes by Honeyman, Margo C, Brusic, Vladimir, Stone, Natalie L, Harrison, Leonard C

“…Activation of T cells requires recognition by T-cell receptors of specific peptides bound to major histocompatibility complex (MHC) molecules on the surface of…”
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Impaired Yield, Phenotype, and Function of Monocyte-Derived Dendritic Cells in Humans at Risk for Insulin-Dependent Diabetes by Takahashi, Kazuma, Honeyman, Margo C, Harrison, Leonard C

“…Dendritic cells (DC) present Ag to naive T cells and are therefore pivotal in shaping immune responses. DC may either immunize or tolerize T cells. Humans with…”
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Inverse relation between humoral and cellular immunity to glutamic acid decarboxylase in subjects at risk of insulin-dependent diabetes by Harrison, L C, Honeyman, M C, DeAizpurua, H J, Schmidli, R S, Colman, P G, Tait, B D, Cram, D S

“…Glutamic acid decarboxylase (GAD) in pancreatic beta cells is an autoantigen in insulin-dependent diabetes (IDD). We measured immunity to GAD in 31…”
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Glutamic acid decarboxylase 67-reactive T cells : a marker of insulin-dependent diabetes by HONEYMAN, M. C, CRAM, D. S, HARRISON, L. C

“…Glutamic acid decarboxylase (GAD) has been shown to be a target of autoantibodies in insulin-dependent diabetes (IDD). Two forms of GAD, with molecular weights…”
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High T Cell Responses to the Glutamic Acid Decarboxylase (GAD) Isoform 67 Reflect a Hyperimmune State that Precedes the Onset of Insulin-Dependent Diabetes by Honeyman, Margo C., Stone, Natalie, de Aizpurua, Henry, Rowley, Merrill J., Harrison, Leonard C.

“…Pancreatic islet β-cell destruction leading to insulin-dependent diabetes mellitus (IDDM) is an autoimmune T cell-mediated process. Peripheral blood T cells,…”
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Analysis of families at risk for insulin-dependent diabetes mellitus reveals that HLA antigens influence progression to clinical disease by Honeyman, M C, Harrison, L C, Drummond, B, Colman, P G, Tait, B D

“…Individuals at risk for insulin-dependent diabetes mellitus (IDDM), with an affected first-degree relative, can be identified by the presence of islet cell…”
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A sensitive method for detecting proliferation of rare autoantigen-specific human T cells by Mannering, Stuart I, Morris, Jessica S, Jensen, Kent P, Purcell, Anthony W, Honeyman, Margo C, van Endert, Peter M, Harrison, Leonard C

“…The ability to measure proliferation of rare antigen-specific T cells among many bystanders is critical for the evaluation of cellular immune function in…”
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The Melbourne Pre‐Diabetes Study: prediction of type 1 diabetes mellitus using antibody and metabolic testing by Colman, Peter G, McNair, Peter, Margetts, Heather, Schmidli, Robert S, Tait, Brian D, Honeyman, Margo C, Harrison, Leonard C, Werther, George A, Alford, Frank P, Ward, Glenn M

“…Objectives: To determine the utility of various autoantibodies in predicting progression to clinical diabetes in first‐degree relatives of patients with type 1…”
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Islet-reactive T cells are a marker of preclinical insulin-dependent diabetes by HARRISON, L. C, CHU, S. X, DEAIZPURUA, H.J, GRAHAML, M, HONEYMAN, M. C, COLMAN, P. G

“…The destruction of pancreatic islet beta cells in insulin-dependent diabetes mellitus (IDDM) is thought to be T cell mediated. To directly identify…”
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Transcription factor jun-B is target of autoreactive T-cells in IDDM by Honeyman, M. C., Cram, D. S., Harrison, L. C.

“…Transcription factor jun-B is target of autoreactive T-cells in IDDM. M C Honeyman , D S Cram and L C Harrison Burnet Clinical Research Unit, Walter and Eliza…”
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A Novel Subtype of Type 1 Diabetes Mellitus by Honeyman, Margo C, Coulson, Barbara S, Harrison, Leonard C, Tanaka, Shoichiro, Kobayashi, Tetsuro, Momotsu, Takeshi, Imagawa, Akihisa, Miyagawa, Jun-ichiro, Hanafusa, Toshiaki

“…To the Editor: Imagawa and colleagues (Feb. 3 issue) 1 provide evidence that an acute insult to the exocrine pancreas, possibly caused by a virus, may trigger…”
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Similar peptides from two beta cell autoantigens, proinsulin and glutamic acid decarboxylase, stimulate T cells of individuals at risk for insulin-dependent diabetes by Rudy, G, Stone, N, Harrison, L C, Colman, P G, McNair, P, Brusic, V, French, M B, Honeyman, M C, Tait, B, Lew, A M

“…Insulin (1) and glutamic acid decarboxylase (GAD) (2) are both autoantigens in insulin-dependent diabetes mellitus (IDDM), but no molecular mechanism has been…”
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Growth of Rotaviruses in Primary Pancreatic Cells by Coulson, Barbara S, Witterick, Paul D, Tan, Yan, Hewish, Marilyn J, Mountford, Joanne N, Harrison, Leonard C, Honeyman, Margo C

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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A peptide-binding motif for I-A(g7), the class II major histocompatibility complex (MHC) molecule of NOD and Biozzi AB/H mice by Harrison, L C, Honeyman, M C, Trembleau, S, Gregori, S, Gallazzi, F, Augstein, P, Brusic, V, Hammer, J, Adorini, L

“…The class II major histocompatibility complex molecule I-A(g7) is strongly linked to the development of spontaneous insulin-dependent diabetes mellitus (IDDM)…”
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HLA genes associated with autoimmunity and progression to disease in type 1 diabetes by Tait, B.D., Colman, P.G., Morahan, G., Marchinovska, L., Dore, E., Gellert, S., Honeyman, M.C., Stephen, K., Loth, A.

“…: Insulin dependent diabetes mellitus (type I DM) is caused by an autoimmune process which culminates in destruction of pancreatic beta cells with resultant…”
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Cytotoxic T Cells to an Epitope in the Islet Autoantigen IA-2 Are Not Disease-Specific by Takahashi, Kazuma, Honeyman, Margo C., Harrison, Leonard C.

“…Cytotoxic CD8 T lymphocytes (CTL) are effectors of pancreatic islet β-cell destruction in type 1 diabetes but, with the exception of a single report, CTL to…”
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