Search Results - "Honetschlägerová, Zuzana"

Impaired renal autoregulation and pressure-natriuresis: any role in the development of heart failure in normotensive and angiotensin II-dependent hypertensive rats? by Honetschlägerová, Zuzana, Sadowski, Janusz, Kompanowska-Jezierska, Elzbieta, Maxová, Hana, Táborský, Miloš, Kujal, Petr, Červenka, Luděk

“…The aim of the present study was to assess the autoregulatory capacity of renal blood flow (RBF) and of the pressure-natriuresis characteristics in the early…”
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The treatment with sGC stimulator improves survival of hypertensive rats in response to volume-overload induced by aorto-caval fistula by Gawrys, Olga, Husková, Zuzana, Škaroupková, Petra, Honetschlägerová, Zuzana, Vaňourková, Zdeňka, Kikerlová, Soňa, Melenovský, Vojtěch, Bačová, Barbara Szeiffová, Sykora, Matúš, Táborský, Miloš, Červenka, Luděk

“…Heart failure (HF) has been declared as global pandemic and current therapies are still ineffective, especially in patients that develop concurrent…”
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Renal denervation improves cardiac function independently of afterload and restores myocardial norepinephrine levels in a rodent heart failure model by Miklovič, Matúš, Gawryś, Olga, Honetschlägerová, Zuzana, Kala, Petr, Husková, Zuzana, Kikerlová, Soňa, Vaňourková, Zdeňka, Jíchová, Šárka, Kvasilová, Alena, Kitamoto, Misuzu, Maxová, Hana, Puertas-Frias, Guillermo, Mráček, Tomáš, Sedmera, David, Melenovský, Vojtěch

“…Renal nerves play a critical role in cardiorenal interactions. Renal denervation (RDN) improved survival in some experimental heart failure (HF) models. It is…”
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Effects of Renal Denervation on the Enhanced Renal Vascular Responsiveness to Angiotensin II in High-Output Heart Failure: Angiotensin II Receptor Binding Assessment and Functional Studies in Ren-2 Transgenic Hypertensive Rats by Honetschlägerová, Zuzana, Hejnová, Lucie, Novotný, Jiří, Marek, Aleš, Červenka, Luděk

“…Detailed mechanism(s) of the beneficial effects of renal denervation (RDN) on the course of heart failure (HF) remain unclear. The study aimed to evaluate…”
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Renal mechanisms contributing to the antihypertensive action of soluble epoxide hydrolase inhibition in Ren‐2 transgenic rats with inducible hypertension by Honetschlägerová, Zuzana, Husková, Zuzana, Vaňourková, Zdeňka, Sporková, Alexandra, Kramer, Herbert J., Hwang, Sung Hee, Tsai, Hsing‐Ju, Hammock, Bruce D., Imig, John D., Červenka, Luděk, Kopkan, Libor

“…Non‐technical summary Arachidonic acid metabolites called epoxyeicosatrienoic acids (EETs) influence vascular tone and renal tubular sodium and water transport…”
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Inhibition of soluble epoxide hydrolase improves the impaired pressure–natriuresis relationship and attenuates the development of hypertension and hypertension-associated end-organ damage in Cyp1a1-Ren-2 transgenic rats by Honetschlägerová, Zuzana, Sporková, Alexandra, Kopkan, Libor, Husková, Zuzana, Hwang, Sung H, Hammock, Bruce D, Imig, John D, Kramer, Herbert J, Kujal, Petr, Vernerová, Zdenka, Chábová, Věra Č, Tesař, Vladimír, Červenka, Luděk

“…OBJECTIVEIn the present study, we compared the effects of treatment with the novel soluble epoxide hydrolase (sEH) inhibitor (c-AUCB) with those of the AT1…”
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Effects of renal sympathetic denervation on the course of congestive heart failure combined with chronic kidney disease: Insight from studies with fawn-hooded hypertensive rats with volume overload induced using aorto-caval fistula by Honetschlagerová, Zuzana, Škaroupková, Petra, Kikerlová, Soňa, Husková, Zuzana, Maxová, Hana, Melenovský, Vojtěch, Kompanowska-Jezierska, Elzbieta, Sadowski, Janusz, Gawrys, Olga, Kujal, Petr, Červenka, Luděk, Čertíková Chábová, Věra

“…Background: The coincidence of congestive heart failure (CHF) and chronic kidney disease (CKD) results in poor survival rate. The aim of the study was to…”
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Renal Sympathetic Denervation Attenuates Congestive Heart Failure in Angiotensin II-Dependent Hypertension: Studies with Ren-2 Transgenic Hypertensive Rats with Aortocaval Fistula by Honetschlagerová, Zuzana, Gawrys, Olga, Jíchová, Šárka, Škaroupková, Petra, Kikerlová, Soňa, Vaňourková, Zdeňka, Husková, Zuzana, Melenovský, Vojtěch, Kompanowska-Jezierska, Elzbieta, Sadowski, Janusz, Kolář, František, Novotný, Jiří, Hejnová, Lucie, Kujal, Petr, Červenka, Luděk

“…Objective: We examined if renal denervation (RDN) attenuates the progression of aortocaval fistula (ACF)-induced heart failure or improves renal hemodynamics…”
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Effective Antihypertensive Treatment with Epoxyeicosatrienoic Acid Analog (EET‐A) and 20‐HETE Antagonist (AAA) of Spontaneously Hypertensive Rats (SHR) by Gawrys, Olga, Walkowska, Agnieszka, Kompanowska-Jezierska, Elzbieta, Husková, Zuzana, Honetschlägerová, Zuzana, Falck, John, Imig, John, Červenka, Luděk

“…Abstract only Introduction Despite decades of research the death toll of hypertension and associated disorders increases significantly each year. This impose…”
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Renal sympathetic denervation improves pressure-natriuresis relationship in cardiorenal syndrome: insight from studies with Ren-2 transgenic hypertensive rats with volume overload induced using aorto-caval fistula by Honetschlägerová, Zuzana, Husková, Zuzana, Kikerlová, Soňa, Sadowski, Janusz, Kompanowska-Jezierska, Elzbieta, Táborský, Miloš, Vaňourková, Zdenka, Kujal, Petr, Červenka, Luděk

“…The aim was to evaluate the effects of renal denervation (RDN) on autoregulation of renal hemodynamics and the pressure-natriuresis relationship in Ren-2…”
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Combined treatment with epoxyeicosatrienoic acid analog and 20-hydroxyeicosatetraenoic acid antagonist provides substantial hypotensive effect in spontaneously hypertensive rats by Gawrys, Olga, Husková, Zuzana, Baranowska, Iwona, Walkowska, Agnieszka, Sadowski, Janusz, Kikerlová, Soňa, Vaňourková, Zdeňka, Honetschlägerová, Zuzana, Škaroupková, Petra, Červenka, Luděk, Falck, John R., Imig, John D., Kompanowska-Jezierska, Elzbieta

“…OBJECTIVES:The global morbidity and mortality related to hypertension and associated disorders increases continuously and novel therapeutic strategies are…”
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Renal sympathetic denervation attenuates congestive heart failure in angiotensin II‐dependent hypertension: studies with Ren‐2 transgenic hypertensive rats with aorto‐caval fistula by Honetschlagerova, Zuzana, Melenovsky, Vojtech

“…Abstract only Objective We hypothesized that renal denervation (RDN) attenuates the progression of aorto‐caval fistula (ACF)‐induced heart failure (HF) and the…”
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Abstract P2034: Effects of Renal Denervation on the Course of Heart Failure and Occurrence of Renal Dysfunction in Ren-2 Transgenic Hypertensive Rats With Aorto-Caval Fistula by Honetschlagerova, Zuzana, Cervenka, Ludek

“…Abstract only Objective: We hypothesized that renal denervation (RDN) attenuates the progression of aorto-caval fistula (ACF)-induced heart failure (HF) and…”
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Antihypertensive and renoprotective actions of soluble epoxide hydrolase inhibition in ANG II-dependent malignant hypertension are abolished by pretreatment with L-NAME by Honetschlägerová, Zuzana, Kitada, Kento, Husková, Zuzana, Sporková, Alexandra, Kopkan, Libor, Bürgelová, Marcela, Varcabová, Šárka, Nishiyama, Akira, Hwang, Sung Hee, Hammock, Bruce D, Imig, John D, Kramer, Herbert J, Kujal, Petr, Vernerová, Zdenka, Červenka, Luděk

“…OBJECTIVE:The present study was performed to investigate in a model of malignant hypertension if the antihypertensive actions of soluble epoxide hydrolase…”
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S-12-5: IMPAIRMENT OF RENAL BLOOD FLOW AUTOREGULATION AND PRESSURE-NATRIURESIS: ROLE IN THE DEVELOPMENT OF HEART FAILURE IN REN-2 TRANSGENIC HYPERTENSIVE RATS by Honetschlagerova, Zuzana, Sadowski, Janusz, Jezierska, Elzbieta Kompanowska, Cervenka, Ludek

“…Objective: The prognosis of patients with heart failure (HF), particularly those who were hypertensive before the onset of HF, remains poor and new therapeutic…”
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PS-B03-2: SGC STIMULATOR, BAY41 8543, FOR THE TREATMENT OF HEART FAILURE WITH REDUCED EJECTION FRACTION AND CARDIORENAL SYNDROME by Gawrys, Olga, Skaroupkova, Petra, Huskova, Zuzana, Honetschlagerova, Zuzana, Vanourkova, Zdenka, Kikerlova, Sona, Melenovsky, Vojtech, Cervenka, Ludek

“…Objective: Heart failure with reduced ejection fraction (HFrEF) imposes a significant health and socioeconomic burden. The life expectancy and prognosis are…”
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Abstract 9961: Combination Therapy with Selective Endothelin Type A Receptor Blockade and Angiotensin-converting Enzyme Blockade Improves Survival of Congestive Heart Failure Similarly to Both Monotherapies: Study in Ren-2 Transgenic Hypertensive Rats with Aorto-Caval Fistula by Kala, Petr, Miklovic, Matus, Honetschlagerova, Zuzana, Skaroupkova, Petra, Huskova, Zuzana, Melenovsky, Vojtech, Veselka, Josef, Cervenka, Ludek

“…IntroductionNew therapeutic strategies for congestive heart failure (CHF) are needed, and the current knowledge, including our previous studies, suggests that…”
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Soluble Epoxide Hydrolase Inhibition Exhibits Antihypertensive Actions Independently of Nitric Oxide in Mice with Renovascular Hypertension by Kopkan, Libor, Husková, Zuzana, Sporková, Alexandra, Varcabová, Šárka, Honetschlägerová, Zuzana, Hwang, Sung Hee, Tsai, Hsing-Ju, Hammock, Bruce D., Imig, John D., Kramer, Herbert J., Bürgelová, Marcela, Vojtíšková, Alžběta, Kujal, Petr, Vernerová, Zdenka, Červenka, Luděk

“…Objective: The present study was performed to examine whether the blood pressure (BP)-lowering effects of soluble epoxide hydrolase (sEH) inhibition in…”
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Abstract 14613: Preclinical Animal Model of Doxorubicin-induced Left Ventricular Dysfunction: Echocardiography and Pressure-volume Analysis by Kala, Petr, Honetschlagerova, Zuzana, Huskova, Zuzana, Vanourkova, Zdenka, Škaroupková, Petra, Melenovsky, Vojtech, Veselka, Josef, Cervenka, Ludek

“…IntroductionThere is a need to implement a preclinical model in addition to the well established ischemic or volume-overload models that would mimic the…”
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Abstract Tu057: Renal denervation enhances right ventricular function, reduces myocardial damage, and restores myocardial sympathetic signaling in rats with heart failure induced by volume overload by Miklovic, Matus, Gawrys, Olga, Honetschlagerova, Zuzana, Kala, Petr, Huskova, Zuzana, Kikerlova, Sona, Vanourkova, Zdenka, Maxova, Hana, Puertas-Frias, Guillermo, Kitamoto, Misuzu, Adamova, Marketa, Jichova, Sarka, Kvasilova, Alena, Mracek, Tomas, Sedmera, David, Melenovsky, Vojtech

“…Abstract only Introduction: Heart failure (HF) is associated with chronically increased sympathetic nervous activity with depleted norepinephrine (NE) in the…”
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