Search Results - "Honegger, Jonathan"

Defer no more: advances in the treatment and prevention of chronic hepatitis C virus infection in children by Honegger, Jonathan R., Gowda, Charitha

“…Direct-acting antiviral (DAA) regimens targeting hepatitis C virus (HCV) are now approved for young children. This review examines recent DAA experience in…”
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Hepatitis C virus in pregnancy by Prasad, Mona R, Honegger, Jonathan R

“…Despite recent advances in the pathogenesis, treatment, and public health response to hepatitis C virus (HCV), HCV as it specifically relates to pregnancy has…”
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Nucleic Acid Testing for Diagnosis of Perinatally Acquired Hepatitis C Virus Infection in Early Infancy by Gowda, Charitha, Smith, Stephanie, Crim, Linda, Moyer, Katherine, Sánchez, Pablo J, Honegger, Jonathan R

“…Abstract Background Most US children with perinatal hepatitis C virus (HCV) exposure fail to receive the recommended anti-HCV antibody test at age ≥18 months…”
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T-Cell Immunity against the Hepatitis C Virus: A Persistent Research Priority in an Era of Highly Effective Therapy by Smith, Stephanie, Honegger, Jonathan R, Walker, Christopher

“…Approximately 70% of acute hepatitis C virus (HCV) infections become chronic, indicating that the virus is exceptionally well adapted to persist in humans with…”
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Will there be a vaccine to prevent HCV infection? by Honegger, Jonathan R, Zhou, Yan, Walker, Christopher M

“…Prevention of hepatitis C virus (HCV) infection by vaccination has been a priority since discovery of the virus and the need has not diminished over the past…”
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Ledipasvir‐Sofosbuvir for 12 Weeks in Children 3 to <6 Years Old With Chronic Hepatitis C by Schwarz, Kathleen B., Rosenthal, Philip, Murray, Karen F., Honegger, Jonathan R., Hardikar, Winita, Hague, Rosie, Mittal, Naveen, Massetto, Benedetta, Brainard, Diana M., Hsueh, Chia‐Hsiang, Shao, Jiang, Parhy, Bandita, Narkewicz, Michael R., Rao, Girish S., Whitworth, Suzanne, Bansal, Sanjay, Balistreri, William F.

“…For children under 12 years of age who have chronic hepatitis C virus (HCV) infection, there are currently no approved treatments with direct‐acting antiviral…”
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New prospects for the treatment and prevention of hepatitis C in children by Ohmer, Samantha, Honegger, Jonathan

“…Combined pegylated interferon-α and ribavirin remains the standard therapy for pediatric hepatitis C virus (HCV) infections in 2016, but direct-acting…”
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Severe SARS-CoV-2 disease in the context of a NF-κB2 loss-of-function pathogenic variant by Abraham, Roshini S., Marshall, Joanna M., Kuehn, Hye Sun, Rueda, Cesar M., Gibbs, Amber, Guider, Will, Stewart, Claire, Rosenzweig, Sergio D., Wang, Huanyu, Jean, Sophonie, Peeples, Mark, King, Tiffany, Hunt, W. Garrett, Honegger, Jonathan R., Ramilo, Octavio, Mustillo, Peter J., Mejias, Asuncion, Ardura, Monica I., Shimamura, Masako

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus that emerged recently and has created a global pandemic. Symptomatic…”
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CD4+ T cell restoration and control of hepatitis C virus replication after childbirth by Coss, Samantha L, Torres-Cornejo, Almudena, Prasad, Mona R, Moore-Clingenpeel, Melissa, Grakoui, Arash, Lauer, Georg M, Walker, Christopher M, Honegger, Jonathan R

“…Chronic hepatitis C virus (HCV) infection is characterized by persistent high-level viremia and defective cellular immunity, including a lack of functional…”
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Where to Next? Research Directions after the First Hepatitis C Vaccine Efficacy Trial by Phelps, Christopher C, Walker, Christopher M, Honegger, Jonathan R

“…Thirty years after its discovery, the hepatitis C virus (HCV) remains a leading cause of liver disease worldwide. Given that many countries continue to…”
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Enhanced identification of maternal hepatitis C virus infection using existing public health surveillance systems by Gowda, Charitha, Kennedy, Samuel, Glover, Catherine, Prasad, Mona R., Wang, Ling, Honegger, Jonathan R.

“…Background Hepatitis C virus (HCV) infection is under‐recognized among US adults and children. Prenatal HCV screening may help close the diagnosis gap among…”
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Loss of immune escape mutations during persistent HCV infection in pregnancy enhances replication of vertically transmitted viruses by Honegger, Jonathan R, Kim, Seungtaek, Price, Aryn A, Kohout, Jennifer A, McKnight, Kevin L, Prasad, Mona R, Lemon, Stanley M, Grakoui, Arash, Walker, Christopher M

“…Here, Honegger et al . study two HCV-infected women through two consecutive pregnancies and chronicle T cell escape mutations in viral proteins that revert…”
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Clinical and Radiologic Manifestations of Bone Infection in Children with Cat Scratch Disease by Erdem, Guliz, Watson, Joshua R., Hunt, W. Garrett, Young, Cody, Tomatis Souverbielle, Cristina, Honegger, Jonathan R., Cassady, Kevin A., Ilgenfritz, Megan, Napolitano, Stephanie, Koranyi, Katalin

“…We identified 13 patients with cat scratch (Bartonella henselae) bone infection among those admitted to a large tertiary care children's hospital over a…”
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Prolonged activation of innate antiviral gene signature after childbirth is determined by IFNL3 genotype by Price, Aryn A., Tedesco, Dana, Prasad, Mona R., Workowski, Kimberly A., Walker, Christopher M., Suthar, Mehul S., Honegger, Jonathan R., Grakoui, Arash

“…Maternal innate and adaptive immune responses are modulated during pregnancy to concurrently defend against infection and tolerate the semiallogeneic fetus…”
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Influence of IFNL3 and HLA-DPB1 genotype on postpartum control of hepatitis C virus replication and T-cell recovery by Honegger, Jonathan R., Tedesco, Dana, Kohout, Jennifer A., Prasad, Mona R., Price, Aryn A., Lindquist, Tera, Ohmer, Samantha, Moore-Clingenpeel, Melissa, Grakoui, Arash, Walker, Christopher M.

“…Chronic hepatitis C virus (HCV) infection is characterized by exhaustion of virus-specific T-cells and stable viremia. Pregnancy is an exception. Viremia…”
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T cell responses and clinical symptoms among infants with congenital cytomegalovirus infection by Medoro, Alexandra K, Dhital, Ravi, Sánchez, Pablo J, Flint, Kaitlyn, Graber, Brianna, Pifer, Traci, Crisan, Rachelle, Ray, William C, Phelps, Christopher C, Honegger, Jonathan R, Peng, Jing, Findlen, Ursula, Malhotra, Prashant, Adunka, Oliver, Shimamura, Masako

“…BACKGROUNDCongenital cytomegalovirus (cCMV) infection can cause developmental impairment and sensorineural hearing loss (SNHL). To determine the relationship…”
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Presentation and outcome of histoplasmosis in pediatric inflammatory bowel disease patients treated with antitumor necrosis factor alpha therapy: A case series by Dotson, Jennifer L., Crandall, Wallace, Mousa, Hayat, Honegger, Jonathan R., Denson, Lee, Samson, Charles, Cunningham, Dennis, Balint, Jane, Dienhart, Molly, Jaggi, Preeti, Carvalho, Ryan

“…Background: Antitumor necrosis factor alpha (aTNF) therapies are commonly used in the treatment of pediatric inflammatory bowel disease (IBD). However,…”
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Defer no more: Advances in the treatment and prevention of chronic HCV infection in children by Honegger, Jonathan R., Gowda, Charitha

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Defer no more: advances in the treatment and prevention of chronic hepatitis C virus infection in children by Honegger, Jonathan R., Gowda, Charitha

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HCV-specific T-cell responses during acute Hepatitis C Virus infection in pregnancy by Honegger, Jonathan, Prasad, Mona, Colombo, David, Bowen, David, Walker, Christopher

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