Search Results - "Honap, Sailish"

Effectiveness and Safety of Ustekinumab in Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis by Honap, Sailish, Meade, Susanna, Ibraheim, Hajir, Irving, Peter M., Jones, Michael P., Samaan, Mark A.

“…Introduction Ustekinumab, an interleukin-12 and interleukin-23 antagonist, is licensed for the treatment of Crohn’s disease (CD) and ulcerative colitis (UC)…”
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Real-world Effectiveness of Tofacitinib for Moderate to Severe Ulcerative Colitis: A Multicentre UK Experience by Honap, Sailish, Chee, Desmond, Chapman, Thomas P, Patel, Mehul, Kent, Alexandra J, Ray, Shuvra, Sharma, Esha, Kennedy, James, Cripps, Sarah, Walsh, Alissa, Goodhand, James R, Ahmad, Tariq, Satsangi, Jack, Irving, Peter M, Kennedy, Nicholas A

“…Abstract Background Tofacitinib is a partially selective Janus kinase inhibitor approved for the treatment of refractory moderate to severe ulcerative colitis…”
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Biomarkers in inflammatory bowel disease: a practical guide by Clough, Jennie, Colwill, Michael, Poullis, Andrew, Pollok, Richard, Patel, Kamal, Honap, Sailish

“…Inflammatory bowel disease (IBD), comprising ulcerative colitis (UC) and Crohn's disease (CD), is a costly condition in terms of morbidity and healthcare…”
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Can We Predict the Toxicity and Response to Thiopurines in Inflammatory Bowel Diseases? by Luber, Raphael P, Honap, Sailish, Cunningham, Georgina, Irving, Peter M

“…Thiopurines are a cheap, effective treatment option in the management of inflammatory bowel disease (IBD). However, with the growing choice of targeted…”
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Depression, anxiety, and stress among inflammatory bowel disease patients during COVID‐19: A UK cohort study by Luber, Raphael P, Duff, Alexa, Pavlidis, Polychronis, Honap, Sailish, Meade, Susanna, Ray, Shuvra, Anderson, Simon H, Mawdsley, Joel, Samaan, Mark A, Irving, Peter M

“…Background and Aim Patients with chronic diseases are believed to be at increased risk of mental health conditions during the COVID‐19 pandemic. We aimed to…”
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Effectiveness of vedolizumab dose intensification to achieve inflammatory bowel disease control in cases of suboptimal response by Samaan, Mark A, Birdi, Siddharth, Morales, Maria Sierra, Honap, Sailish, Tamilarasan, Aravind Gokul, Cunningham, Georgina, Koumoutsos, Ioannis, Ray, Shuvra, Mawdsley, Joel, Anderson, Simon H C, Sanderson, Jeremy, Irving, Peter M

“…BackgroundDespite the proven efficacy of vedolizumab (VDZ) for ulcerative colitis (UC) and Crohn’s disease (CD), suboptimal response is commonly encountered…”
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Ulcerative colitis by Le Berre, Catherine, Honap, Sailish, Peyrin-Biroulet, Laurent

“…Ulcerative colitis is a lifelong inflammatory disease affecting the rectum and colon to a variable extent. In 2023, the prevalence of ulcerative colitis was…”
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Amoebic colitis masquerading as inflammatory bowel disease for a decade by Honap, Sailish, Anderson, Simon

“…Treatment was escalated to combination azathioprine and weekly adalimumab, and while there was some symptomatic benefit, reassessment colonoscopy in 2018…”
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Target Trial Emulation: Improving the Quality of Observational Studies in Inflammatory Bowel Disease Using the Principles of Randomized Trials by Honap, Sailish, Danese, Silvio, Peyrin-Biroulet, Laurent

“…The past decade has seen a substantial increase in the number of randomized controlled trials (RCTs) conducted in inflammatory bowel disease (IBD). Randomized…”
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Navigating the complexities of drug development for inflammatory bowel disease by Honap, Sailish, Jairath, Vipul, Danese, Silvio, Peyrin-Biroulet, Laurent

“…Inflammatory bowel disease (IBD) — consisting of ulcerative colitis and Crohn’s disease — is a complex, heterogeneous, immune-mediated inflammatory condition…”
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Amoebic colitis masquerading as inflammatory bowel disease for a decade by Honap, Sailish, Anderson, Simon

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Epidemiology of Inflammatory Bowel Disease across the Ages in the Era of Advanced Therapies by Caron, Bénédicte, Honap, Sailish, Peyrin-Biroulet, Laurent

“…The incidence of inflammatory bowel diseases [IBD] has risen over the past decade to become a global issue. The objectives of this review were to describe the…”
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Disease prevention trials in IBD: feasibility to future outlook by Honap, Sailish, Agrinier, Nelly, Danese, Silvio, Peyrin-Biroulet, Laurent

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Are All Janus Kinase Inhibitors for Inflammatory Bowel Disease the Same? by Honap, Sailish, Danese, Silvio, Peyrin-Biroulet, Laurent

“…Ulcerative colitis and Crohn's disease are chronic, progressive inflammatory bowel diseases (IBDs) and are without a known cure. Janus kinase (JAK) is a family…”
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5-ASAs in Crohn’s Disease: Time to Stop the Salicylate? by Honap, Sailish, Sharma, Esha, Samaan, Mark A.

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Editorial: is tofacitinib another rescue option for acute severe ulcerative colitis? by Honap, Sailish, Pavlidis, Polychronis, Irving, Peter M.

“…LINKED CONTENT This article is linked to Uzzan et al paper. To view this article, visit https://doi.org/10.1111/apt.16463…”
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Personalized (N-of-1) Clinical Trials for Inflammatory Bowel Disease: Opportunities and Challenges by Honap, Sailish, Zou, Guangyong, Danese, Silvio, Peyrin-Biroulet, Laurent, Jairath, Vipul

“…Heterogeneity of treatment effects in inflammatory bowel disease (IBD) means that many individuals or patient subgroups depart from the average for whom the…”
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Review article: Externally derived control arms—An opportunity for clinical trials in inflammatory bowel disease? by Honap, Sailish, Peyrin‐Biroulet, Laurent

“…Summary Background One of the greatest challenges in the current IBD clinical trial landscape is, perhaps, the recruitment and retention of eligible…”
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Drug-Induced Acne in Inflammatory Bowel Disease: A Practical Guide for the Gastroenterologist by Temido, Maria José, Honap, Sailish, Bursztejn, Anne Claire, Portela, Francisco, Jairath, Vipul, Danese, Silvio, Spencer, Ashley, Peyrin-Biroulet, Laurent

“…Drug-induced acne is a common side effect to a wide array of pharmacological therapies and is characterized by a monomorphic, papulopustular eruption typically…”
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Basket, Umbrella, and Platform Trials: The Potential for Master Protocol–Based Trials in Inflammatory Bowel Disease by Honap, Sailish, Sands, Bruce E., Jairath, Vipul, Danese, Silvio, Vicaut, Eric, Peyrin-Biroulet, Laurent

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