Search Results - "Homan, P"
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Endothelial insulin receptors differentially control insulin signaling kinetics in peripheral tissues and brain of mice
Published in Proceedings of the National Academy of Sciences - PNAS (03-10-2017)“…Insulin receptors (IRs) on endothelial cells may have a role in the regulation of transport of circulating insulin to its target tissues; however, how this…”
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FoxK1 and FoxK2 in insulin regulation of cellular and mitochondrial metabolism
Published in Nature communications (05-04-2019)“…A major target of insulin signaling is the FoxO family of Forkhead transcription factors, which translocate from the nucleus to the cytoplasm following…”
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Lipodystrophy Due to Adipose Tissue-Specific Insulin Receptor Knockout Results in Progressive NAFLD
Published in Diabetes (New York, N.Y.) (01-08-2016)“…Ectopic lipid accumulation in the liver is an almost universal feature of human and rodent models of generalized lipodystrophy and is also a common feature of…”
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Mutations in SERPINF1 cause osteogenesis imperfecta type VI
Published in Journal of bone and mineral research (01-12-2011)“…Osteogenesis imperfecta (OI) is a spectrum of genetic disorders characterized by bone fragility. It is caused by dominant mutations affecting the synthesis…”
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Clozapine as an early‐stage treatment
Published in Acta psychiatrica Scandinavica (01-10-2018)Get full text
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Sclerostin Antibody Treatment Improves the Bone Phenotype of Crtap–/– Mice, a Model of Recessive Osteogenesis Imperfecta
Published in Journal of bone and mineral research (01-05-2016)“…ABSTRACT Osteogenesis imperfecta (OI) is characterized by low bone mass, poor bone quality, and fractures. Standard treatment for OI patients is limited to…”
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P321 Neuronal activity correlates with treatment response to transcranial magnetic stimulation (TMS) in auditory verbal hallucinations (AVH)
Published in Clinical neurophysiology (01-03-2017)“…Introduction About 40–80% of patients with schizophrenia suffer from auditory verbal hallucinations (AVH). In about a third of these AVH patients,…”
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Connective tissue alterations in Fkbp10-/- mice
Published in Human molecular genetics (15-09-2014)“…Osteogenesis imperfecta (OI) is an inherited brittle bone disorder characterized by bone fragility and low bone mass. Loss of function mutations in…”
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Cerebral blood flow identifies responders to transcranial magnetic stimulation in auditory verbal hallucinations
Published in Translational psychiatry (20-11-2012)“…Auditory hallucinations comprise a critical domain of psychopathology in schizophrenia. Repetitive transcranial magnetic stimulation (TMS) has shown promise as…”
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Trends in Heart Failure Incidence and Survival in a Community-Based Population
Published in JAMA : the journal of the American Medical Association (21-07-2004)“…CONTEXT The epidemic of heart failure has yet to be fully investigated, and data on incidence, survival, and sex-specific temporal trends in community-based…”
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11
Understanding Competition in Social Space: Religious Congregations in Manhattan, 1949 to 1999
Published in American sociological review (01-02-2024)“…Competition between social units has long been central to sociological theories of change. Understanding it has become particularly important in the sociology…”
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Differential effects of collagen prolyl 3-hydroxylation on skeletal tissues
Published in PLoS genetics (01-01-2014)“…Mutations in the genes encoding cartilage associated protein (CRTAP) and prolyl 3-hydroxylase 1 (P3H1 encoded by LEPRE1) were the first identified causes of…”
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Serotonin versus catecholamine deficiency: behavioral and neural effects of experimental depletion in remitted depression
Published in Translational psychiatry (17-03-2015)“…Despite immense efforts into development of new antidepressant drugs, the increases of serotoninergic and catecholaminergic neurotransmission have remained the…”
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Customized Virtual Simulations Provide an Interactive Lab Experience
Published in Journal of microbiology & biology education (01-04-2022)“…Although various resources exist for facilitating online laboratory courses, stitching together disparate elements from multiple sources may not be sufficient…”
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Generalized connective tissue disease in Crtap-/- mouse
Published in PloS one (11-05-2010)“…Mutations in CRTAP (coding for cartilage-associated protein), LEPRE1 (coding for prolyl 3-hydroxylase 1 [P3H1]) or PPIB (coding for Cyclophilin B [CYPB]) cause…”
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Differenital Behavioral and Neural Consequences of Serotonin and Catecholamine Deficiency in Depression: an Experimental Study
Published in European psychiatry (28-03-2015)“…Introduction Psychopathological and biological markers that predict response to antidepressant drugs that selectively increase serotonin and/or…”
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S.26.03 Dopaminergic dysfunction and reward learning in bulimia nervosa
Published in European neuropsychopharmacology (01-10-2013)Get full text
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Excessive transforming growth factor-β signaling is a common mechanism in osteogenesis imperfecta
Published in Nature medicine (01-06-2014)“…Osteogenesis imperfecta (OI) is a debilitating illness marked by brittle bones and fractures, as well as extraskeletal abnormalities. Now, Ingo Grafe and…”
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Differential roles of FOXO transcription factors on insulin action in brown and white adipose tissue
Published in The Journal of clinical investigation (01-10-2021)“…Insulin and IGF-1 are essential for adipocyte differentiation and function. Mice lacking insulin and IGF-1 receptors in fat (FIGIR-KO, fat-specific IGF-1…”
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Attachment to parents and to God: a panel-data approach
Published in Journal of contemporary religion (02-09-2019)“…Research at the nexus of attachment theory and religion has generally been constrained both by data limitations and by a view of attachment style as fixed…”
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