Search Results - "Hom, Marisa E"

Targeting colorectal cancer with small-molecule inhibitors of ALDH1B1 by Feng, Zhiping, Hom, Marisa E., Bearrood, Thomas E., Rosenthal, Zachary C., Fernández, Daniel, Ondrus, Alison E., Gu, Yuchao, McCormick, Aaron K., Tomaske, Madeline G., Marshall, Cody R., Kline, Toni, Chen, Che-Hong, Mochly-Rosen, Daria, Kuo, Calvin J., Chen, James K.

“…Aldehyde dehydrogenases (ALDHs) are promising cancer drug targets, as certain isoforms are required for the survival of stem-like tumor cells. We have…”
Get full text

First Clinical Results of Fluorescence Lifetime-enhanced Tumor Imaging Using Receptor-targeted Fluorescent Probes by Pal, Rahul, Hom, Marisa E, van den Berg, Nynke S, Lwin, Thinzar M, Lee, Yu-Jin, Prilutskiy, Andrey, Faquin, William, Yang, Eric, Saladi, Srinivas V, Varvares, Mark A, Rosenthal, Eben L, Kumar, Anand T N

“…Fluorescence molecular imaging, using cancer-targeted near infrared (NIR) fluorescent probes, offers the promise of accurate tumor delineation during surgeries…”
Get full text

Identification of Optimal Tissue-Marking Dye Color for Pathological Evaluation in Fluorescence Imaging Using IRDye800CW by Kondo, Takahito, Nishio, Naoki, Park, Jason S., Mani, Lucas D., Naveed, Abdullah, Tanaka, Hidenori, Lewis, James S., Rosenthal, Eben L., Hom, Marisa E.

“…Purpose Fluorescence-guided surgery using a tumor-specific antibody-dye conjugate is useful in various cancer types. Fluorescence imaging is a valuable tool…”
Get full text

Bicyclic Imidazolium Inhibitors of Gli Transcription Factor Activity by Hom, Marisa E., Ondrus, Alison E., Sakata‐Kato, Tomoyo, Rack, Paul G., Chen, James K.

“…Gli transcription factors within the Hedgehog (Hh) signaling pathway direct key events in mammalian development and promote a number of human cancers. Current…”
Get full text

Infrared Fluorescence-guided Surgery for Tumor and Metastatic Lymph Node Detection in Head and Neck Cancer by White, Haley W, Naveed, Abdullah Bin, Campbell, Benjamin R, Lee, Yu-Jin, Baik, Fred M, Topf, Michael, Rosenthal, Eben L, Hom, Marisa E

“…In patients with head and neck cancer (HNC), surgical removal of cancerous tissue presents the best overall survival rate. However, failure to obtain negative…”
Get full text

The Use of Panitumumab-IRDye800CW in a Novel Murine Model for Conjunctival Squamous Cell Carcinoma by Youn, Gun Min, Case, Ayden G., Jarin, Trent, Li, BaoXiang, Swarup, Aditi, Naranjo, Andrea, Bou-Khalil, Charbel, Yao, Jacqueline, Zhou, Quan, Hom, Marisa E., Rosenthal, Eben L., Wu, Albert Y.

“…PurposeConjunctival squamous cell carcinoma (SCC) is a sight-threatening ocular surface malignancy with the primary treatment modality being surgical…”
Get full text

Synthesis and Chemical Reactivity of a 6-Me-3,2-Hydroxypyridinone Dithiazolide with Primary Amines: A route to New Hexadentate Chelators for Hard Metal(III) Ions by Pailloux, Sylvie L., Nguyen, Sean, Zhou, Stephanie, Hom, Marisa E., Keyser, Michelle N., Smiles, Danil, Raymond, Kenneth N.

“…A hydroxypyridinone building block, bifunctionalized with thiazoline, has been prepared from orthogonally protected…”
Get full text

Two Sides of the Same Coin: Separable Inhibitory Action Against Gli and ALDH1B1 Activity by Hom, Marisa E

“…Small molecules are powerful tools that enable the interrogation of complex biological questions and provide insights into routes for modulating these…”
Get full text