Search Results - "Holzman, Tom"

Preparation and characterization of nitrilotriacetic-acid-terminated self-assembled monolayers on gold surfaces for matrix-assisted laser desorption ionization-time of flight-mass spectrometry analysis of proteins and peptides by Shen, Jianwei, Ahmed, Tanveer, Vogt, Andrew, Wang, Jieyi, Severin, Jean, Smith, Richard, Dorwin, Sally, Johnson, Robert, Harlan, John, Holzman, Tom

“…On-target affinity capture, enrichment and purification of biomolecules improve detection of specific analytes from complex biological samples in…”
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Pseudosubstrate Peptides Inhibit Akt and Induce Cell Growth Inhibition by Luo, Yan, Smith, Richard A, Guan, Ran, Liu, Xuesong, Klinghofer, Vered, Shen, Jianwei, Hutchins, Charles, Richardson, Paul, Holzman, Tom, Rosenberg, Saul H, Giranda, Vincent L

“…We have designed peptide inhibitors that potently inhibit Akt both in vitro and inside cells. These peptide inhibitors are selective for Akt versus other…”
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Protein fragmentation via liquid chromatography–quadrupole time-of-flight mass spectrometry: The use of limited sequence information in structural characterization by Johnson, Robert W., Ahmed, Tanveer F., Miesbauer, Laura J., Edalji, Rohinton, Smith, Richard, Harlan, John, Dorwin, Sarah, Walter, Karl, Holzman, Tom

“…Fragmentation and “top–down” sequencing of intact proteins by mass spectrometry (MS) is most commonly performed by infusion of protein solutions into Fourier…”
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Chkl binds and phosphorylates BAD protein by Han, Edward Kyu-ho, Butler, Chris, Zhang, Haichao, Severin, Jean M, Qin, Wenying, Holzman, Tom F, Gubbins, Earl J, Simmer, Robert L, Rosenberg, Saul, Giranda, Vincent L, Ng, Shi-Chung, Luo, Y

“…Chk1 (checkpoint kinase 1) is a serine-threonine kinase that is critical for G2/M arrest in response to DNA damage. Chk1 phosphorylates Cdc25C at serine-216, a…”
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A highly potent and selective farnesyltransferase inhibitor ABT-100 in preclinical studies by Gu, Wen-Zhen, Joseph, Ingrid, Wang, Yi-Chun, Frost, David, Sullivan, Gerard M, Wang, Le, Lin, Nan-Horng, Cohen, Jerry, Stoll, Vincent S, Jakob, Clarissa G, Muchmore, Steven W, Harlan, John E, Holzman, Tom, Walten, Karl A, Ladror, Uri S, Anderson, Mark G, Kroeger, Paul, Rodriguez, Luis E, Jarvis, Kenneth P, Ferguson, Debra, Marsh, Kennan, Ng, Shichung, Rosenberg, Saul H, Sham, Hing L, Zhang, Haiying

“…Ras mutation has been detected in approximately 20–30% of all human carcinomas, primarily in pancreatic, colorectal, lung and bladder carcinomas. The indirect…”
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Abrogation of G2 checkpoint specifically sensitize p53 defective cells to cancer chemotherapeutic agents by Luo, Y, Rockow-Magnone, S K, Joseph, M K, Bradner, J, Butler, C C, Tahir, S K, Han, E K, Ng, S C, Severin, J M, Gubbins, E J, Reilly, R M, Rueter, A, Simmer, R L, Holzman, T F, Giranda, V L

“…Chkl is a checkpoint gene that is activated after DNA damage. It phosphorylates and inactivates Cdc25C at the late G2 phase. The inactivation of Cdc25C and…”
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Chk1 Binds and Phosphorylates BAD Protein by HAN, Edward Kyu-Ho, BUTLER, Chris, HAICHAO ZHANG, ROSENBERG, Saul, GIRANDA, Vincent L, NG, Shi-Chung, LUO, Y

“…Chk1 (checkpoint kinase 1) is a serine-threonine kinase that is critical for G2/M arrest in response to DNA damage. Chk1 phosphorylates Cdc25C at serine-216, a…”
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The Activity of Trypsin by Russo, Salvatore F, Holzman, Tom

“…Describes an experiment that illustrates the following points concerning the experimental determination of trypsin activity: (1) there is a difference in…”
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The activity of trypsin by Russo, Salvatore F, Holzman, Tom

“…Adaptation of an experiment entitled "The Turnover Number of Trypsin and Chymotrypsin" to illustrate the difference in basing enzyme concentration on weight,…”
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