Search Results - "Holzerová, Milena"

Deep Molecular Response Achieved with Chemotherapy, Dasatinib and Interferon α in Patients with Lymphoid Blast Crisis of Chronic Myeloid Leukaemia by Vráblová, Lucia, Divoký, Vladimír, Kořalková, Pavla, Poláková, Kateřina Machová, Kriegová, Eva, Janská, Romana, Grohmann, Jan, Holzerová, Milena, Papajík, Tomáš, Faber, Edgar

“…The treatment outcome in patients with chronic myeloid leukaemia (CML) in blast crisis (BC) is unsatisfactory despite the use of allogeneic stem cell…”
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Pathogenetic role of ETV6 fusion gene in leukemic transformation of myelodysplastic syndrome refractory anemia with excess blasts-1 with a new, rare translocation t(11;19)(q24.3;q13.12) and insertion ins(6;12)(p22.3p13) by Jarošová, Marie, Roho, Petr, ivná, Jarmila, Peková, So a, Nedomová, Radka, Holzerová, Milena, Mi ková, Pavla, Reptová, Silvie, Papajík, Tomáš, Indrák, Karel

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Operational cures after interferon-alpha in patients with chronic myeloid leukemia in Central and Northern Moravia by Faber, Edgar, Kuba, Adam, Zapletalová, Jana, Divoká, Martina, Rožmanová, Šárka, Rohoň, Peter, Holzerová, Milena, Jarošová, Marie, Indrák, Karel

“…We assessed long-term outcome of 118 consecutive patients in chronic phase of chronic myeloid leukemia (CML) treated with interferon-alpha (IFN-α) in the…”
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Intermittent dosage of imatinib mesylate in CML patients with a history of significant hematologic toxicity after standard dosing by Faber, Edgar, Naušová, Jitka, Jarošová, Marie, Egorin, Merrill J., Holzerová, Milena, Ro manová, Šárka, Marešová, Ivana, Divoký, Vladimír, Indrák, Karel

“…Hematologic toxicity is reported as one of the most important problems connected with imatinib mesylate (IM) treatment in patients with chronic myelogenous…”
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Treatment with low-dose tyrosine kinase inhibitors due to significant haematologic toxicity in patients with CML with prolonged treatment failure prevents haematologic progression by Vráblová, Lucia, Klamová, Hana, Skoumalová, Ivana, Navrátilová, Jana, Janská, Romana, Grohmann, Jan, Holzerová, Milena, Faber, Edgar

“…A lower dosage of tyrosine kinase inhibitors (TKIs) in patients with chronic myeloid leukaemia (CML) has shown efficacy in managing short-term toxicity and…”
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Gain of chromosome 2p in chronic lymphocytic leukemia: significant heterogeneity and a new recurrent dicentric rearrangement by Jarosova, Marie, Urbankova, Helena, Plachy, Radek, Papajik, Tomas, Holzerova, Milena, Balcarkova, Jana, Pikalova, Zuzana, Divoky, Vladimir, Indrak, Karel

“…Array-based comparative genomic hybridization (arrayCGH) studies in chronic lymphocytic leukemia (CLL) have revealed novel recurrent chromosomal imbalances,…”
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Spontaneous splenic rupture in a patient with acute promyelocytic leukaemia during induction chemotherapy by Kuba, Adam, Szotkowski, Tomas, Rohon, Peter, Faber, Edgar, Turcsanyi, Peter, Hubacek, Jaromir, Holzerova, Milena, Prasil, Vojtech, Jarosova, Marie, Indrak, Karel

“…Acute promyelocytic leukaemia (APL) is a subtype of acute myeloid leukaemia with high curability rates. However, it is often accompanied by severe coagulopathy…”
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Gain of chromosome arm 1q in patieznts in relapse and progression of multiple myeloma by Balcarkova, Jana, Urbankova, Helena, Scudla, Vlastimil, Holzerova, Milena, Bacovsky, Jaroslav, Indrak, Karel, Jarosova, Marie

“…Abstract Abnormalities of chromosome 1 are among the most frequent chromosomal aberrations in patients with multiple myeloma (MM) and are considered a…”
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Gain of chromosome arm 1q in patients in relapse and progression of multiple myeloma by Balcárková, Jana, Urbánková, Helena, Scudla, Vlastimil, Holzerová, Milena, Bacovský, Jaroslav, Indrák, Karel, Jarosová, Marie

“…Abnormalities of chromosome 1 are among the most frequent chromosomal aberrations in patients with multiple myeloma (MM) and are considered a poor-risk genetic…”
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Treatment of Chronic Myelomonocytic Leukemia with 5-Azacytidine : Case Reports by Rohon, Peter, Vondrakova, Jana, Jonasova, Anna, Holzerova, Milena, Jarosova, Marie, Indrak, Karel

“…Epigenetic therapy with hypomethylating agent (5-azacytidine; AZA) is common in the management of specific subtypes of myelodysplastic syndrome (MDS), but…”
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Array comparative genomic hybridization in the detection of chromosomal abnormalities in T-cell prolymphocytic leukemia by Urbánková, Helena, Holzerová, Milena, Balcárková, Jana, Raida, Ludĕk, Procházka, Vít, Pikalová, Zuzana, Papajík, Tomáš, Indrák, Karel, Jarošová, Marie

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Imatinib mesylate efficacy in 72 previously treated Philadelphia-positive chronic myeloid leukemia patients with and without additional chromosomal changes: single-center results by Holzerová, Milena, Faber, Edgar, Veselovská, Jitka, Urbánková, Helena, Balcárková, Jana, Rožmanová, Šárka, Voglová, Jaroslava, Mužík, Jan, Chroust, Karel, Indrák, Karel, Jarošová, Marie

“…Abstract Reported here are 72 previously treated Philadelphia chromosome–positive (Ph+) CML patients on imatinib (IM) therapy, with a focus on patients with…”
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Clinical Impact of Basophilia during Cytoreduction in Patients with Chronic Myeloid Leukaemia by Vrablova, Lucia, Hrbcekova, Lucia, Kriegova, Eva, Radvansky, Martin, Papajik, Tomas, Minarik, Jiri, Divoka, Martina, Holzerova, Milena, Janska, Romana, Cernan, Martin, Faber, Edgar

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Complex karyotype as a predictor of high-risk chronic lymphocytic leukemia: A single center experience over 12 years by Kruzova, Lenka, Schneiderova, Petra, Holzerova, Milena, Vatolikova, Michaela, Divoka, Martina, Turcsanyi, Peter, Urbanova, Renata, Kudelka, Milos, Radvansky, Martin, Kriegova, Eva, Papajik, Tomas, Urbankova, Helena

“…•Complex karyotype affects clinical and treatment decision-making in the diagnosis of chronic lymphocytic leukemia.•Complex karyotype is a marker of poor…”
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Gender, Age and TP53 Aberrations in Context of Complex Karyotypes in Chronic Lymphocytic Leukemia Patients in the Era of Chemo +/- Immunotherapy by Kruzova, Lenka, Schneiderova, Petra, Holzerova, Milena, Vatolikova, Michaela, Divoka, Martina, Turcsanyi, Peter, Urbanova, Renata, Kudelka, Milos, Radvansky, Martin, Kriegova, Eva, Papajik, Tomas, Urbankova, Helena

“…Chronic lymphocytic leukemia (CLL) is the most common adult leukemia characterized by a heterogeneous course of the disease. Determination of prognosis of…”
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Chromosomal aberrations in childhood acute lymphoblastic leukemia: 15-year single center experience by Jarosova, Marie, Volejnikova, Jana, Porizkova, Ilona, Holzerova, Milena, Pospisilova, Dagmar, Novak, Zbynek, Vrbkova, Jana, Mihal, Vladimir

“…Abstract Genetic analysis of leukemic cells significantly impacts prognosis and treatment stratification in childhood acute lymphoblastic leukemia (ALL). Our…”
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Complex karyotype and translocation t(4;14) define patients with high-risk newly diagnosed multiple myeloma: results of CMG2002 trial by Nemec, Pavel, Zemanova, Zuzana, Kuglik, Petr, Michalova, Kyra, Tajtlova, Jana, Kaisarova, Petra, Oltova, Alexandra, Filkova, Hana, Holzerova, Milena, Balcarkova, Jana, Jarosova, Marie, Rabasova, Jana, Hruba, Martina, Spicka, Ivan, Gregora, Evzen, Adam, Zdenek, Scudla, Vlastimil, Maisnar, Vladimir, Schutzova, Miroslava, Hajek, Roman

“…Abstract The prognostic impact of chromosomal abnormalities was evaluated by fluorescence in situ hybridization with cytoplasmic immunoglobulin light chain…”
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Deep Molecular Response Achieved with Chemotherapy, Dasatinib and Interferon α in Patients with Lymphoid Blast Crisis of Chronic Myeloid Leukaemia by Vráblová, Lucia, Divoký, Vladimír, Kořalková, Pavla, Poláková, Kateřina Machová, Kriegová, Eva, Janská, Romana, Grohmann, Jan, Holzerová, Milena, Papajík, Tomáš, Faber, Edgar

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Expression of miR-15a and miR-16-1 in patients with chronic lymphocytic leukemia by Humplikova, Lenka, Kollinerova, Sona, Papajik, Tomas, Pikalova, Zuzana, Holzerova, Milena, Prochazka, Vit, Divoka, Martina, Modriansky, Martin, Indrak, Karel, Jarosova, Marie

“…MicroRNAs (miRNAs) are small non-coding single-stranded RNA molecules that regulate gene expression at the post-transcriptional level. In the pathogenesis of…”
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An adult multifocal medulloblastoma with diffuse acute postoperative cerebellar swelling: immunohistochemical and molecular genetics analysis by Balik, Vladimir, Trojanec, Radek, Holzerova, Milena, Tuckova, Lucie, Sulla, Igor, Megova, Magdalena, Vaverka, Miroslav, Hrabalek, Lumir, Ehrmann, Jiri

“…Medulloblastoma (MB), the most common malignant tumor typically affecting children, occurs only exceptionally in adults. Multifocal presentation of this…”
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