Search Results - "Holzer, Tatjana"
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miR-322 stabilizes MEK1 expression to inhibit RAF/MEK/ERK pathway activation in cartilage
Published in Development (Cambridge) (01-10-2017)“…Cartilage originates from mesenchymal cell condensations that differentiate into chondrocytes of transient growth plate cartilage or permanent cartilage of the…”
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Mitochondrial respiratory chain function promotes extracellular matrix integrity in cartilage
Published in The Journal of biological chemistry (01-10-2021)“…Energy metabolism and extracellular matrix (ECM) function together orchestrate and maintain tissue organization, but crosstalk between these processes is…”
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miR‐126‐3p Promotes Matrix‐Dependent Perivascular Cell Attachment, Migration and Intercellular Interaction
Published in Stem cells (Dayton, Ohio) (01-05-2016)“…microRNAs (miRNAs) can regulate the interplay between perivascular cells (PVC) and endothelial cells (EC) during angiogenesis, but the relevant PVC‐specific…”
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8 Multiparameter characterization of CAR T cells
Published in Journal for immunotherapy of cancer (01-11-2021)“…BackgroundAdoptive cell transfer of chimeric antigen receptor (CAR) modified T cells has demonstrated great therapeutic success against certain hematological…”
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Anti-CD19 CARs displayed at the surface of lentiviral vector particles promote transduction of target-expressing cells
Published in Molecular therapy. Methods & clinical development (11-06-2021)“…Recently, a rare type of relapse was reported upon treating a B cell acute lymphoblastic leukemia (B-ALL) patient with anti-CD19 chimeric antigen receptor…”
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036 - Heparan sulfate-deficiency results in altered matrix properties and impaired cell matrix interactions
Published in Osteoarthritis and cartilage (01-04-2024)Get full text
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Heparan sulfate-deficiency results in altered matrix properties and impaired cell matrix interactions
Published in Osteoarthritis and cartilage (01-04-2024)Get full text
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Culture expansion of CAR T cells results in aberrant DNA methylation that is associated with adverse clinical outcome
Published in Leukemia (01-09-2023)“…Chimeric antigen receptor (CAR) T cells provide new perspectives for treatment of hematological malignancies. Manufacturing of these cellular products includes…”
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MiR-26a modulates extracellular matrix homeostasis in cartilage
Published in Matrix biology (01-04-2015)“…MicroRNAs (miRNAs) may represent new therapeutic targets for bone and joint diseases. We hypothesized that several cartilage-specific proteins are targeted by…”
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Live imaging of active fluorophore labelled Wnt proteins
Published in FEBS letters (04-06-2012)“…► Fluorophore tagged Wnts are active in bona fide Wnt signalling assays. ► A subpopulation of Wnt proteins localizes at the tips of long filopodia. ► Wnt…”
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Respiratory chain inactivation links cartilage-mediated growth retardation to mitochondrial diseases
Published in The Journal of cell biology (03-06-2019)“…In childhood, skeletal growth is driven by transient expansion of cartilage in the growth plate. The common belief is that energy production in this hypoxic…”
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Imbalance of Mitochondrial Respiratory Chain Complexes in the Epidermis Induces Severe Skin Inflammation
Published in Journal of investigative dermatology (01-01-2018)“…Accumulation of large-scale mitochondrial DNA (mtDNA) deletions and chronic, subclinical inflammation are concomitant during skin aging, thus raising the…”
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