Search Results - "Holtzman, Julia"

Long-term potentiation is independent of the C-tail of the GluA1 AMPA receptor subunit by Díaz-Alonso, Javier, Morishita, Wade, Incontro, Salvatore, Simms, Jeffrey, Holtzman, Julia, Gill, Michael, Mucke, Lennart, Malenka, Robert C, Nicoll, Roger A

“…We tested the proposal that the C-terminal domain (CTD) of the AMPAR subunit GluA1 is required for LTP. We found that a knock-in mouse lacking the CTD of GluA1…”
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Iduronate-2-sulfatase transport vehicle rescues behavioral and skeletal phenotypes in a mouse model of Hunter syndrome by Arguello, Annie, Meisner, René, Thomsen, Elliot R, Nguyen, Hoang N, Ravi, Ritesh, Simms, Jeffrey, Lo, Iris, Speckart, Jessica, Holtzman, Julia, Gill, Thomas M, Chan, Darren, Cheng, Yuhsiang, Chiu, Chi-Lu, Dugas, Jason C, Fang, Meng, Lopez, Isabel A, Solanoy, Hilda, Tsogtbaatar, Buyankhishig, Zhu, Yuda, Bhalla, Akhil, Henne, Kirk R, Henry, Anastasia G, Delucchi, Anthony, Costanzo, Simona, Harris, Jeffrey M, Diaz, Dolores, Scearce-Levie, Kimberly, Sanchez, Pascal E

“…Mucopolysaccharidosis type II (MPS II) is a lysosomal storage disorder caused by deficiency of the iduronate-2-sulfatase (IDS) enzyme, resulting in cellular…”
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Tau activation of microglial cGAS–IFN reduces MEF2C-mediated cognitive resilience by Udeochu, Joe C., Amin, Sadaf, Huang, Yige, Fan, Li, Torres, Eileen Ruth S., Carling, Gillian K., Liu, Bangyan, McGurran, Hugo, Coronas-Samano, Guillermo, Kauwe, Grant, Mousa, Gergey Alzaem, Wong, Man Ying, Ye, Pearly, Nagiri, Ravi Kumar, Lo, Iris, Holtzman, Julia, Corona, Carlo, Yarahmady, Allan, Gill, Michael T., Raju, Ravikiran M., Mok, Sue-Ann, Gong, Shiaoching, Luo, Wenjie, Zhao, Mingrui, Tracy, Tara E., Ratan, Rajiv R., Tsai, Li-Huei, Sinha, Subhash C., Gan, Li

“…Pathological hallmarks of Alzheimer’s disease (AD) precede clinical symptoms by years, indicating a period of cognitive resilience before the onset of…”
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TAU ablation in excitatory neurons and postnatal TAU knockdown reduce epilepsy, SUDEP, and autism behaviors in a Dravet syndrome model by Shao, Eric, Chang, Che-Wei, Li, Zhiyong, Yu, Xinxing, Ho, Kaitlyn, Zhang, Michelle, Wang, Xin, Simms, Jeffrey, Lo, Iris, Speckart, Jessica, Holtzman, Julia, Yu, Gui-Qiu, Roberson, Erik D, Mucke, Lennart

“…Intracellular accumulation of TAU aggregates is a hallmark of several neurodegenerative diseases. However, global genetic reduction of TAU is beneficial also…”
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ETV:SGSH, a brain-penetrant enzyme transport vehicle for SGSH, improves lysosomal and microglial morphology, degeneration and cognitive behavior in MPS IIIA mice by Masoud, Shababa T., Nguyen, Hoang, Discenza, Claire, Joy, David, Simms, Jeffrey, Lo, Iris, Chun, You Young, Holtzman, Julia, Tsogtbaatar, Khishig, Leung, Amy Wing-Sze, Becerra, Isabel, Thomsen, Elliot, Gill, Audrey, Rajendra, Yashas, Seay, Alexander, Jafarnejad, Mohammad, Bakardjiev, Anna, Calvert, Meredith E.K., Mahon, Cathal S., Thorne, Robert, Chessler, Steven, Henne, Kirk, Sanchez, Pascal, Arguello, Annie

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Iduronate-2-sulfatase transport vehicle rescues neurobehavioral and skeletal phenotypes in a mouse model of mucopolysaccharidosis type II by Arguello, Annie, Meisner, René, Thomsen, Elliot R., Ravi, Ritesh, Simms, Jeffrey, Speckart, Jessica, Holtzman, Julia, Gill, Michael, Cheng, Yuhsiang, Chiu, Chi-Lu, Fang, Meng, Nguyen, Hoang N., Solanoy, Hilda, Tsogtbaatar, Buyankhishig, Zhu, Yuda, Bhalla, Akhil, Henry, Anastasia G., Delucchi, Anthony, Costanzo, Simona, Harris, Jeffrey M., Diaz, Dolores, Troyer, Matthew D., Scearce-Levie, Kimberly, Sanchez, Pascal E.

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Iduronate-2-sulfatase transport vehicle rescues behavioral and skeletal phenotypes in a mouse model of Hunter syndrome by Arguello, Annie, Meisner, René, Thomsen, Elliot R., Nguyen, Hoang N., Ravi, Ritesh, Simms, Jeffrey, Lo, Iris, Speckart, Jessica, Holtzman, Julia, Gill, Thomas M., Chan, Darren, Cheng, Yuhsiang, Chiu, Chi-Lu, Dugas, Jason C., Fang, Meng, Lopez, Isabel A., Solanoy, Hilda, Tsogtbaatar, Buyankhishig, Zhu, Yuda, Bhalla, Akhil, Henne, Kirk R., Henry, Anastasia G., Delucchi, Anthony, Costanzo, Simona, Harris, Jeffrey M., Diaz, Dolores, Scearce-Levie, Kimberly, Sanchez, Pascal E.

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